Detailed information NTG0921040

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: VOI49_RS09900
• Genome accession: NZ_CP142018
• Coordinates: 1966335..1968779 (-)
• Length: 814 a.a.
• NCBI ID: WP_226317243.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae strain lu24
• Function: degradation of ComX (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IScluster/Tn	1969321..1970853	1966335..1968779	flank	542

Gene organization within MGE regions

Location: 1966335..1970853

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VOI49_RS09900	clpC	1966335..1968779 (-)	2445	WP_226317243.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
VOI49_RS09905	-	1968779..1969240 (-)	462	WP_115245552.1	CtsR family transcriptional regulator	-
VOI49_RS09910	-	1969321..1970853 (-)	1533	Protein_1897	IS1182 family transposase	-

Sequence

Protein

• Length: 814 a.a.
• Molecular weight: 90267.94 Da
• Isoelectric Point: 6.7390

>NTDB_id=921040 VOI49_RS09900 WP_226317243.1 1966335..1968779(-) (clpC) [Streptococcus dysgalactiae strain lu24]
MIMYSLKMQEIFRQAQFQAARFDSQYLETWHILLAMARVDHSLAGLVLSEFDAKVAVEEYEAAAILAMGKSPKGQVSHID
FRPQSKTLTNLLQFAQAISQVTKDQEVGSEHVLFAVLLNPDIMATRLLEMAGYAIKDKGNGEPRLADLRKAIEIHAGYSK
EMIKAIHELRKPKKTKNQGSFSDMMKPPSTAGDLADFTRDLTEMASQGLLEPVIGRDAEVSRMIQVLSRKTKNNPVLVGD
AGVGKTALAYGLAQRIANGAIPYELQDMRVLELDMMSVVAGTRFRGDFEERMNQIIDDIESDGKIILFVDELHTIMGSGS
GIDSTLDAANILKPALSRGTLHMVGATTQEEYQKHIEKDAALSRRFAKILIEEPNVEDAYQILIGLKGSYETYHNVTIAD
QAVRTAVKMAHRYLTSKNLPDSAIDLLDEASATVQGMVKKTSPEIITPLDQALIDGDMKKASRLLAKDVKGQHRKPTAVT
EEDILTTLSKLSGIPLEKLSQADSKKYLNLEKELHKRVIGQKDAVSAISRAIRRNQSGIRTGKRPIGSFMFLGPTGVGKT
ELAKALAEVLFDDASALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNILLQ
VLDDGMLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKGISHDHQAMEKRILEELKKTYRPEFINRIDEKVVFH
SLTQDNMREVVKIMVQPLMTTLAEKGITLKFQPMALKYLSEEGYDVEMGARPLRRTLQTQVEDKLSELILAGELASGHTL
KIGLSHGKLSFNIE

