Detailed information NTG0918792

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: VNN46_RS01770
• Genome accession: NZ_CP141719
• Coordinates: 373309..375759 (-)
• Length: 816 a.a.
• NCBI ID: WP_338963045.1
• Uniprot ID: -
• Organism: Lactococcus garvieae strain CAHFS22LA20.5H7
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 368309..380759

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VNN46_RS01760 (VNN46_01760)	pflB	370047..372380 (-)	2334	WP_003134012.1	formate C-acetyltransferase	-
VNN46_RS01765 (VNN46_01765)	hpf	372628..373185 (-)	558	WP_003134010.1	ribosome hibernation-promoting factor, HPF/YfiA family	-
VNN46_RS01770 (VNN46_01770)	clpC	373309..375759 (-)	2451	WP_338963045.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
VNN46_RS01775 (VNN46_01775)	-	375749..376201 (-)	453	WP_003134006.1	CtsR family transcriptional regulator	-
VNN46_RS01780 (VNN46_01780)	greA	376323..376796 (-)	474	WP_003134005.1	transcription elongation factor GreA	-
VNN46_RS01785 (VNN46_01785)	mltG	376821..378536 (-)	1716	WP_338962233.1	endolytic transglycosylase MltG	-
VNN46_RS01790 (VNN46_01790)	rpoE	378642..379202 (-)	561	WP_003134001.1	DNA-directed RNA polymerase subunit delta	-
VNN46_RS01795 (VNN46_01795)	-	379340..379852 (-)	513	WP_003134000.1	adenine phosphoribosyltransferase	-

Sequence

Protein

• Length: 816 a.a.
• Molecular weight: 91123.38 Da
• Isoelectric Point: 6.1748

>NTDB_id=918792 VNN46_RS01770 WP_338963045.1 373309..375759(-) (clpC) [Lactococcus garvieae strain CAHFS22LA20.5H7]
MKFNEKDFTPQVVRVLEKSVDYAHKFNYAWVESSHLLAALAEVPASLAFTLLNSEKIDLEEMLIDIEDFSSQMKTKKSDI
KLSPRVETIIEQARALAQNNDKNRIGTEHLLYMLLANEASFAGQLLREQNINIVNLRKKLEQKAYLRVPERRKAVTPASK
RNLSGKVSETTTTPTLDTVSTDLTKAAREGKLDPMIGREREVERLIHILSRRTKNNPVLVGEPGVGKSAIIEGFATRVAA
GNVPVGLRGSRIMALNMAMVVAGTKFRGEFEDRLTAIVDEVTHDKDVIVFIDELHTIIGAGGGMDSVNDASNILKPALAR
GEFQLIGATTYQEYQKYIEKDEALERRFARVNVEEPSEKETVAILQGLKEKFEAYHAVKFEEGALERAVSLSNRYMPSRR
LPDKAIDLLDEAAAKVKITSKTNYTKLDELKAELKAEELKLQQAVVALDIVEAQGIEKDIERLTHKIDNFTVSENDNPLV
EESDIYAVVSNLTGIPLQQMTKTESERLINLEKELHKRVVGQEEAISAVSRAIRRARSGIADTRRPLGSFMFLGPTGVGK
TELAKALAESVFGSEENMIRVDMSEFMEKFSTSRLIGAPPGYVGYDEGGQLTEQVRNKPYSVILLDEVEKAHPDIFNIML
QILDDGFVTDTKGRKVDFRNTIIIMTSNLGATAIRDDKTVGFGAKSISTDYAAMKARIMEELKKQYRPEFLNRIDETIVF
HSLTEKEIEQVVKIMSKSLVSRLKDQNITVKFTPAALKVIADKGFDPEYGARPLRKALQREVEDTLSEQLLAGDIHPGDT
ISIGSSNKKIRISVID

