Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   VA211_RS04645 Genome accession   NZ_CP141771
Coordinates   965862..967646 (+) Length   594 a.a.
NCBI ID   WP_324684271.1    Uniprot ID   -
Organism   Helicobacter pylori strain P08204     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 960862..972646
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VA211_RS04615 motB 961522..962289 (+) 768 WP_001085316.1 flagellar motor protein MotB -
  VA211_RS04620 - 962293..962730 (+) 438 WP_001031792.1 hypothetical protein -
  VA211_RS04625 - 962911..964572 (+) 1662 WP_324684267.1 ABC transporter permease/substrate-binding protein -
  VA211_RS04630 - 964576..965217 (+) 642 WP_324684268.1 ATP-binding cassette domain-containing protein -
  VA211_RS04635 - 965229..965408 (-) 180 WP_000468796.1 hypothetical protein -
  VA211_RS04640 - 965400..965861 (+) 462 WP_000437188.1 hypothetical protein -
  VA211_RS04645 uvrC 965862..967646 (+) 1785 WP_324684271.1 excinuclease ABC subunit UvrC Machinery gene
  VA211_RS04650 - 967657..968922 (+) 1266 WP_324684273.1 homoserine dehydrogenase -
  VA211_RS04655 - 968923..969267 (+) 345 WP_001211675.1 YraN family protein -
  VA211_RS04660 trxA 969356..969676 (+) 321 WP_000020199.1 thioredoxin -
  VA211_RS04665 trxB 969682..970617 (+) 936 WP_324684282.1 thioredoxin-disulfide reductase -
  VA211_RS04670 - 970783..971604 (+) 822 WP_324684284.1 glycosyltransferase family 25 protein -
  VA211_RS04675 - 971810..972058 (-) 249 WP_000790557.1 RNA-binding protein -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68863.08 Da        Isoelectric Point: 9.6285

>NTDB_id=919367 VA211_RS04645 WP_324684271.1 965862..967646(+) (uvrC) [Helicobacter pylori strain P08204]
MADLLSSLKNLSHSSGVYQYFDKNRQLLYIGKAKNLKKRIRSYFSIHNNEITPNHRASLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCENKITKEEYLKIAKECLEMIENKDKLIKELELKMERLSNNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYSGSHKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLN
ACSNETLKELQDFISHQYSKKIALSIPKKGDKLALIEIAIKNAQEIFSQEKTSSEDLILEEVRSLFQLECMPYRVEIFDT
SHHANSQCVGGMVVYENHEFQKNSYRRYHLKGSNEYTQMSELLTRRALDFNKEPPPNLWVIDGGRVQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTANDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=919367 VA211_RS04645 WP_324684271.1 965862..967646(+) (uvrC) [Helicobacter pylori strain P08204]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTTCTCATAGCAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAGGCGAAAAATTTAAAAAAGCGTATCAGAAGTTATTTTTCTATCCACAATAATGAAATCACGCCCA
ATCATCGTGCAAGCTTACGCATCCAAATGATGGTCAAACAGATCGCTTTTTTAGAAACCATTTTAGTAGAAAACGAGCAA
GACGCTTTGATTTTAGAAAACTCTTTAATCAAGCAGCTCAAACCCAAATACAACATTCTTTTAAGAGATGATAAAACTTA
CCCTTATATTTACATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAAGATATTTTAGACAGCTTGTATGAATTGCTCCCGTTAGTTCAAAAGAAA
AATTGCATCAAAGACAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGAATAAAATCACCAA
AGAAGAGTATTTGAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAAACTCATCAAAGAGCTTGAATTAA
AAATGGAGCGCCTTTCTAATAACTTGCGTTTTGAAGAAGCCCTCATTTATAGGGATAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTAGCCAAACTCTATGATTTGGATATTTTTGCTTTTTATAGTGGGAGCCATAAGGCAGT
GTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTTAATGGGTTTGACA
CTGATGAAGCGATGAAACAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTGATGCCTGAACAGATTTTATTGAAC
GCTTGCTCTAATGAAACGCTTAAAGAATTGCAAGATTTTATCTCTCATCAATACTCTAAAAAAATCGCTCTTAGCATTCC
TAAAAAAGGCGATAAGCTCGCTTTAATAGAAATCGCTATAAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
GTGAGGATCTGATTTTAGAAGAAGTGCGATCGCTCTTTCAATTAGAGTGCATGCCTTATAGGGTGGAAATCTTTGACACA
AGCCACCATGCCAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAATCATGAATTTCAAAAAAACTCCTATCGGCG
CTACCATTTAAAAGGCTCTAACGAATACACTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGATTTTAATAAAGAGC
CGCCGCCTAATTTGTGGGTGATCGATGGAGGGAGGGTGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGGGGTGCTAAAGACATTAT
CCACACCGCTAACGATACTTTTAAATTGCTCCCTAGCGACAAGCGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAAGGCATA
GGAGAAGCCAGCGTGAAAAAATTGTTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCTGTTTTAAAAAAACGAATCTAA

Domains

Predicted by InterproScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrB/uvrC motif (UVR)

(205-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

96.128

100

0.961