Detailed information NTG0918749

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: VNN36_RS02055
• Genome accession: NZ_CP141717
• Coordinates: 413235..415685 (-)
• Length: 816 a.a.
• NCBI ID: WP_339014483.1
• Uniprot ID: -
• Organism: Lactococcus garvieae strain R22-8
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 408235..420685

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VNN36_RS02040 (VNN36_02040)	coaE	409136..409741 (-)	606	WP_339013769.1	dephospho-CoA kinase	-
VNN36_RS02045 (VNN36_02045)	pflB	409973..412306 (-)	2334	WP_003134012.1	formate C-acetyltransferase	-
VNN36_RS02050 (VNN36_02050)	raiA	412554..413111 (-)	558	WP_003134010.1	ribosome-associated translation inhibitor RaiA	-
VNN36_RS02055 (VNN36_02055)	clpC	413235..415685 (-)	2451	WP_339014483.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
VNN36_RS02060 (VNN36_02060)	-	415675..416127 (-)	453	WP_003134006.1	CtsR family transcriptional regulator	-
VNN36_RS02065 (VNN36_02065)	greA	416249..416722 (-)	474	WP_003134005.1	transcription elongation factor GreA	-
VNN36_RS02070 (VNN36_02070)	mltG	416747..418462 (-)	1716	WP_339013772.1	endolytic transglycosylase MltG	-
VNN36_RS02075 (VNN36_02075)	rpoE	418568..419128 (-)	561	WP_003134001.1	DNA-directed RNA polymerase subunit delta	-
VNN36_RS02080 (VNN36_02080)	-	419265..419777 (-)	513	WP_003134000.1	adenine phosphoribosyltransferase	-

Sequence

Protein

• Length: 816 a.a.
• Molecular weight: 91105.34 Da
• Isoelectric Point: 6.1755

>NTDB_id=918749 VNN36_RS02055 WP_339014483.1 413235..415685(-) (clpC) [Lactococcus garvieae strain R22-8]
MKFNEKDFTPQVVRVLEKSVDYAHKFNYAWVESSHLLAALAEVPASLAFTLLNSEKIDLEEMLIDIEDFSSQVKTKKSEI
KLSPRVETIIEQARALAQNNDKNRIGTEHLLYMLLANEASFAGQLLREQNINIVNLRKKLEQKAYLRVPERRKAVTPASK
RNLSGKVSETTTTPTLDTVSTDLTKAAREGKLDPMIGREREVERLIHILSRRTKNNPVLVGEPGVGKSAIIEGFATRVAA
GNVPVGLRGSRIMALNMAMVVAGTKFRGEFEDRLTAIVDEVTHDKDVIVFIDELHTIIGAGGGMDSVNDASNILKPALAR
GEFQLIGATTYQEYQKYIEKDEALERRFARVNVEEPSEKETVAILQGLKEKFEAYHAVKFEEGALERAVSLSNRYMPSRR
LPDKAIDLLDEAAAKVKITSKTNYTKLDELKAELKAEELKLQQAVVALDIVEAQGIEKDIERVTHKIDNFTVSENDNPLV
EESDIYAVVSNLTGIPLQQMTKTESERLINLEKELHKRVVGQEEAISAVSRAIRRARSGIADTRRPLGSFMFLGPTGVGK
TELAKALAESVFGSEENMIRVDMSEFMEKFSTSRLIGAPPGYVGYDEGGQLTEQVRNKPYSVILLDEVEKAHPDIFNIML
QILDDGFVTDTKGRKVDFRNTIIIMTSNLGATAIRDDKTVGFGAKSISTDYAAMKARIMEELKKQYRPEFLNRIDETIVF
HSLTEKEIEQVVKIMSKSLVSRLKDQNITVKFTPAALKVIADKGFDPEYGARPLRKALQREVEDTLSEQLLAGEIHPGDT
ISIGSSNKKIRISVID

