Detailed information NTG0919019

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: VNN51_RS01705
• Genome accession: NZ_CP141727
• Coordinates: 354550..357000 (-)
• Length: 816 a.a.
• NCBI ID: WP_279360560.1
• Uniprot ID: A0A9X4SAD0
• Organism: Lactococcus formosensis strain M20011502 FF20a2
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 349550..362000

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VNN51_RS01690 (VNN51_01690)	coaE	349730..350335 (-)	606	WP_165711447.1	dephospho-CoA kinase	-
VNN51_RS01695 (VNN51_01695)	pflB	351289..353622 (-)	2334	WP_003134012.1	formate C-acetyltransferase	-
VNN51_RS01700 (VNN51_01700)	raiA	353870..354427 (-)	558	WP_003134010.1	ribosome-associated translation inhibitor RaiA	-
VNN51_RS01705 (VNN51_01705)	clpC	354550..357000 (-)	2451	WP_279360560.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
VNN51_RS01710 (VNN51_01710)	-	356990..357442 (-)	453	WP_017368805.1	CtsR family transcriptional regulator	-
VNN51_RS01715 (VNN51_01715)	greA	357562..358035 (-)	474	WP_017369377.1	transcription elongation factor GreA	-
VNN51_RS01720 (VNN51_01720)	mltG	358061..359773 (-)	1713	WP_279360515.1	endolytic transglycosylase MltG	-
VNN51_RS01725 (VNN51_01725)	rpoE	359879..360439 (-)	561	WP_017369379.1	DNA-directed RNA polymerase subunit delta	-
VNN51_RS01730 (VNN51_01730)	-	360565..361077 (-)	513	WP_003135164.1	adenine phosphoribosyltransferase	-

Sequence

Protein

• Length: 816 a.a.
• Molecular weight: 91166.40 Da
• Isoelectric Point: 6.2967

>NTDB_id=919019 VNN51_RS01705 WP_279360560.1 354550..357000(-) (clpC) [Lactococcus formosensis strain M20011502 FF20a2]
MKFNEKDYTPQVIRVLKKSVDYAHKFNYAWVESSHLLAALAEVPASLAFTLLNSEKIDLEEMLIDIEDFSSQVKTKKSEI
KLSPRVETIIEQARALAQNNDKNRIGTEHLLYMLLANEAGFAGQLLREQNINIVNLRKKLEQKAYLRVPERRKAVTPASK
RNLSGKVSETTTTPTLDTVSTDLTKAAREGKLDPMIGREREVERLIHILSRRTKNNPVLVGEPGVGKSAIIEGFATRVAA
GNVPVGLRGSRIMALNMAMVVAGTKFRGEFEDRLTAIVDEVTHDKDVIVFIDELHTIIGAGGGMDSVNDASNILKPALAR
GEFQLIGATTYQEYQKYIEKDEALERRFARVNVEEPSEDETVAILQGLKEKFEAYHAVKFEEGTLERAVSLSNRYMPSRR
LPDKAIDLLDEAAAKVKITSKTNCTKLDELKAELKAEELRLQKAVVALDIVEAQEIEKDIEKLTHKIDNFTVSENDNPLV
EESDVYAVVSNLTGIPLQQMTKTESERLINLEKELHKRVVGQEEAISAVSRAIRRARSGIADTRRPLGSFMFLGPTGVGK
TELAKALAESVFGSEENMIRVDMSEFMEKFSTSRLIGAPPGYVGYDEGGQLTEQVRNKPYSVILLDEVEKAHPDIFNIML
QILDDGFVTDTKGRKVDFRNTIIIMTSNLGATAIRDDKTVGFGAKSISTDYAAMKARTMEELKKQYRPEFLNRIDETIVF
HSLTEKEIEQVVKIMSKSLVSRLKDQNIKVRFTSAALKVIADKGFDPEYGARPLRKALQREVEDTLSEQLLAGEIHPGDT
ISIGSSNKKIRISVID

