Detailed information NTG0921026

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: VOI49_RS07175
• Genome accession: NZ_CP142018
• Coordinates: 1429057..1431348 (+)
• Length: 763 a.a.
• NCBI ID: WP_226313819.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae strain lu24
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 1424057..1436348

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VOI49_RS07150	feoB	1424147..1426306 (-)	2160	WP_226313815.1	ferrous iron transport protein B	-
VOI49_RS07155	-	1426303..1426782 (-)	480	WP_226313817.1	ferrous iron transport protein A	-
VOI49_RS07160	-	1426980..1427714 (-)	735	WP_115246232.1	amino acid ABC transporter ATP-binding protein	-
VOI49_RS07165	-	1427714..1428400 (-)	687	WP_003051835.1	amino acid ABC transporter permease	-
VOI49_RS07170	-	1428528..1428758 (-)	231	WP_003051836.1	DUF1797 family protein	-
VOI49_RS07175	clpE	1429057..1431348 (+)	2292	WP_226313819.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
VOI49_RS07180	-	1431466..1431921 (+)	456	WP_226313820.1	NUDIX domain-containing protein	-
VOI49_RS07185	-	1431971..1432273 (+)	303	WP_003051842.1	DUF1827 family protein	-
VOI49_RS07190	ileS	1432686..1435487 (-)	2802	WP_003051844.1	isoleucine--tRNA ligase	-

Sequence

Protein

• Length: 763 a.a.
• Molecular weight: 84929.18 Da
• Isoelectric Point: 5.2743

>NTDB_id=921026 VOI49_RS07175 WP_226313819.1 1429057..1431348(+) (clpE) [Streptococcus dysgalactiae strain lu24]
MLCQNCNLNESTIHLYTNVNGKQKQVDLCQNCYQIMKTDPTNPILGGLNGGQRAQERSSTPFFDDFFGDLNNFRAFGNLP
NTPPTQAGQNGNGGGRHGGHFNGQRPTQPQTQNQQVKGLLEEFGINVTDIARHGDIDPVIGRDDEITRVIEILNRRSKNN
PVLIGEPGVGKTAVVEGLAQKIVDGTVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRQRKDVILFIDEIHE
IVGAGSAGDGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVEETITILKGIQPKYEDYHH
VKYSPAAIEAAAHLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKEIDKRLIEAENLKAQATRDEDYERAAYFRDQ
IAKYKEMQAQKVDEQDIPIITEKTIEAIIEQKTNIPVGDLKEKEQSQLVNLANDLKAHVIGQDDAVDKIAKAIRRNRVGL
GTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSADNMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEQVRRNPY
SLILLDEVEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKSEASVGFGAAREGRTSSVLGELSNFFS
PEFMNRFDGIIEFKALSKDNLLHIVDLMLEDVNKRLGYNGIHLDVTQKVKEKLVDLGYDPKMGARPLRRTIQDYIEDAIT
DYYLEHPTEKDLRAIMTSNGNVMIKAAKKDETVTAKQDQTDEN