Nucleotide

• Length: 2445 bp

>NTDB_id=921040 VOI49_RS09900 WP_226317243.1 1966335..1968779(-) (clpC) [Streptococcus dysgalactiae strain lu24]
ATGATCATGTATTCATTGAAGATGCAAGAAATTTTCAGGCAGGCGCAATTTCAAGCAGCCCGCTTTGATAGCCAATACCT
AGAAACTTGGCATATATTGCTAGCTATGGCGAGGGTTGATCACTCCCTAGCGGGTTTGGTGCTAAGCGAATTTGATGCTA
AGGTTGCAGTGGAAGAATATGAGGCTGCAGCTATTTTAGCTATGGGCAAAAGCCCTAAAGGCCAAGTGTCTCACATTGAC
TTTAGGCCTCAGTCAAAAACCTTAACGAACCTTTTGCAATTTGCCCAAGCTATCAGTCAAGTCACCAAAGACCAAGAGGT
AGGTTCAGAGCATGTTCTCTTTGCCGTTTTGCTTAATCCAGATATTATGGCGACTCGCTTATTAGAGATGGCTGGTTATG
CTATCAAGGATAAAGGAAACGGAGAACCTCGCTTAGCTGATTTACGAAAAGCTATCGAGATTCATGCAGGCTATAGTAAG
GAAATGATTAAGGCTATCCACGAGTTGCGTAAACCAAAGAAAACCAAGAATCAAGGTTCTTTTTCAGACATGATGAAGCC
ACCAAGCACGGCTGGGGATTTGGCAGACTTTACACGTGATTTGACCGAGATGGCAAGCCAAGGTCTCTTAGAGCCAGTTA
TTGGCCGTGATGCTGAAGTATCACGGATGATCCAAGTACTGAGTCGTAAAACCAAGAATAACCCTGTTCTTGTGGGTGAT
GCAGGTGTGGGTAAAACGGCCCTTGCCTATGGTCTTGCCCAACGTATTGCTAATGGTGCTATTCCTTATGAACTGCAAGA
CATGCGTGTTCTAGAATTAGATATGATGAGTGTTGTTGCGGGGACCCGTTTTCGTGGGGATTTTGAAGAGCGCATGAATC
AAATCATTGACGATATTGAGTCAGATGGCAAGATTATTCTCTTCGTAGATGAATTGCACACCATTATGGGATCAGGAAGT
GGTATTGATAGCACACTTGATGCTGCCAATATTTTAAAACCAGCCTTATCTCGCGGAACCCTCCATATGGTGGGTGCAAC
AACGCAGGAAGAATACCAAAAACACATTGAAAAAGATGCCGCTCTTTCGCGTCGCTTTGCTAAGATTTTAATTGAAGAGC
CTAATGTAGAAGATGCTTATCAGATTCTGATCGGGTTAAAAGGCTCTTACGAGACTTACCATAATGTGACCATTGCTGAT
CAGGCTGTTAGAACTGCTGTGAAAATGGCACATCGCTATCTGACCAGCAAAAACCTTCCAGATTCTGCCATTGATTTGCT
AGATGAAGCTAGTGCTACTGTCCAAGGTATGGTTAAAAAAACCAGTCCAGAAATCATCACGCCATTAGATCAAGCTTTGA
TTGATGGCGATATGAAGAAGGCCTCTCGTTTGTTGGCAAAAGACGTTAAAGGACAACATCGTAAGCCAACAGCTGTGACA
GAAGAGGATATCCTGACAACCTTGAGCAAGCTATCAGGTATTCCACTGGAAAAACTCAGCCAAGCTGATAGCAAAAAATA
CCTTAATTTGGAAAAAGAACTGCATAAGCGCGTGATTGGGCAAAAAGATGCTGTCTCAGCTATTTCTCGAGCGATTCGTC
GTAATCAGTCAGGCATCCGTACAGGTAAACGTCCGATTGGTTCCTTCATGTTCCTTGGTCCAACAGGGGTTGGTAAGACT
GAGTTGGCTAAAGCCTTGGCAGAAGTTCTCTTTGACGACGCGTCTGCCCTTATCCGCTTTGATATGTCAGAGTATATGGA
AAAATTTGCGGCTTCTCGTCTTAATGGCGCACCTCCAGGCTATGTCGGTTACGATGAAGGTGGTGAATTAACAGAGAAGG
TCAGAAACAAGCCTTACTCCGTGCTCCTCTTTGACGAGGTGGAAAAAGCTCACCCTGATATTTTCAACATACTCTTACAA
GTGCTTGATGACGGCATGTTGACAGATAGTCGTGGGCGTAAAGTGGACTTCTCAAACACCATTATTATCATGACAAGTAA
TCTAGGGGCAACAGCTCTGCGTGATGATAAAACAGTTGGCTTTGGGGCAAAAGGCATTAGCCATGACCACCAAGCCATGG
AAAAACGGATTTTGGAAGAGTTGAAGAAAACTTACCGACCAGAATTTATCAACCGAATTGATGAAAAGGTTGTCTTCCAC
AGCCTCACTCAGGATAATATGAGAGAAGTGGTCAAGATTATGGTGCAGCCGTTGATGACTACTTTGGCAGAAAAAGGCAT
TACCCTTAAATTCCAGCCAATGGCCCTCAAGTATTTATCAGAAGAAGGGTACGATGTGGAAATGGGTGCTCGTCCATTGC
GCCGTACTTTGCAAACTCAGGTGGAAGATAAATTGTCTGAATTGATTCTTGCTGGTGAATTGGCAAGTGGTCATACCCTG
AAAATTGGTCTTTCTCATGGAAAACTCAGCTTTAACATTGAGTGA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (722-801)

• ATPase family associated with various cellular activities (AAA) (AAA) (236-368)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (15-53)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (95-133)

• AAA lid domain (AAA_lid_9) (376-461)

• AAA domain (Cdc48 subfamily) (AAA_2) (544-715)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus mutans UA159	76.63	99.877	0.765
clpC	Streptococcus thermophilus LMD-9	73.039	100	0.732
clpC	Streptococcus thermophilus LMG 18311	72.794	100	0.73
clpC	Streptococcus pneumoniae TIGR4	66.913	99.877	0.668
clpC	Streptococcus pneumoniae Rx1	66.913	99.877	0.668
clpC	Streptococcus pneumoniae D39	66.913	99.877	0.668
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	48.801	100	0.5
clpC	Bacillus subtilis subsp. subtilis str. 168	43.081	100	0.44