Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   VO177_RS19435 Genome accession   NZ_CP141828
Coordinates   3882319..3882975 (-) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain TZS01     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 3877319..3887975
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VO177_RS19415 (VO177_19415) spxH 3877556..3878458 (+) 903 WP_003155024.1 protease adaptor protein SpxH -
  VO177_RS19420 (VO177_19420) - 3878745..3878912 (+) 168 WP_003155026.1 hypothetical protein -
  VO177_RS19425 (VO177_19425) pepF 3878950..3880779 (-) 1830 WP_094296111.1 oligoendopeptidase F Regulator
  VO177_RS19430 (VO177_19430) - 3881007..3882167 (-) 1161 WP_100261695.1 competence protein CoiA family protein -
  VO177_RS19435 (VO177_19435) mecA 3882319..3882975 (-) 657 WP_003155032.1 adaptor protein MecA Regulator
  VO177_RS19440 (VO177_19440) - 3883251..3883907 (+) 657 WP_014417421.1 TerC family protein -
  VO177_RS19445 (VO177_19445) spx 3883965..3884360 (-) 396 WP_003155034.1 transcriptional regulator Spx -
  VO177_RS19450 (VO177_19450) - 3884539..3885117 (-) 579 WP_007409110.1 GNAT family N-acetyltransferase -
  VO177_RS19455 (VO177_19455) - 3885235..3886422 (-) 1188 WP_022553557.1 putative glycoside hydrolase -
  VO177_RS19460 (VO177_19460) oppF 3886529..3887446 (-) 918 WP_017417453.1 oligopeptide ABC transporter ATP-binding protein OppF -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=919993 VO177_RS19435 WP_003155032.1 3882319..3882975(-) (mecA) [Bacillus velezensis strain TZS01]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=919993 VO177_RS19435 WP_003155032.1 3882319..3882975(-) (mecA) [Bacillus velezensis strain TZS01]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAAGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895