Nucleotide

• Length: 2451 bp

>NTDB_id=919019 VNN51_RS01705 WP_279360560.1 354550..357000(-) (clpC) [Lactococcus formosensis strain M20011502 FF20a2]
ATGAAATTTAATGAAAAGGACTATACACCACAAGTCATAAGAGTGCTTAAGAAGTCTGTTGACTATGCGCATAAGTTTAA
CTACGCTTGGGTTGAAAGCTCGCACCTATTGGCTGCATTGGCTGAGGTTCCGGCTTCATTGGCATTTACGCTACTTAATT
CAGAAAAAATTGATTTGGAAGAAATGTTAATCGACATTGAAGATTTTTCAAGTCAAGTGAAGACGAAGAAATCAGAAATA
AAGCTTAGCCCAAGAGTTGAGACAATTATTGAGCAAGCACGTGCATTGGCTCAAAATAATGATAAAAACCGTATCGGGAC
AGAGCATCTCTTATATATGCTTTTAGCAAATGAAGCTGGCTTTGCAGGACAACTTTTACGTGAGCAAAACATCAATATCG
TTAATCTCCGCAAAAAGCTAGAGCAAAAAGCATATCTACGTGTACCAGAACGCCGTAAAGCGGTGACACCAGCTTCGAAA
AGAAACTTGTCAGGGAAAGTTTCCGAAACCACGACAACGCCTACTTTAGATACGGTATCGACAGATTTGACCAAAGCAGC
CCGTGAAGGCAAGCTTGATCCAATGATTGGAAGAGAGCGGGAAGTCGAACGCCTCATCCACATTCTGAGTCGTCGGACAA
AAAATAACCCTGTTCTTGTTGGTGAACCTGGTGTTGGTAAGTCAGCGATTATTGAAGGCTTTGCGACACGTGTGGCTGCA
GGGAATGTTCCTGTAGGTCTACGTGGCAGCCGTATTATGGCCTTGAACATGGCGATGGTTGTTGCGGGGACAAAATTCCG
TGGTGAATTTGAAGATCGTTTGACAGCCATCGTTGATGAAGTGACACATGATAAAGATGTGATCGTCTTTATCGATGAAC
TTCATACCATTATAGGTGCTGGTGGAGGTATGGACTCTGTTAACGATGCTTCTAACATCTTAAAACCTGCATTGGCACGG
GGTGAGTTTCAACTTATCGGGGCAACAACTTATCAAGAATATCAAAAATACATTGAAAAAGATGAAGCCCTAGAACGTCG
TTTTGCCCGTGTTAATGTTGAAGAACCATCAGAAGATGAAACAGTTGCAATCTTACAAGGGTTAAAAGAAAAATTTGAAG
CTTACCATGCGGTCAAATTTGAAGAGGGAACTTTGGAACGTGCTGTCAGCCTGAGTAATCGTTATATGCCAAGTCGTCGT
CTGCCTGATAAAGCAATTGATCTCCTTGATGAAGCCGCAGCCAAAGTTAAAATCACGAGTAAAACAAATTGCACCAAGCT
TGACGAATTAAAAGCAGAGTTAAAAGCAGAAGAGCTGAGATTACAAAAAGCAGTTGTAGCACTTGATATTGTTGAAGCAC
AGGAGATTGAAAAAGATATTGAAAAGTTAACGCATAAAATTGATAACTTTACAGTATCGGAAAATGATAATCCTTTGGTT
GAGGAAAGCGATGTTTATGCTGTCGTTTCCAACCTTACAGGAATCCCGCTCCAACAGATGACGAAAACAGAAAGTGAACG
TCTGATTAATCTAGAAAAAGAGCTACATAAGCGTGTAGTTGGTCAGGAAGAAGCGATATCGGCTGTTTCTCGTGCCATAA
GACGTGCACGTTCAGGTATCGCCGATACGAGACGTCCTTTGGGTTCATTTATGTTCCTTGGTCCGACAGGGGTTGGGAAG
ACAGAGCTTGCTAAGGCTTTAGCGGAAAGTGTTTTTGGAAGTGAAGAAAACATGATTCGCGTAGACATGAGTGAATTTAT
GGAAAAATTCTCGACATCACGCCTGATTGGAGCGCCTCCAGGCTACGTAGGTTATGATGAAGGGGGGCAACTGACAGAGC
AAGTCCGTAATAAGCCTTATTCTGTTATCCTTCTTGATGAAGTAGAAAAGGCCCATCCTGATATTTTCAATATTATGTTA
CAAATTCTAGATGATGGTTTCGTTACAGACACGAAGGGTCGTAAAGTTGATTTCCGTAATACCATCATCATTATGACATC
TAACCTTGGAGCAACAGCTATTCGTGATGATAAAACAGTTGGTTTTGGTGCTAAATCAATCTCAACAGATTATGCAGCTA
TGAAAGCGAGAACCATGGAAGAACTGAAGAAACAGTACCGTCCAGAATTTCTCAATCGTATCGATGAAACCATTGTCTTC
CATTCACTCACAGAAAAAGAGATTGAACAAGTCGTGAAAATTATGAGTAAATCTCTCGTATCACGCTTGAAAGATCAAAA
TATCAAAGTGAGATTTACATCTGCTGCACTAAAAGTTATTGCAGATAAAGGATTTGATCCTGAATATGGTGCCCGTCCGT
TACGTAAAGCCTTGCAACGTGAGGTTGAAGACACGCTTAGTGAGCAATTGCTTGCAGGTGAAATTCATCCGGGGGATACG
ATTTCTATTGGTTCTTCTAATAAAAAGATTAGAATAAGTGTTATTGATTGA

Domains

Predicted by InterproScan.

• ATPase family associated with various cellular activities (AAA) (AAA) (218-349)

• AAA lid domain (AAA_lid_9) (357-449)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (93-142)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (22-69)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (723-803)

• AAA domain (Cdc48 subfamily) (AAA_2) (545-716)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	70.798	99.877	0.707
clpC	Streptococcus thermophilus LMG 18311	48.636	100	0.502
clpC	Streptococcus thermophilus LMD-9	48.636	100	0.502
clpC	Streptococcus pneumoniae TIGR4	48.91	100	0.495
clpC	Streptococcus pneumoniae Rx1	48.789	100	0.494
clpC	Streptococcus pneumoniae D39	48.789	100	0.494
clpC	Streptococcus mutans UA159	47.01	100	0.482
clpC	Bacillus subtilis subsp. subtilis str. 168	48.696	98.652	0.48
clpE	Streptococcus mutans UA159	46.656	78.799	0.368