Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   VO179_RS18925 Genome accession   NZ_CP141827
Coordinates   3912249..3912905 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain XHA14     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 3907249..3917905
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VO179_RS18900 (VO179_18900) oppF 3907779..3908696 (+) 918 WP_012117283.1 oligopeptide ABC transporter ATP-binding protein OppF -
  VO179_RS18905 (VO179_18905) - 3908803..3909990 (+) 1188 WP_076982893.1 putative glycoside hydrolase -
  VO179_RS18910 (VO179_18910) - 3910108..3910686 (+) 579 WP_007409110.1 GNAT family N-acetyltransferase -
  VO179_RS18915 (VO179_18915) spx 3910864..3911259 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  VO179_RS18920 (VO179_18920) - 3911317..3911973 (-) 657 WP_007409109.1 TerC family protein -
  VO179_RS18925 (VO179_18925) mecA 3912249..3912905 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  VO179_RS18930 (VO179_18930) - 3913056..3914216 (+) 1161 WP_040238274.1 competence protein CoiA family protein -
  VO179_RS18935 (VO179_18935) pepF 3914444..3916273 (+) 1830 WP_007409107.1 oligoendopeptidase F Regulator
  VO179_RS18940 (VO179_18940) - 3916311..3916478 (-) 168 WP_003155026.1 hypothetical protein -
  VO179_RS18945 (VO179_18945) spxH 3916765..3917667 (-) 903 WP_039251990.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=919928 VO179_RS18925 WP_003155032.1 3912249..3912905(+) (mecA) [Bacillus velezensis strain XHA14]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=919928 VO179_RS18925 WP_003155032.1 3912249..3912905(+) (mecA) [Bacillus velezensis strain XHA14]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGAAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895