Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   VNN46_RS01345 Genome accession   NZ_CP141719
Coordinates   273700..275190 (-) Length   496 a.a.
NCBI ID   WP_014024351.1    Uniprot ID   A0AA46TWW1
Organism   Lactococcus garvieae strain CAHFS22LA20.5H7     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 268700..280190
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VNN46_RS01330 (VNN46_01330) murD 269494..270855 (-) 1362 WP_141921009.1 UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase -
  VNN46_RS01335 (VNN46_01335) - 270994..271731 (-) 738 WP_338962109.1 amino acid ABC transporter ATP-binding protein -
  VNN46_RS01340 (VNN46_01340) - 271732..273303 (-) 1572 WP_004259090.1 ABC transporter permease subunit -
  VNN46_RS01345 (VNN46_01345) covS 273700..275190 (-) 1491 WP_014024351.1 HAMP domain-containing histidine kinase Regulator
  VNN46_RS01350 (VNN46_01350) covR 275279..275974 (-) 696 WP_004259096.1 response regulator transcription factor Regulator
  VNN46_RS01355 (VNN46_01355) - 276076..276627 (-) 552 WP_023889673.1 DUF177 domain-containing protein -
  VNN46_RS01360 (VNN46_01360) - 276844..277086 (-) 243 WP_003135050.1 type B 50S ribosomal protein L31 -
  VNN46_RS01365 (VNN46_01365) - 277198..279102 (-) 1905 WP_014024348.1 fructose-specific PTS transporter subunit EIIC -
  VNN46_RS01370 (VNN46_01370) pfkB 279117..280043 (-) 927 WP_004259111.1 1-phosphofructokinase -

Sequence

Protein


Download         Length: 496 a.a.        Molecular weight: 56753.73 Da        Isoelectric Point: 5.1966

>NTDB_id=918786 VNN46_RS01345 WP_014024351.1 273700..275190(-) (covS) [Lactococcus garvieae strain CAHFS22LA20.5H7]
MVKFFDSKKKKTESLPERKRSIMLRWAFANTIFCFITFTIFTVLVYQLTITTFINSEKEDMMKALDNVEQSLSQSESTLS
EENLANYLAYAKDYTASSQGKENELETLGSMIGSRKSFYVFDVGENLIYSTNSHGFPLKKDVGDGTHAVRTFGEYSGYLV
ERPVYSNKTGKLIGYVQAFYDMSYYYSVRTKLLIALIILEIIALFIAQFVGYFMASRYIKPLERLHDAITTRANNLKADF
KPVVIQTGDEIEELATVYNDMMIKLNDYVDQQKRFVSDVSHELRTPLAVLDGHLNLLNRWGKNDPEVLEESLQASIEEVS
TMRTMLEEMLALARLENIDFQDEDLICDPTEVSNFLKKNFLLIHADLSLTVENNLSPGRLAHIYPNHYEQGLKILIDNAI
KYSPKDRQEVKIHLEEDDKYIITTVEDHGYGISQEDLKHVFERFFRADKARNRDIGGTGLGLSIIQRIVENYDGDVSVTS
VVGEGSKFTLKIPKIK

Nucleotide


Download         Length: 1491 bp        

>NTDB_id=918786 VNN46_RS01345 WP_014024351.1 273700..275190(-) (covS) [Lactococcus garvieae strain CAHFS22LA20.5H7]
ATGGTAAAATTTTTTGATTCGAAGAAGAAAAAAACAGAAAGTCTTCCCGAGCGTAAGCGAAGCATCATGCTACGTTGGGC
ATTTGCAAATACGATTTTTTGTTTTATTACCTTCACTATTTTTACAGTATTGGTTTACCAATTGACCATTACAACCTTCA
TCAATTCTGAAAAAGAGGATATGATGAAAGCTCTGGATAATGTTGAGCAAAGTTTGTCCCAATCGGAAAGCACACTGTCG
GAAGAAAATCTGGCGAATTATTTGGCTTATGCCAAAGACTATACAGCCTCCAGTCAGGGAAAAGAAAATGAGCTAGAAAC
ACTTGGAAGTATGATTGGCTCTAGGAAGTCCTTTTATGTTTTTGACGTCGGTGAAAATTTGATTTACTCGACCAATTCGC
ATGGTTTCCCTCTAAAAAAAGACGTGGGGGATGGCACTCATGCTGTACGTACATTTGGTGAATATTCTGGTTATTTGGTC
GAACGACCGGTTTATTCTAATAAAACAGGTAAGCTGATTGGCTATGTGCAGGCTTTCTATGATATGAGTTATTATTATAG
CGTGCGAACAAAGTTACTGATTGCCCTGATTATCTTAGAGATTATTGCTCTCTTTATCGCTCAGTTTGTCGGTTATTTTA
TGGCGAGTCGTTACATCAAGCCTCTGGAACGGTTGCACGATGCGATTACTACACGTGCCAATAACTTGAAGGCGGATTTC
AAACCTGTAGTGATTCAAACAGGTGATGAAATTGAAGAACTGGCGACTGTTTATAATGACATGATGATCAAGCTTAACGA
TTATGTTGATCAGCAGAAACGTTTTGTTTCTGATGTCAGTCACGAGTTACGTACGCCACTTGCGGTTTTGGATGGTCATT
TGAATCTCTTGAACCGTTGGGGGAAAAACGATCCCGAGGTGCTTGAGGAGTCTTTACAGGCCAGTATAGAAGAAGTGAGT
ACGATGAGAACGATGTTGGAAGAGATGCTTGCATTGGCCCGTCTTGAAAACATTGATTTTCAAGATGAAGACCTTATCTG
TGATCCAACAGAAGTTTCTAATTTCCTTAAGAAAAACTTCCTACTTATTCATGCTGATTTAAGCTTAACTGTGGAAAATA
ACTTGTCACCGGGAAGATTGGCTCATATCTACCCGAACCATTATGAACAAGGCTTAAAAATTTTGATTGATAATGCGATA
AAATACTCTCCTAAAGATCGCCAAGAAGTGAAAATCCATCTAGAAGAAGATGATAAATACATTATCACTACGGTTGAGGA
TCATGGCTATGGCATTAGTCAGGAAGATTTAAAACATGTCTTTGAGCGTTTCTTCCGTGCTGATAAAGCGCGAAATCGGG
ATATAGGAGGCACTGGGCTTGGACTGTCTATTATCCAACGCATAGTGGAAAACTATGATGGGGATGTCAGTGTGACTTCT
GTTGTAGGTGAGGGATCGAAATTCACTTTAAAAATTCCTAAGATTAAATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(272-337)

ArlS sensor domain (ArlS_N)

(52-190)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(389-494)

HAMP domain (HAMP)

(214-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Lactococcus lactis subsp. lactis strain DGCC12653

55.936

100

0.56