Detailed information NTG0918730

Bioinformatically predicted

Overview

• Name: covS
• Type: Regulator
• Locus tag: VNN41_RS09450
• Genome accession: NZ_CP141713
• Coordinates: 1864268..1865758 (+)
• Length: 496 a.a.
• NCBI ID: WP_407350301.1
• Uniprot ID: -
• Organism: Lactococcus garvieae strain VC11
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1859268..1870758

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VNN41_RS09425 (VNN41_09415)	pfkB	1859415..1860341 (+)	927	WP_004259111.1	1-phosphofructokinase	-
VNN41_RS09430 (VNN41_09420)	-	1860356..1862260 (+)	1905	WP_014024348.1	fructose-specific PTS transporter subunit EIIC	-
VNN41_RS09435 (VNN41_09425)	-	1862372..1862614 (+)	243	WP_003135050.1	type B 50S ribosomal protein L31	-
VNN41_RS09440 (VNN41_09430)	-	1862831..1863382 (+)	552	WP_407350300.1	YceD family protein	-
VNN41_RS09445 (VNN41_09435)	covR	1863484..1864179 (+)	696	WP_004259096.1	response regulator transcription factor	Regulator
VNN41_RS09450 (VNN41_09440)	covS	1864268..1865758 (+)	1491	WP_407350301.1	ATP-binding protein	Regulator
VNN41_RS09455 (VNN41_09445)	-	1866155..1867726 (+)	1572	WP_407350302.1	ABC transporter permease subunit	-
VNN41_RS09460 (VNN41_09450)	-	1867727..1868464 (+)	738	WP_014024353.1	amino acid ABC transporter ATP-binding protein	-
VNN41_RS09465 (VNN41_09455)	murD	1868603..1869964 (+)	1362	WP_141921009.1	UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase	-

Sequence

Protein

• Length: 496 a.a.
• Molecular weight: 56753.73 Da
• Isoelectric Point: 5.1966

>NTDB_id=918730 VNN41_RS09450 WP_407350301.1 1864268..1865758(+) (covS) [Lactococcus garvieae strain VC11]
MVKFFDSKKKKTESLPERKRSIMLRWAFANTIFCFITFTIFTVLVYQLTITTFINSEKEDMMKALDNVDQSLSQSESTLS
EENLANYLAYAKDYTASSQGKENELETLGSMIGSRKSFYVFDVGENLIYSTNSHGFPLKKDVGDGTHAVRTFGEYSGYLV
ERPVYSNKTGKLIGYVQAFYDMSYYYSVRTKLLIALIILEIIALFIAQFVGYFMASRYIKPLERLHDAITTRANNLKADF
KPVVIQTGDEIEELATVYNDMMIKLNDYVDQQKRFVSDVSHELRTPLAVLDGHLNLLNRWGKNDPEVLEESLQASIEEVS
TMRTMLEEMLALARLENIDFQDEDLICDPTEVSNFLKKNFLIIHADLSLTVENNLSPGRLAHIYPNHYEQGLKILIDNAI
KYSPKDRQEVKIHLEEDDKYIITTVEDHGYGISQEDLKHVFERFFRADKARNRDIGGTGLGLSIIQRIVENYDGEVSVTS
VVGEGSKFTLKIPKIK

Nucleotide

• Length: 1491 bp

>NTDB_id=918730 VNN41_RS09450 WP_407350301.1 1864268..1865758(+) (covS) [Lactococcus garvieae strain VC11]
ATGGTAAAATTTTTTGATTCGAAGAAGAAAAAAACAGAAAGTCTTCCCGAGCGTAAGCGAAGCATCATGCTCCGTTGGGC
ATTTGCAAATACGATTTTTTGTTTTATTACCTTCACTATTTTTACAGTATTGGTTTATCAATTGACCATTACAACCTTCA
TCAATTCTGAAAAAGAGGATATGATGAAAGCTCTGGATAATGTTGATCAAAGTTTGTCCCAATCGGAAAGCACACTGTCG
GAAGAAAATCTGGCGAATTATTTGGCTTATGCCAAAGACTATACAGCCTCCAGTCAGGGTAAAGAAAATGAGCTAGAAAC
ACTTGGAAGTATGATTGGCTCTAGGAAGTCCTTTTATGTTTTTGACGTCGGTGAAAATTTGATTTACTCGACCAATTCTC
ATGGCTTCCCTCTAAAAAAAGACGTGGGGGATGGCACTCATGCTGTACGTACATTTGGTGAATATTCTGGTTATTTGGTG
GAACGACCGGTTTATTCTAATAAAACAGGTAAGCTGATTGGCTATGTACAGGCTTTCTATGATATGAGTTATTATTATAG
CGTGCGAACAAAGTTACTGATTGCCCTGATTATCTTAGAGATTATTGCTCTCTTTATCGCTCAGTTTGTCGGTTATTTTA
TGGCGAGTCGTTACATCAAGCCTCTGGAACGGTTGCACGATGCGATTACTACACGTGCCAATAACTTGAAGGCGGATTTC
AAACCTGTAGTGATTCAAACAGGTGATGAAATTGAAGAACTGGCGACTGTTTATAATGACATGATGATCAAGCTTAACGA
TTATGTTGATCAGCAGAAGCGTTTTGTTTCTGATGTCAGTCACGAGTTACGTACGCCACTTGCGGTTTTGGATGGTCATT
TGAATCTCTTGAACCGTTGGGGGAAAAATGATCCCGAAGTGCTTGAGGAGTCTTTACAGGCCAGTATAGAAGAAGTGAGT
ACGATGAGAACAATGTTGGAAGAGATGCTTGCATTGGCCCGTCTTGAAAACATCGATTTTCAAGATGAAGACCTTATCTG
TGATCCGACAGAAGTTTCTAATTTCCTTAAGAAAAACTTCCTAATTATTCATGCTGATTTAAGCTTAACTGTGGAAAATA
ACTTGTCACCGGGAAGATTGGCTCATATCTACCCGAACCATTATGAACAAGGCTTAAAAATTTTGATTGATAATGCTATA
AAATATTCGCCTAAAGATCGCCAAGAAGTGAAAATTCATCTAGAAGAAGATGATAAATACATTATCACTACGGTTGAGGA
TCATGGCTATGGCATTAGTCAGGAAGATTTAAAACATGTCTTTGAGCGTTTCTTCCGTGCTGATAAAGCGCGAAATCGGG
ATATAGGAGGCACTGGGCTTGGACTGTCTATTATCCAACGCATAGTGGAAAACTATGATGGGGAGGTCAGTGTGACTTCT
GTTGTAGGTGAGGGATCGAAATTCACTTTAAAAATTCCTAAGATTAAATAA

Domains

Predicted by InterproScan.

• ArlS sensor domain (ArlS_N) (52-190)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (389-494)

• HAMP domain (HAMP) (214-266)

• His Kinase A (phospho-acceptor) domain (HisKA) (272-337)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
covS	Lactococcus lactis subsp. lactis strain DGCC12653	55.734	100	0.558