Detailed information NTG0919778

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: VF946_RS10595
• Genome accession: NZ_CP141824
• Coordinates: 2100296..2102746 (-)
• Length: 816 a.a.
• NCBI ID: WP_023371651.1
• Uniprot ID: -
• Organism: Streptococcus suis strain HB18
• Function: degradation of ComW (predicted from homology) Competence regulation

Genomic Context

Location: 2095296..2107746

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VF946_RS10580	hslO	2097747..2098613 (+)	867	WP_024383950.1	Hsp33 family molecular chaperone HslO	-
VF946_RS10585	dusB	2098606..2099610 (+)	1005	WP_023371647.1	tRNA dihydrouridine synthase DusB	-
VF946_RS10590	-	2099711..2100202 (-)	492	WP_023371649.1	adenylyltransferase/cytidyltransferase family protein	-
VF946_RS10595	clpC	2100296..2102746 (-)	2451	WP_023371651.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
VF946_RS10600	-	2102750..2103202 (-)	453	WP_023371653.1	CtsR family transcriptional regulator	-
VF946_RS10605	traF	2103370..2103729 (+)	360	WP_023371655.1	conjugal transfer protein TraF	-
VF946_RS11715	-	2103801..2103914 (-)	114	WP_079278668.1	LPXTG cell wall anchor domain-containing protein	-
VF946_RS10610	-	2104277..2105299 (-)	1023	Protein_2060	Cna B-type domain-containing protein	-
VF946_RS10615	-	2105354..2106493 (-)	1140	WP_024383931.1	Ig-like domain-containing protein	-

Sequence

Protein

• Length: 816 a.a.
• Molecular weight: 90411.91 Da
• Isoelectric Point: 6.2915

>NTDB_id=919778 VF946_RS10595 WP_023371651.1 2100296..2102746(-) (clpC) [Streptococcus suis strain HB18]
MKISTGLQRVFEDAQLVAQRYACDYLETWHVLLSFVINHDTVAGAVLAEYPISISDYEHATFVVTDKVYREELDSFRILP
SSKRLDETASFAKKIAEVVKAKELGTEHLFMAMLLDKRSTASQILDKVGFYFEDSDDKFRFLDLRKNLEARAGFTKEDLK
AIRSVMKGGKAKPTNMGQMMGIPPAPQSGGLEDYTRDLTALAREGKIEPVIGRDAEIARIIQILSRKTKNNPVLVGDAGV
GKTALALGLAQRVAAGDVPVSLAKMRVLELDLMNVIAGTRFRGDFEERMNNIINDIEEDGQVILFIDELHTIMGSGSGID
STLDAANILKPALARGTLRTVGATTQTEYQKHIEKDAALVRRFAKVTIEEPTVEDSIAILTGLKGTFEKYHRVRIGQAAV
ETAVTYAKRYLTSKNLPDSAIDLLDEASATVQNRVKGQAEETGLTSIDKALMDKKYKTVSKLLIKTKEDAEASQNYDLEV
TEEDVLETLSRLSGIPVAKLSQSDTKKYLNLEAELHKRVIGQEEAISAVSRAIRRNQSGIRTGRRPIGSFMFLGPTGVGK
TELAKALAEVLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLL
QVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGALDLSKDHKEVEKRIFEELKKAYRPEFINRIDEKVVF
HSLTETHMQDVVKVMIKPLLAVTAEKGITLKLQPSALKLLAKQGYDPEMGARPLRRLLQTKLEDPLAEMLLRGDLTTGST
LKVGVKGEELKFDVVK