Nucleotide

• Length: 2451 bp

>NTDB_id=918792 VNN46_RS01770 WP_338963045.1 373309..375759(-) (clpC) [Lactococcus garvieae strain CAHFS22LA20.5H7]
ATGAAATTTAATGAAAAGGACTTTACACCACAAGTTGTTAGAGTGCTCGAGAAGTCTGTCGACTATGCGCATAAGTTTAA
CTACGCTTGGGTAGAAAGCTCGCACCTATTGGCTGCCTTGGCTGAGGTTCCGGCTTCATTGGCATTTACGCTACTTAATT
CAGAAAAGATTGATTTGGAAGAGATGTTAATCGACATCGAAGATTTTTCAAGTCAAATGAAGACAAAAAAATCAGACATA
AAGCTTAGCCCAAGAGTTGAAACGATTATTGAGCAAGCCCGAGCATTGGCTCAAAATAACGATAAAAACCGTATTGGGAC
AGAGCATCTCTTGTATATGCTGTTGGCAAATGAAGCCAGCTTTGCAGGACAACTTTTACGTGAGCAAAACATTAATATCG
TTAACCTCCGTAAAAAGTTAGAGCAAAAAGCATATTTACGAGTGCCAGAACGCCGTAAAGCGGTGACCCCTGCTTCGAAA
AGAAACCTGTCGGGGAAGGTGTCCGAAACAACAACAACACCTACTTTAGATACAGTCTCGACAGATTTGACAAAAGCAGC
GCGTGAAGGCAAGCTTGATCCAATGATTGGGAGAGAGCGTGAAGTCGAACGTCTTATCCATATCTTGAGTCGCCGAACAA
AGAATAATCCCGTTCTTGTTGGTGAACCAGGCGTTGGTAAGTCAGCCATTATTGAGGGCTTTGCCACACGTGTGGCTGCA
GGAAATGTTCCTGTAGGTTTACGCGGCAGTCGTATCATGGCCTTGAATATGGCGATGGTCGTAGCGGGGACGAAGTTCCG
TGGTGAATTTGAAGATCGTTTGACAGCTATTGTGGATGAAGTGACACATGATAAAGATGTTATCGTCTTTATCGATGAAC
TCCATACTATTATTGGTGCTGGGGGAGGCATGGACTCTGTCAATGATGCCTCAAACATTTTAAAACCCGCATTAGCACGT
GGCGAGTTTCAACTTATTGGTGCTACTACTTATCAAGAATATCAAAAATATATTGAAAAAGATGAAGCTCTGGAGCGCCG
TTTTGCCCGTGTCAATGTCGAAGAACCCTCAGAAAAAGAAACGGTTGCGATTTTACAAGGCTTGAAAGAAAAATTTGAAG
CTTACCATGCGGTTAAATTTGAAGAAGGGGCTTTGGAGCGTGCCGTTAGCTTGAGTAATCGCTACATGCCAAGTCGTCGT
CTGCCAGACAAAGCCATTGATCTTCTTGATGAAGCAGCGGCCAAAGTTAAAATCACGAGTAAAACAAATTACACCAAGCT
AGACGAGTTAAAAGCAGAATTAAAAGCGGAAGAGCTGAAATTACAACAAGCAGTTGTTGCTCTTGATATTGTTGAAGCAC
AAGGAATTGAAAAAGATATTGAAAGATTAACACACAAAATTGATAATTTTACAGTATCGGAAAATGATAATCCTTTGGTC
GAAGAAAGCGATATTTATGCTGTTGTTTCTAACCTTACAGGAATTCCGCTCCAACAAATGACGAAAACAGAAAGTGAACG
TCTGATTAACTTAGAAAAAGAGTTACATAAACGTGTGGTCGGACAGGAAGAAGCGATTTCGGCTGTTTCTCGTGCTATAA
GACGTGCGCGTTCAGGTATTGCTGATACGAGACGTCCTCTGGGCTCATTTATGTTCCTTGGTCCGACAGGGGTGGGGAAA
ACAGAGCTTGCTAAAGCTTTAGCGGAAAGTGTCTTTGGGAGTGAAGAGAACATGATTCGCGTAGACATGAGTGAATTTAT
GGAAAAATTCTCGACATCGCGTCTTATCGGAGCACCTCCAGGGTATGTAGGTTATGACGAAGGGGGGCAATTGACAGAAC
AAGTCCGTAATAAGCCTTATTCTGTTATTCTCCTTGATGAAGTTGAAAAAGCCCATCCTGATATTTTCAATATCATGTTG
CAAATTTTGGATGACGGTTTCGTTACAGATACCAAAGGGCGGAAGGTTGATTTCCGAAATACAATCATCATTATGACATC
CAACTTAGGCGCAACGGCTATTCGTGATGATAAAACGGTTGGTTTTGGGGCTAAATCAATTTCAACAGATTATGCAGCCA
TGAAAGCAAGAATTATGGAAGAACTGAAGAAACAGTACCGTCCAGAATTTCTTAACCGTATCGATGAAACCATCGTTTTC
CATTCACTGACTGAAAAAGAGATTGAACAAGTCGTGAAAATCATGAGTAAATCTCTTGTATCACGTTTGAAAGATCAAAA
TATTACAGTGAAATTTACCCCTGCTGCTTTGAAAGTTATTGCTGATAAAGGATTTGATCCTGAGTATGGTGCACGTCCGT
TGCGTAAAGCGCTACAACGGGAGGTTGAAGACACGCTCAGTGAGCAATTGCTTGCAGGCGACATTCATCCGGGGGATACG
ATTTCGATTGGGTCTTCTAATAAAAAGATTAGAATAAGTGTTATTGATTGA

Domains

Predicted by InterproScan.

• AAA lid domain (AAA_lid_9) (357-445)

• ATPase family associated with various cellular activities (AAA) (AAA) (218-349)

• AAA domain (Cdc48 subfamily) (AAA_2) (545-716)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (723-803)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (22-69)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (93-142)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	70.552	99.877	0.705
clpC	Streptococcus thermophilus LMG 18311	49.819	100	0.505
clpC	Streptococcus thermophilus LMD-9	49.819	100	0.505
clpC	Streptococcus pneumoniae TIGR4	49.395	100	0.5
clpC	Streptococcus pneumoniae Rx1	49.274	100	0.499
clpC	Streptococcus pneumoniae D39	49.274	100	0.499
clpC	Streptococcus mutans UA159	47.608	100	0.488
clpC	Bacillus subtilis subsp. subtilis str. 168	48.31	97.917	0.473
clpE	Streptococcus mutans UA159	46.875	78.431	0.368