Detailed information    

insolico Bioinformatically predicted

Overview

Name   sepM   Type   Regulator
Locus tag   VNN36_RS04880 Genome accession   NZ_CP141717
Coordinates   949380..950423 (+) Length   347 a.a.
NCBI ID   WP_074751408.1    Uniprot ID   A0A1I4HNE3
Organism   Lactococcus garvieae strain R22-8     
Function   processing of CSP (predicted from homology)   
Competence regulation

Genomic Context

Location: 944380..955423
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VNN36_RS04865 (VNN36_04865) - 946923..948269 (+) 1347 WP_339014311.1 glucose-6-phosphate isomerase -
  VNN36_RS04870 (VNN36_04870) rsmD 948364..948903 (+) 540 WP_014025494.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  VNN36_RS04875 (VNN36_04875) coaD 948893..949390 (+) 498 WP_339014314.1 pantetheine-phosphate adenylyltransferase -
  VNN36_RS04880 (VNN36_04880) sepM 949380..950423 (+) 1044 WP_074751408.1 SepM family pheromone-processing serine protease Regulator
  VNN36_RS04885 (VNN36_04885) adhE 950453..953146 (-) 2694 WP_339014316.1 bifunctional acetaldehyde-CoA/alcohol dehydrogenase -
  VNN36_RS04890 (VNN36_04890) - 953301..954341 (-) 1041 WP_339014318.1 lactonase family protein -
  VNN36_RS04895 (VNN36_04895) rpsB 954614..955387 (+) 774 WP_003133158.1 30S ribosomal protein S2 -

Sequence

Protein


Download         Length: 347 a.a.        Molecular weight: 37830.13 Da        Isoelectric Point: 6.9825

>NTDB_id=918767 VNN36_RS04880 WP_074751408.1 949380..950423(+) (sepM) [Lactococcus garvieae strain R22-8]
MKNEKIKKHKKLKLFFAIALPLLIVVGLFFPLPYYIEQPGGTIPVNQMVDVAGKKDEHKGNFYLTTVEMVRANAASMLYS
KSNSFATILSSEEMTGGMTNQQFDLVNQFYMQTAQNTAVYQAFKLAGKPYEMKYQGVYVLSITEDSTFKNDLQLSDTITA
VNGHTFKSSTEMIDYVSQQKVGDEVTIKYTRVDGSNHEATGKYIKLSNGKTGIGIGLVDHTQVVTDPKVKIDAGSIGGPS
AGMMFTLEIYSQITGKDLRQGREIAGTGTINEDGSIGQIGGVDKKVATASNSGAKIFLCPDETEEQAKASGTTNNYTDAL
AAAKKLNTDMKIVPVKTIQDALDYLEK

Nucleotide


Download         Length: 1044 bp        

>NTDB_id=918767 VNN36_RS04880 WP_074751408.1 949380..950423(+) (sepM) [Lactococcus garvieae strain R22-8]
ATGAAAAATGAAAAAATAAAAAAGCATAAAAAACTAAAGCTATTCTTTGCCATCGCGTTACCGCTTCTTATTGTAGTGGG
TTTATTCTTCCCCTTACCTTACTATATCGAGCAGCCCGGAGGAACCATTCCAGTTAATCAGATGGTCGATGTTGCGGGAA
AGAAAGATGAACATAAAGGCAATTTTTATTTAACGACCGTTGAAATGGTGCGGGCCAATGCCGCAAGTATGCTTTATTCC
AAGTCGAACTCTTTTGCCACTATTTTGAGTAGTGAAGAGATGACGGGTGGGATGACCAATCAGCAATTTGATTTGGTCAA
CCAGTTCTATATGCAGACCGCGCAGAATACAGCTGTTTATCAGGCCTTTAAGTTGGCAGGGAAACCTTATGAGATGAAGT
ATCAAGGGGTCTACGTTTTGAGTATCACTGAGGATTCGACATTTAAAAATGACTTGCAACTTTCGGATACGATAACGGCA
GTTAATGGCCACACTTTCAAATCTTCAACTGAGATGATTGACTATGTGTCTCAACAAAAAGTTGGAGATGAGGTGACCAT
CAAGTACACACGGGTGGATGGCAGCAACCATGAAGCCACAGGCAAGTACATTAAGTTGAGTAATGGTAAAACAGGGATTG
GCATTGGTTTAGTAGATCATACACAGGTTGTGACAGACCCTAAAGTTAAAATCGACGCCGGAAGCATTGGCGGGCCAAGT
GCTGGGATGATGTTTACCTTGGAGATATATAGCCAAATCACAGGCAAAGATTTACGTCAAGGACGCGAAATTGCAGGTAC
TGGAACGATCAATGAAGATGGCAGCATCGGGCAAATAGGTGGCGTTGATAAAAAAGTTGCTACAGCAAGCAATTCGGGCG
CTAAAATTTTCCTTTGCCCGGATGAAACGGAAGAACAGGCAAAGGCTTCTGGTACAACAAATAACTATACAGATGCGCTT
GCGGCAGCTAAAAAGTTGAATACAGATATGAAAATCGTACCTGTAAAGACGATCCAAGATGCACTAGACTATCTCGAAAA
ATAA

Domains

Predicted by InterproScan.

Lon protease (S16) C-terminal proteolytic domain (Lon_C)

(229-308)

PDZ domain (PDZ_2)

(134-195)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1I4HNE3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sepM Streptococcus mutans UA159

49.28

100

0.493