Detailed information NTG0921234

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: AB3454_RS13545
• Genome accession: NZ_CP162418
• Coordinates: 2726631..2727905 (+)
• Length: 424 a.a.
• NCBI ID: WP_001279338.1
• Uniprot ID: A0A0H2XGV4
• Organism: Staphylococcus aureus strain TUM22750
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2721631..2732905

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB3454_RS13525 (AB3454_13525)	-	2722955..2723050 (+)	96	WP_031789489.1	hypothetical protein	-
AB3454_RS13530 (AB3454_13530)	-	2723011..2724141 (-)	1131	WP_000721707.1	HAD family hydrolase	-
AB3454_RS13535 (AB3454_13535)	nagE	2724248..2725714 (-)	1467	WP_000276362.1	N-acetylglucosamine-specific PTS transporter subunit IIBC	-
AB3454_RS13540 (AB3454_13540)	-	2725842..2726459 (-)	618	WP_000287588.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
AB3454_RS13545 (AB3454_13545)	htrA	2726631..2727905 (+)	1275	WP_001279338.1	S1C family serine protease	Regulator
AB3454_RS13550 (AB3454_13550)	tyrS	2727999..2729261 (-)	1263	WP_261921481.1	tyrosine--tRNA ligase	-
AB3454_RS13555 (AB3454_13555)	-	2729643..2730548 (+)	906	WP_000184370.1	transglycosylase domain-containing protein	-
AB3454_RS13560 (AB3454_13560)	-	2730528..2730620 (-)	93	WP_001789987.1	hypothetical protein	-

Sequence

Protein

• Length: 424 a.a.
• Molecular weight: 45802.98 Da
• Isoelectric Point: 9.9696

>NTDB_id=921234 AB3454_RS13545 WP_001279338.1 2726631..2727905(+) (htrA) [Staphylococcus aureus strain TUM22750]
MSDFNHTDHSTTNHSQTPRYRRPKFPWFKTVIVALIAGIIGALLVLGIGKVLNSTILNKDGSTVQTTNNKGGNQLDGQSK
KFGTVHEMIKSVSPTIVGVINMQKASSVDDLLKGKSSKPSEAGVGSGVIYQINNNSAYIVTNNHVIDGANEIRVQLHNKK
QVKAKLVGKDAVTDIAVLKIENTKGIKAIQFANSSKVQTGDSVFAMGNPLGLQFANSVTSGIISASERTIDAETTGGNTK
VSVLQTDAAINPGNSGGALVDINGNLVGINSMKIAATQVEGIGFAIPSNEVKVTIEQLVKHGKIDRPSIGIGLINLKDIP
EEEREQLHTDREDGIYVAKADSDIDLKKGDIITEIDGKKIKDDVDLRSYLYENKKPGESVTVTVIRDGKTKEVKVKLKQQ
KEQPKRQSRSERQSPGQGDRDFFR

Nucleotide

• Length: 1275 bp

>NTDB_id=921234 AB3454_RS13545 WP_001279338.1 2726631..2727905(+) (htrA) [Staphylococcus aureus strain TUM22750]
ATGTCAGATTTTAATCATACAGATCATTCTACAACAAACCATAGCCAAACACCTAGATACAGAAGACCTAAATTTCCATG
GTTTAAAACAGTCATCGTTGCATTGATTGCTGGAATTATTGGTGCACTTCTAGTACTTGGTATAGGCAAAGTATTAAATA
GTACAATTTTAAATAAAGATGGTTCAACTGTTCAGACAACAAATAATAAAGGTGGCAATCAATTAGACGGTCAAAGCAAG
AAATTCGGTACCGTTCATGAAATGATAAAATCTGTCTCCCCTACAATTGTTGGAGTTATTAACATGCAAAAAGCATCAAG
TGTAGACGACTTATTAAAAGGCAAATCATCTAAACCATCTGAAGCTGGAGTAGGTTCAGGTGTTATCTATCAAATAAACA
ACAATTCAGCTTATATCGTTACAAACAATCATGTTATTGATGGCGCAAATGAAATTAGAGTCCAATTACATAATAAAAAA
CAAGTTAAAGCGAAATTAGTTGGTAAAGATGCAGTAACTGATATTGCTGTACTTAAAATTGAAAATACAAAAGGTATTAA
AGCGATTCAATTCGCCAACTCTTCAAAAGTACAAACTGGCGATAGCGTATTCGCAATGGGTAACCCATTAGGATTACAAT
TTGCTAACTCTGTAACATCTGGTATCATTTCAGCAAGCGAACGTACTATTGACGCTGAGACAACTGGTGGCAATACAAAA
GTCAGCGTTCTTCAAACAGATGCTGCTATTAACCCAGGTAACTCAGGTGGCGCATTAGTAGATATTAATGGTAATTTAGT
TGGTATTAACTCAATGAAAATTGCTGCGACACAAGTTGAAGGTATCGGGTTTGCTATTCCAAGTAATGAAGTTAAAGTAA
CAATTGAACAACTTGTAAAACATGGTAAAATTGACCGCCCTTCGATTGGTATTGGTTTAATTAATTTGAAAGATATTCCT
GAAGAAGAGCGCGAGCAACTTCATACTGATAGAGAAGACGGTATTTATGTCGCCAAAGCTGATAGTGATATTGATCTTAA
AAAAGGTGATATTATTACAGAAATTGATGGCAAGAAAATTAAAGATGATGTTGATTTAAGAAGCTATTTATATGAAAATA
AAAAACCTGGTGAATCAGTCACTGTTACCGTTATCCGTGATGGTAAAACAAAAGAAGTTAAAGTGAAATTAAAACAACAA
AAAGAACAACCAAAACGTCAAAGCCGATCAGAACGTCAATCACCTGGCCAAGGCGATAGAGATTTCTTTAGATAA

Domains

Predicted by InterProScan.

• Trypsin-like peptidase domain (Trypsin_2) (125-269)

• PDZ domain (PDZ_2) (307-397)

3D structure

• AlphaFold DB: A0A0H2XGV4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	39.055	94.811	0.37