Nucleotide

• Length: 2451 bp

>NTDB_id=918749 VNN36_RS02055 WP_339014483.1 413235..415685(-) (clpC) [Lactococcus garvieae strain R22-8]
ATGAAATTTAATGAAAAGGACTTTACACCACAAGTTGTTAGAGTGCTTGAGAAGTCTGTCGACTATGCGCATAAGTTTAA
CTACGCTTGGGTAGAAAGCTCACACCTATTGGCTGCCCTGGCTGAAGTTCCGGCTTCATTGGCATTTACGCTACTTAATT
CAGAAAAGATTGATTTGGAAGAGATGTTAATCGACATCGAAGATTTTTCAAGTCAAGTGAAGACAAAAAAATCAGAAATA
AAGCTTAGCCCAAGAGTTGAAACGATTATTGAGCAAGCCCGAGCATTGGCTCAAAATAACGATAAAAATCGTATTGGGAC
GGAACATCTCTTGTATATGCTGTTGGCAAATGAAGCCAGCTTTGCAGGACAACTTTTACGTGAGCAAAACATTAATATCG
TTAACCTCCGTAAAAAGTTAGAGCAAAAAGCATATTTACGAGTGCCAGAACGCCGTAAAGCGGTGACCCCAGCTTCGAAA
AGAAACCTGTCGGGGAAGGTGTCCGAAACAACAACAACACCTACTTTAGATACAGTCTCGACAGATTTGACAAAAGCAGC
GCGTGAAGGCAAGCTTGATCCAATGATTGGGAGAGAGCGTGAAGTCGAACGTCTTATCCATATTTTGAGTCGCCGAACAA
AGAATAATCCCGTTCTTGTTGGTGAACCAGGCGTTGGTAAGTCAGCCATTATTGAAGGCTTTGCGACACGTGTGGCTGCA
GGAAATGTTCCTGTAGGTTTACGCGGCAGTCGTATCATGGCCTTGAATATGGCGATGGTTGTAGCGGGGACGAAGTTCCG
TGGTGAATTTGAAGATCGTTTGACAGCTATTGTGGATGAAGTGACACATGATAAAGATGTTATCGTCTTTATCGATGAAC
TCCATACTATTATTGGTGCTGGGGGAGGCATGGACTCTGTCAATGATGCCTCAAACATTTTAAAACCCGCATTAGCACGT
GGCGAGTTTCAACTTATTGGTGCTACCACTTATCAAGAATATCAAAAATATATTGAAAAAGATGAAGCTCTGGAGCGCCG
TTTTGCCCGTGTCAATGTCGAAGAACCCTCAGAAAAAGAAACGGTTGCGATTTTACAAGGTTTGAAAGAAAAATTTGAAG
CTTACCATGCGGTTAAATTTGAAGAAGGGGCTTTGGAGCGTGCCGTTAGCTTGAGTAATCGCTACATGCCAAGTCGTCGT
CTGCCAGACAAAGCCATTGATCTTCTTGATGAAGCAGCGGCCAAAGTTAAAATCACGAGTAAAACAAATTACACCAAGCT
AGACGAGTTAAAAGCAGAATTAAAAGCGGAAGAGCTGAAATTACAACAAGCAGTTGTTGCTCTTGATATTGTTGAAGCAC
AAGGAATTGAAAAAGATATTGAAAGAGTAACACACAAAATTGATAATTTTACAGTATCGGAAAATGATAATCCTTTGGTC
GAAGAAAGCGATATTTATGCTGTTGTTTCTAACCTTACAGGAATTCCGCTCCAACAAATGACGAAAACAGAAAGTGAACG
TCTGATTAACTTAGAAAAAGAGTTACATAAACGTGTGGTCGGACAGGAAGAAGCGATTTCGGCTGTTTCTCGTGCTATAA
GACGTGCGCGTTCAGGTATTGCTGATACGAGACGTCCTCTGGGCTCATTTATGTTCCTTGGTCCGACAGGGGTGGGGAAA
ACAGAGCTTGCTAAAGCTTTAGCGGAAAGTGTCTTTGGGAGTGAAGAGAACATGATTCGCGTAGACATGAGTGAATTTAT
GGAAAAATTCTCGACATCGCGTCTTATCGGAGCACCTCCAGGGTATGTAGGTTACGATGAAGGGGGACAATTGACAGAGC
AAGTCCGTAATAAGCCTTATTCTGTTATTCTCCTTGATGAAGTTGAAAAAGCCCATCCTGATATTTTCAATATCATGTTG
CAAATTTTGGATGACGGTTTCGTTACAGATACCAAAGGGCGAAAAGTTGATTTCCGAAATACAATCATTATTATGACATC
TAACTTAGGCGCAACGGCTATTCGTGATGATAAAACGGTTGGTTTTGGGGCTAAATCAATTTCAACAGATTATGCAGCCA
TGAAAGCAAGAATTATGGAAGAACTGAAGAAACAGTACCGTCCAGAATTTCTTAACCGTATCGATGAAACCATCGTTTTC
CATTCACTGACTGAAAAAGAGATTGAACAAGTCGTGAAAATCATGAGTAAATCTCTTGTATCACGTTTGAAAGATCAAAA
TATTACAGTGAAATTTACCCCTGCTGCCTTGAAAGTTATTGCTGATAAAGGATTTGATCCTGAGTATGGTGCACGTCCGT
TGCGTAAAGCGCTACAACGGGAGGTTGAAGACACGCTCAGTGAGCAATTGCTTGCAGGCGAAATTCATCCGGGGGATACG
ATTTCGATTGGGTCTTCTAATAAAAAGATTAGAATAAGTGTTATTGATTGA

Domains

Predicted by InterproScan.

• ATPase family associated with various cellular activities (AAA) (AAA) (218-349)

• AAA domain (Cdc48 subfamily) (AAA_2) (545-716)

• AAA lid domain (AAA_lid_9) (357-445)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (723-803)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (22-69)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (93-142)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	70.798	99.877	0.707
clpC	Streptococcus thermophilus LMG 18311	49.94	100	0.506
clpC	Streptococcus thermophilus LMD-9	49.94	100	0.506
clpC	Streptococcus pneumoniae TIGR4	49.274	100	0.499
clpC	Streptococcus pneumoniae Rx1	49.153	100	0.498
clpC	Streptococcus pneumoniae D39	49.153	100	0.498
clpC	Streptococcus mutans UA159	47.488	100	0.487
clpC	Bacillus subtilis subsp. subtilis str. 168	48.185	97.917	0.472
clpE	Streptococcus mutans UA159	46.875	78.431	0.368