Detailed information NTG0918742

Bioinformatically predicted

Overview

• Name: covS
• Type: Regulator
• Locus tag: VNN36_RS01650
• Genome accession: NZ_CP141717
• Coordinates: 323210..324700 (-)
• Length: 496 a.a.
• NCBI ID: WP_339013680.1
• Uniprot ID: -
• Organism: Lactococcus garvieae strain R22-8
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 318210..329700

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VNN36_RS01635 (VNN36_01635)	murD	319004..320365 (-)	1362	WP_339013675.1	UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase	-
VNN36_RS01640 (VNN36_01640)	-	320504..321241 (-)	738	WP_339013678.1	amino acid ABC transporter ATP-binding protein	-
VNN36_RS01645 (VNN36_01645)	-	321242..322813 (-)	1572	WP_004259090.1	ABC transporter permease subunit	-
VNN36_RS01650 (VNN36_01650)	covS	323210..324700 (-)	1491	WP_339013680.1	HAMP domain-containing histidine kinase	Regulator
VNN36_RS01655 (VNN36_01655)	covR	324789..325484 (-)	696	WP_004259096.1	response regulator transcription factor	Regulator
VNN36_RS01660 (VNN36_01660)	-	325586..326137 (-)	552	WP_339013683.1	YceD family protein	-
VNN36_RS01665 (VNN36_01665)	-	326354..326596 (-)	243	WP_003135050.1	type B 50S ribosomal protein L31	-
VNN36_RS01670 (VNN36_01670)	-	326708..328612 (-)	1905	WP_014024348.1	fructose-specific PTS transporter subunit EIIC	-
VNN36_RS01675 (VNN36_01675)	pfkB	328627..329553 (-)	927	WP_004259111.1	1-phosphofructokinase	-

Sequence

Protein

• Length: 496 a.a.
• Molecular weight: 56771.74 Da
• Isoelectric Point: 5.1990

>NTDB_id=918742 VNN36_RS01650 WP_339013680.1 323210..324700(-) (covS) [Lactococcus garvieae strain R22-8]
MVKFFDSKKKKTESLPERKRSIMLRWAFANTIFCFITFTIFTVLVYQLTITTFINSEKEDMMKALDNVEQSLSQSESTLS
EENLANYLAYAKDYTASSQGKENELETLGSMIGSRKSFYVFDVGENLIYSTNSHGFPLKKDVGDGTHAVRTFGEYSGYLV
ERPVYSNKTGKLIGYVQAFYDMSYYYSVRTKLLIALIILEIIALFIAQFVGYFMASRYIKPLERLHDAITTRANNLKADF
KPVVIQTGDEIEELATVYNDMMIKLNDYVDQQKRFVSDVSHELRTPLAVLDGHLNLLNRWGKNDPEVLEESLQASIEEVS
TMRTMLEEMLALARLENIDFQDEDLICDPTEVSNFLKKNFLLIHADLSLTVENNLSTGRLAHIYPNHYEQGLKILIDNAI
KYSPKDRQEVKIHLEEDDKYIITTVEDHGYGISQEDLKHVFERFFRADKARNRDIGGTGLGLSIIQRIVENYDGEVSVTS
VVGEGSKFTLKIPKIK

Nucleotide

• Length: 1491 bp

>NTDB_id=918742 VNN36_RS01650 WP_339013680.1 323210..324700(-) (covS) [Lactococcus garvieae strain R22-8]
ATGGTAAAATTTTTTGATTCGAAGAAGAAAAAAACAGAAAGTCTTCCCGAGCGTAAGCGAAGCATCATGCTACGTTGGGC
ATTTGCAAATACGATTTTTTGTTTTATTACCTTCACTATTTTTACAGTATTGGTTTACCAATTGACCATTACAACCTTCA
TCAATTCTGAAAAAGAGGATATGATGAAAGCTCTGGATAATGTTGAGCAAAGTTTGTCCCAATCGGAAAGCACACTGTCG
GAAGAAAATCTGGCGAATTATTTGGCTTATGCCAAAGACTATACAGCCTCCAGTCAGGGAAAAGAAAATGAGCTAGAAAC
ACTTGGAAGTATGATTGGCTCTAGGAAGTCTTTTTATGTTTTTGACGTCGGTGAAAATTTGATTTACTCGACCAATTCGC
ATGGCTTCCCTCTAAAAAAAGACGTGGGGGATGGCACTCATGCTGTACGTACATTTGGTGAATATTCTGGTTATTTGGTC
GAACGACCAGTTTATTCTAATAAAACAGGTAAGCTGATTGGCTATGTGCAGGCTTTCTATGATATGAGTTATTATTATAG
CGTCCGAACAAAGTTACTGATTGCCCTGATTATCTTAGAGATTATTGCTCTCTTTATCGCTCAGTTTGTCGGTTATTTTA
TGGCGAGTCGTTACATCAAGCCTCTGGAACGGTTGCACGATGCGATTACTACACGTGCCAATAACTTGAAGGCGGATTTC
AAACCTGTAGTGATTCAAACAGGTGATGAAATTGAAGAACTGGCGACTGTTTATAATGACATGATGATCAAACTTAACGA
TTATGTTGATCAGCAGAAGCGTTTTGTTTCTGATGTCAGTCACGAGTTACGTACGCCACTTGCGGTTTTGGATGGTCATT
TGAATCTCTTGAACCGCTGGGGGAAAAACGATCCCGAGGTGCTTGAGGAGTCTTTACAGGCCAGTATAGAAGAAGTGAGT
ACGATGAGAACAATGTTGGAAGAGATGCTTGCATTGGCCCGTCTTGAAAACATCGATTTTCAAGATGAAGACCTTATCTG
TGATCCGACAGAAGTTTCTAATTTCCTTAAGAAAAACTTCCTACTTATTCATGCTGATTTAAGCTTAACTGTTGAAAATA
ACTTGTCAACGGGAAGATTGGCTCATATCTATCCCAACCATTATGAACAAGGTTTAAAAATTTTGATTGATAATGCGATA
AAATATTCGCCTAAAGATCGCCAAGAAGTGAAAATTCATCTAGAAGAAGATGATAAATACATTATCACTACGGTTGAGGA
TCATGGCTATGGCATTAGTCAGGAAGATTTAAAACATGTCTTTGAGCGTTTCTTCCGTGCTGATAAAGCGCGAAATCGGG
ATATAGGAGGCACTGGGCTTGGACTGTCTATTATCCAACGCATAGTGGAAAACTACGATGGGGAGGTCAGTGTGACTTCT
GTTGTAGGTGAGGGATCGAAATTCACTTTAAAAATTCCTAAGATTAAATAA

Domains

Predicted by InterproScan.

• HAMP domain (HAMP) (214-266)

• His Kinase A (phospho-acceptor) domain (HisKA) (272-337)

• ArlS sensor domain (ArlS_N) (52-190)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (389-494)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
covS	Lactococcus lactis subsp. lactis strain DGCC12653	56.137	100	0.563