Nucleotide

• Length: 2451 bp

>NTDB_id=919778 VF946_RS10595 WP_023371651.1 2100296..2102746(-) (clpC) [Streptococcus suis strain HB18]
ATGAAAATTTCAACTGGTTTACAGCGGGTTTTTGAAGATGCCCAGTTAGTGGCCCAACGCTATGCCTGTGATTACTTGGA
AACCTGGCATGTTCTCTTGTCTTTCGTTATCAACCATGATACAGTCGCCGGTGCTGTTTTGGCAGAATATCCTATTTCAA
TTTCTGACTATGAACATGCAACTTTTGTTGTGACCGACAAGGTCTATCGTGAAGAGTTGGATAGTTTTCGTATTTTACCA
TCTTCTAAACGTTTGGATGAAACAGCTAGTTTTGCCAAGAAAATTGCAGAAGTCGTCAAGGCTAAGGAGCTGGGAACGGA
ACATTTGTTTATGGCTATGTTGTTGGACAAGCGGTCAACAGCTAGTCAGATTTTGGACAAGGTAGGTTTTTATTTTGAAG
ACTCAGATGATAAGTTTCGTTTCTTGGATTTGCGTAAAAACTTGGAGGCACGTGCGGGATTTACCAAAGAGGACCTTAAA
GCTATCCGCAGTGTGATGAAGGGTGGCAAAGCCAAACCTACCAATATGGGACAGATGATGGGAATACCCCCAGCACCTCA
AAGTGGTGGATTAGAAGACTACACTCGTGATTTGACAGCTTTGGCGCGTGAAGGGAAGATTGAACCTGTCATCGGTCGAG
ACGCTGAGATTGCACGGATAATCCAAATTCTATCACGTAAAACCAAGAATAACCCAGTTCTAGTTGGTGATGCTGGTGTC
GGAAAAACTGCGCTTGCTTTGGGTCTTGCTCAACGTGTTGCTGCAGGTGATGTCCCTGTCAGCTTGGCTAAGATGCGGGT
TTTGGAACTTGACTTGATGAACGTTATCGCTGGAACTCGTTTCCGTGGTGATTTCGAAGAGCGGATGAATAATATCATCA
ACGACATTGAGGAAGATGGTCAAGTCATCCTTTTCATCGATGAGTTGCATACCATTATGGGTTCTGGCTCGGGGATTGAT
TCGACCTTGGATGCAGCCAATATCCTCAAACCAGCTCTTGCTCGTGGCACCCTCCGTACGGTCGGAGCGACGACTCAGAC
AGAGTACCAAAAGCATATTGAGAAAGACGCAGCCCTGGTTCGTCGTTTTGCCAAAGTGACCATTGAAGAGCCGACAGTGG
AAGATAGCATTGCCATTTTGACAGGGCTTAAAGGTACTTTTGAGAAATACCATAGGGTCCGTATTGGACAAGCAGCTGTA
GAGACTGCTGTGACCTACGCTAAGCGGTATTTGACCAGTAAAAACCTGCCAGATTCAGCCATTGATCTGCTGGATGAAGC
CAGTGCAACGGTACAAAATCGAGTGAAAGGGCAGGCTGAGGAAACAGGACTGACGAGTATAGACAAGGCCTTGATGGATA
AAAAATATAAGACTGTCAGCAAGCTTTTGATTAAAACGAAAGAAGATGCCGAGGCTAGTCAAAACTATGACCTTGAAGTA
ACAGAAGAAGATGTTTTAGAAACACTTAGCCGCTTGTCAGGTATCCCAGTAGCCAAGCTTAGCCAATCAGATACTAAGAA
GTATCTGAATCTGGAAGCAGAATTGCACAAGCGTGTGATTGGGCAGGAAGAAGCTATTTCTGCAGTTAGCAGAGCTATTC
GCCGTAATCAGTCAGGGATTCGTACAGGTCGCAGACCGATTGGTTCCTTTATGTTCTTGGGACCAACTGGTGTCGGTAAG
ACAGAGCTTGCTAAAGCCCTGGCAGAGGTTCTCTTTGATGATGAATCTGCTCTTATCCGTTTTGATATGTCCGAGTATAT
GGAGAAATTTGCGGCTAGCCGTCTCAATGGAGCGCCTCCAGGCTACGTGGGCTATGAAGAAGGTGGCGAATTGACAGAAA
AAGTTCGTAATAAACCTTATTCTGTTCTTCTTTTTGATGAGGTTGAAAAGGCTCATCCAGATATTTTCAATGTTCTCTTG
CAGGTCTTGGATGATGGTGTCTTGACGGACAGTAAGGGACGTAAGGTTGATTTCTCAAATACTATTATTATCATGACGTC
AAACCTTGGAGCAACAGCTCTTCGTGATGATAAGACAGTTGGTTTTGGTGCCCTTGATTTATCTAAGGACCACAAGGAAG
TAGAGAAACGCATTTTTGAGGAATTGAAAAAAGCCTATCGTCCAGAATTTATCAACCGTATTGACGAGAAAGTTGTCTTC
CATAGCCTAACGGAAACTCATATGCAGGATGTTGTCAAGGTCATGATTAAACCTTTGTTGGCTGTAACAGCTGAGAAAGG
AATTACCCTTAAACTGCAACCGTCAGCCCTTAAGTTATTGGCTAAACAAGGTTATGACCCAGAAATGGGGGCTCGTCCGC
TACGTAGGCTCTTACAAACCAAATTGGAAGATCCGTTGGCAGAAATGTTACTCCGTGGTGACTTGACTACTGGTTCGACC
TTGAAGGTTGGGGTCAAGGGTGAAGAGCTCAAGTTTGATGTGGTCAAATAG

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (723-803)

• ATPase family associated with various cellular activities (AAA) (AAA) (233-365)

• AAA lid domain (AAA_lid_9) (372-457)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (102-130)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (14-56)

• AAA domain (Cdc48 subfamily) (AAA_2) (545-716)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus pneumoniae Rx1	71.656	99.877	0.716
clpC	Streptococcus pneumoniae D39	71.656	99.877	0.716
clpC	Streptococcus pneumoniae TIGR4	71.656	99.877	0.716
clpC	Streptococcus mutans UA159	66.585	99.755	0.664
clpC	Streptococcus thermophilus LMD-9	63.842	100	0.656
clpC	Streptococcus thermophilus LMG 18311	64.26	100	0.654
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	49.222	100	0.504
clpC	Bacillus subtilis subsp. subtilis str. 168	43.353	100	0.444