Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   VNN28_RS01375 Genome accession   NZ_CP141725
Coordinates   276964..278454 (-) Length   496 a.a.
NCBI ID   WP_338997729.1    Uniprot ID   -
Organism   Lactococcus formosensis strain M03102409 EE5d7     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 271964..283454
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VNN28_RS01360 (VNN28_01360) murD 272759..274120 (-) 1362 WP_338997726.1 UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase -
  VNN28_RS01365 (VNN28_01365) - 274259..274996 (-) 738 WP_338997727.1 amino acid ABC transporter ATP-binding protein -
  VNN28_RS01370 (VNN28_01370) - 274997..276568 (-) 1572 WP_338997728.1 ABC transporter permease subunit -
  VNN28_RS01375 (VNN28_01375) covS 276964..278454 (-) 1491 WP_338997729.1 HAMP domain-containing histidine kinase Regulator
  VNN28_RS01380 (VNN28_01380) covR 278542..279237 (-) 696 WP_017368870.1 response regulator transcription factor Regulator
  VNN28_RS01385 (VNN28_01385) - 279338..279889 (-) 552 WP_165711405.1 YceD family protein -
  VNN28_RS01390 (VNN28_01390) - 280107..280349 (-) 243 WP_003135050.1 type B 50S ribosomal protein L31 -
  VNN28_RS01395 (VNN28_01395) - 280461..282365 (-) 1905 WP_338997730.1 fructose-specific PTS transporter subunit EIIC -
  VNN28_RS01400 (VNN28_01400) pfkB 282399..283316 (-) 918 WP_338997731.1 1-phosphofructokinase -

Sequence

Protein


Download         Length: 496 a.a.        Molecular weight: 56924.84 Da        Isoelectric Point: 4.9835

>NTDB_id=918968 VNN28_RS01375 WP_338997729.1 276964..278454(-) (covS) [Lactococcus formosensis strain M03102409 EE5d7]
MVKFFDSKKKKTESLPERKRSIMLRWAFANTIFCFITFTIFTVLVYQLTITTFINSEKEDMMRALNNVEQSLSQSVNKLS
EENLANYLAYAKDYTASSQGRENELETLGSMIGSRKSFYVFDVGENLIYSTNSYGFPLRKDVGNSSQAVRTFGEYSGYLV
ERPVHSKKTGELIGYVQAFYDMSYYYSVRTKLLVALIILEIIALFIAQFVGYFMASRYIKPLEHLHDAITTRANNLKADF
KPVVIQTGDEIEELATVYNDMMIKLNDYVDQQKRFVSDVSHELRTPLAVLDGHLNLLNRWGKNDPEVLEESLQASIEEVS
TMRTMLEEMLALARLESIDFQDEDLICDPTEVSNFLKKNFLLIHPDLKLTVENDLPSGRLAHIYPNHYEQGLKILIDNAI
KYSPEDRQEVQIHLEEDDEYIITTVEDRGYGISQEDLKHVFERFFRADKARNRDIGGTGLGLSIIQRIVENYEGDVSVTS
VVGEGSKFTLKIPKIK

Nucleotide


Download         Length: 1491 bp        

>NTDB_id=918968 VNN28_RS01375 WP_338997729.1 276964..278454(-) (covS) [Lactococcus formosensis strain M03102409 EE5d7]
ATGGTAAAATTTTTTGATTCTAAGAAGAAAAAAACAGAAAGTCTTCCCGAGCGTAAGCGGAGCATCATGCTACGTTGGGC
ATTTGCAAATACGATTTTTTGTTTTATTACTTTCACTATTTTTACAGTATTGGTTTATCAACTAACGATAACTACTTTCA
TCAATTCTGAAAAAGAGGATATGATGAGGGCTTTAAATAATGTTGAACAAAGTCTGTCCCAATCGGTAAACAAACTGTCA
GAAGAAAATCTTGCGAATTATTTGGCTTATGCCAAAGACTACACAGCCTCCAGTCAGGGAAGAGAAAATGAACTTGAAAC
ACTAGGAAGTATGATTGGTTCAAGAAAGTCCTTTTATGTCTTCGATGTAGGTGAGAACCTGATTTACTCGACCAATTCGT
ATGGTTTTCCTCTAAGGAAAGATGTGGGTAATTCATCGCAAGCTGTACGTACATTTGGCGAATATTCTGGTTATTTGGTG
GAGCGACCTGTGCACTCCAAAAAAACGGGTGAACTGATCGGCTATGTACAGGCTTTTTATGATATGAGCTATTATTATAG
TGTGCGTACAAAGCTACTTGTTGCCTTGATTATCTTAGAAATTATAGCTCTCTTTATAGCTCAGTTTGTTGGTTACTTTA
TGGCGAGTCGCTATATCAAGCCTTTGGAACATTTGCACGATGCAATCACTACACGTGCCAATAATTTGAAGGCAGATTTC
AAACCTGTCGTTATTCAGACGGGGGATGAAATTGAGGAACTTGCAACAGTTTATAATGATATGATGATCAAGCTTAATGA
TTACGTTGATCAGCAGAAACGTTTTGTTTCCGATGTCAGTCATGAGTTACGGACGCCACTTGCAGTTTTGGATGGGCATT
TGAATCTCTTGAATCGTTGGGGGAAAAATGATCCTGAAGTGCTTGAGGAGTCTTTACAGGCCAGTATAGAAGAAGTTAGT
ACGATGAGAACGATGTTGGAAGAGATGCTCGCATTGGCGCGTCTTGAAAGCATTGATTTTCAAGATGAAGACCTAATCTG
TGATCCAACAGAAGTTTCGAATTTTCTTAAGAAAAATTTTCTACTCATCCATCCTGATTTAAAGTTAACTGTTGAAAATG
ACTTGCCATCAGGAAGATTAGCACATATATATCCCAACCATTATGAGCAAGGTTTGAAAATATTGATTGATAATGCGATA
AAATACTCGCCTGAAGATCGTCAAGAAGTCCAGATACATCTTGAAGAAGATGATGAATATATCATTACAACTGTGGAGGA
CCGTGGTTATGGTATTAGCCAAGAAGATTTAAAACATGTATTTGAACGTTTCTTCCGTGCGGATAAAGCACGAAATCGAG
ATATAGGAGGAACTGGGCTTGGGCTATCTATTATTCAACGTATAGTGGAGAACTATGAGGGAGATGTTAGCGTGACTTCC
GTTGTAGGAGAGGGTTCAAAATTTACTTTAAAAATTCCTAAGATTAAATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(272-337)

ArlS sensor domain (ArlS_N)

(52-190)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(389-494)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Lactococcus lactis subsp. lactis strain DGCC12653

55.734

100

0.558