Nucleotide

• Length: 2292 bp

>NTDB_id=921026 VOI49_RS07175 WP_226313819.1 1429057..1431348(+) (clpE) [Streptococcus dysgalactiae strain lu24]
ATGCTTTGTCAAAATTGTAATTTAAACGAATCAACCATCCACCTCTACACGAATGTTAATGGAAAACAAAAACAAGTTGA
CCTTTGTCAAAACTGTTATCAAATCATGAAGACTGACCCTACTAATCCTATTTTAGGTGGTCTAAATGGAGGTCAAAGAG
CCCAAGAACGCTCATCCACCCCCTTCTTTGATGACTTTTTTGGTGATTTAAATAATTTTAGAGCCTTTGGTAACCTTCCG
AATACCCCGCCTACACAAGCAGGCCAAAATGGCAACGGAGGAGGACGCCATGGTGGTCATTTCAATGGGCAACGTCCCAC
TCAGCCACAAACACAAAATCAGCAAGTAAAGGGCTTGTTAGAAGAATTTGGGATTAATGTTACAGATATTGCAAGACATG
GTGATATTGACCCTGTCATCGGTCGAGATGACGAGATTACACGTGTCATCGAAATCCTTAACCGTCGGTCTAAAAATAAC
CCTGTGCTTATTGGGGAACCAGGAGTTGGTAAAACAGCTGTTGTAGAAGGTCTAGCCCAGAAAATTGTAGATGGCACAGT
ACCTCACAAATTGCAAGGTAAGCAAGTGATTCGTCTAGATGTGGTTAGTCTTGTTCAAGGCACAGGTATCCGTGGTCAAT
TCGAAGAACGCATGCAAAAATTAATGGAAGAAATTCGTCAACGCAAAGATGTGATTCTCTTTATTGATGAAATTCATGAA
ATTGTAGGTGCTGGTTCTGCTGGAGATGGCAATATGGATGCTGGCAATATTTTAAAACCAGCCTTGGCCCGTGGTGAGTT
GCAACTCGTTGGTGCTACTACCTTAAATGAATACCGTATTATTGAAAAAGATGCTGCCTTGGAGCGGCGGATGCAGCCGG
TGAAAGTTGACGAACCTTCTGTAGAAGAAACCATTACCATCTTAAAAGGTATCCAGCCCAAATATGAAGACTATCATCAT
GTCAAATATAGCCCAGCAGCTATCGAGGCTGCTGCACACTTATCCAATCGCTACATTCAAGACCGATTCCTCCCTGATAA
GGCCATTGACCTTCTGGACGAAGCTGGTTCAAAAATGAATTTAACCCTTAATTTTGTTGACCCTAAAGAGATTGACAAAC
GTCTGATTGAAGCAGAAAACCTCAAGGCTCAAGCAACTCGTGACGAAGATTACGAACGAGCAGCCTATTTCCGAGATCAA
ATTGCGAAATACAAGGAAATGCAAGCTCAAAAAGTCGACGAACAGGATATTCCTATCATTACTGAAAAAACCATTGAAGC
CATCATTGAACAAAAAACCAATATTCCAGTTGGCGATTTGAAAGAAAAAGAACAATCTCAACTCGTTAATTTGGCTAATG
ATTTGAAAGCTCACGTGATTGGCCAAGATGATGCCGTTGACAAAATTGCCAAGGCCATTCGCCGGAACCGTGTGGGATTA
GGAACTCCAAATCGTCCTATTGGTTCTTTCCTATTCGTTGGGCCAACAGGTGTTGGTAAAACAGAATTGTCTAAGCAACT
AGCTATTGAACTCTTTGGCTCTGCTGACAATATGATTCGCTTTGACATGTCCGAATACATGGAAAAACATGCCGTTGCTA
AATTAGTCGGGGCTCCTCCTGGTTATGTGGGCTATGAAGAAGCTGGCCAGTTAACGGAACAAGTTCGCCGCAATCCATAT
TCACTTATTCTCTTAGATGAAGTGGAAAAGGCTCATCCTGACGTCATGCACATGTTTTTACAAGTTCTTGATGATGGCCG
TTTAACAGATGGTCAAGGACGAACAGTCAGCTTCAAGGATACTATTATTATCATGACCTCTAATGCCGGAACAGGTAAAA
GTGAAGCTTCTGTTGGATTTGGTGCAGCTAGAGAAGGACGAACAAGTTCTGTCCTTGGTGAATTAAGTAACTTCTTCAGC
CCAGAGTTCATGAACCGTTTCGATGGTATTATTGAATTTAAGGCCTTGAGCAAAGATAACCTCTTGCATATCGTTGATTT
AATGCTGGAAGATGTTAATAAGCGCTTAGGCTATAATGGGATTCACCTTGATGTGACGCAAAAAGTCAAAGAAAAATTAG
TAGATTTAGGCTATGATCCTAAAATGGGTGCTCGACCGCTCCGTCGTACCATCCAAGATTATATCGAAGATGCGATTACG
GACTACTATTTGGAACATCCAACTGAAAAGGACTTGCGTGCCATAATGACAAGTAACGGTAATGTTATGATTAAAGCTGC
CAAAAAAGATGAAACGGTAACAGCTAAACAAGATCAGACCGACGAGAACTAA

Domains

Predicted by InterproScan.

• ATPase family associated with various cellular activities (AAA) (AAA) (162-281)

• AAA domain (Cdc48 subfamily) (AAA_2) (485-648)

• AAA lid domain (AAA_lid_9) (300-397)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (656-730)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	85.317	99.083	0.845
clpE	Streptococcus pneumoniae Rx1	83.663	99.476	0.832
clpE	Streptococcus pneumoniae D39	83.663	99.476	0.832
clpE	Streptococcus pneumoniae R6	83.663	99.476	0.832
clpE	Streptococcus pneumoniae TIGR4	83.531	99.476	0.831
clpC	Lactococcus lactis subsp. cremoris KW2	76.391	96.592	0.738
clpC	Bacillus subtilis subsp. subtilis str. 168	49.635	89.777	0.446
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	46.154	85.19	0.393
clpC	Streptococcus pneumoniae Rx1	47.68	81.913	0.391
clpC	Streptococcus pneumoniae D39	47.68	81.913	0.391
clpC	Streptococcus pneumoniae TIGR4	47.68	81.913	0.391
clpC	Streptococcus mutans UA159	47.419	81.258	0.385
clpC	Streptococcus thermophilus LMD-9	46.057	83.093	0.383
clpC	Streptococcus thermophilus LMG 18311	45.741	83.093	0.38