Detailed information NTG0918589

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: VNN32_RS05905
• Genome accession: NZ_CP141703
• Coordinates: 1116567..1119017 (+)
• Length: 816 a.a.
• NCBI ID: WP_046401078.1
• Uniprot ID: -
• Organism: Lactococcus petauri strain R21-74 AL-1
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1111567..1124017

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VNN32_RS05880 (VNN32_05875)	-	1112488..1113000 (+)	513	WP_003134000.1	adenine phosphoribosyltransferase	-
VNN32_RS05885 (VNN32_05880)	rpoE	1113126..1113686 (+)	561	WP_003134001.1	DNA-directed RNA polymerase subunit delta	-
VNN32_RS05890 (VNN32_05885)	mltG	1113792..1115507 (+)	1716	WP_019335936.1	endolytic transglycosylase MltG	-
VNN32_RS05895 (VNN32_05890)	greA	1115532..1116005 (+)	474	WP_019292667.1	transcription elongation factor GreA	-
VNN32_RS05900 (VNN32_05895)	-	1116125..1116577 (+)	453	WP_019292666.1	CtsR family transcriptional regulator	-
VNN32_RS05905 (VNN32_05900)	clpC	1116567..1119017 (+)	2451	WP_046401078.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
VNN32_RS05910 (VNN32_05905)	raiA	1119140..1119697 (+)	558	WP_003134010.1	ribosome-associated translation inhibitor RaiA	-
VNN32_RS05915 (VNN32_05910)	pflB	1119945..1122278 (+)	2334	WP_019292664.1	formate C-acetyltransferase	-
VNN32_RS05920 (VNN32_05915)	coaE	1122516..1123121 (+)	606	WP_019292663.1	dephospho-CoA kinase	-

Sequence

Protein

• Length: 816 a.a.
• Molecular weight: 91146.43 Da
• Isoelectric Point: 6.0555

>NTDB_id=918589 VNN32_RS05905 WP_046401078.1 1116567..1119017(+) (clpC) [Lactococcus petauri strain R21-74 AL-1]
MKFNEKDFTPQVVKVLEKSADYAHKFNYAWVESSHLLAALAEVPASLAFTLLNSEKIDLEEMLIDIEDFSSQVKTKKSEI
KLSPRVETIIEQARALAQNNDKNRIGTEHLLYMLLANEASFAGQLLREQDINIVNLRKKLEQKAYLRVPERRKAVTPASK
RNLSGKVSETTTTPTLDTVSTDLTKAAREGKLDPMIGREREVERLIHILSRRTKNNPVLVGEPGVGKSAIIEGFATRVAA
GNVPVGLRGSRIMALNMAMVVAGTKFRGEFEDRLTAIVDEVTHDKDVIVFIDELHTIIGAGGGMDSVNDASNILKPALAR
GEFQLIGATTYQEYQKYIEKDEALERRFARVNVEEPSEEETVAILQGLKEKFEAYHIVKFEEGALERAVSLSNRYMPSRR
LPDKAIDLLDEAAAKVKITSKTNYTKLDELKAELKAEELRLQKAVVALDIVEAQGIEKDIEKLTHKIDNFTVSENDNPLV
EESDVYAVVSNLTGIPLQQMTKTESERLINLEKELHKRVVGQEEAISAVSRAIRRARSGIADTRRPLGSFMFLGPTGVGK
TELAKALAESVFGSEENMIRVDMSEFMEKFSTSRLIGAPPGYVGYDEGGQLTEQVRNKPYSVILLDEVEKAHPDIFNIML
QILDDGFVTDTKGRKVDFRNTIIIMTSNLGATAIRDDKTVGFGAKSISTDYPAMKARIMEELKKQYRPEFLNRIDETIVF
HSLTEKEIEQVVKIMSKSLVSRLKDQNIKVKFTPAALKVIADKGFDPEYGARPLRKALQREVEDTLSEQLLAGEIHPGDT
ISIGSSNKKIRISVID

Nucleotide

• Length: 2451 bp

>NTDB_id=918589 VNN32_RS05905 WP_046401078.1 1116567..1119017(+) (clpC) [Lactococcus petauri strain R21-74 AL-1]
ATGAAATTTAATGAAAAGGACTTTACACCACAAGTCGTAAAAGTGCTTGAGAAGTCTGCCGACTATGCGCACAAGTTTAA
CTACGCGTGGGTTGAAAGCTCGCACCTATTGGCTGCCTTGGCTGAGGTCCCGGCTTCATTGGCATTTACGCTACTTAATT
CAGAAAAGATTGATTTGGAAGAAATGTTAATCGACATCGAAGATTTTTCAAGTCAAGTGAAGACAAAAAAATCAGAAATA
AAGCTTAGTCCAAGAGTCGAAACGATTATTGAGCAAGCACGAGCACTAGCTCAAAATAATGATAAAAACCGCATCGGAAC
CGAGCATCTCTTATATATGCTGTTGGCAAATGAAGCCAGCTTTGCAGGACAACTTTTACGTGAGCAAGACATCAATATCG
TTAACCTCCGCAAAAAGCTAGAGCAAAAAGCATATCTACGTGTACCAGAGCGCCGTAAAGCGGTGACACCAGCTTCGAAA
AGAAACCTGTCGGGGAAAGTGTCCGAAACAACGACGACACCTACTTTAGACACGGTATCAACAGATTTGACAAAAGCAGC
CCGTGAAGGCAAGCTTGATCCCATGATTGGAAGAGAGCGTGAAGTTGAACGTCTTATCCACATTTTGAGCCGGCGAACAA
AAAATAATCCCGTTCTTGTTGGTGAGCCAGGTGTTGGTAAGTCAGCGATTATTGAAGGCTTTGCGACACGTGTGGCTGCA
GGAAATGTTCCTGTAGGTTTACGTGGTAGCCGCATTATGGCTTTAAATATGGCGATGGTCGTAGCGGGGACAAAATTCCG
TGGTGAATTTGAAGATCGTTTAACGGCTATTGTTGATGAAGTGACACACGATAAAGATGTTATCGTCTTTATCGATGAAC
TGCATACAATCATTGGGGCTGGTGGCGGCATGGACTCGGTCAACGATGCCTCAAACATTTTAAAACCAGCATTAGCACGG
GGCGAGTTCCAACTCATCGGTGCTACCACTTATCAAGAATATCAAAAATATATTGAAAAAGATGAAGCCCTAGAACGCCG
TTTTGCCCGTGTCAATGTCGAAGAACCCTCAGAAGAGGAAACGGTTGCGATTTTACAAGGTTTGAAAGAAAAATTTGAGG
CTTACCATATAGTCAAATTTGAAGAAGGGGCTTTGGAGCGTGCTGTCAGCTTGAGTAATCGCTATATGCCTAGTCGTCGT
CTCCCAGACAAAGCTATTGATCTTCTTGATGAAGCAGCAGCCAAAGTTAAAATCACGAGTAAAACAAATTATACCAAGTT
AGACGAGTTAAAAGCAGAATTAAAAGCGGAAGAACTGAGATTACAAAAAGCAGTTGTTGCTCTTGATATTGTTGAAGCGC
AAGGGATTGAAAAAGATATTGAAAAATTAACGCACAAGATTGATAATTTTACAGTATCGGAAAATGATAATCCTTTGGTG
GAGGAAAGCGATGTTTATGCTGTCGTTTCTAACCTTACAGGAATCCCACTCCAACAGATGACGAAGACAGAAAGTGAACG
TCTGATTAACTTAGAAAAAGAGTTACATAAACGTGTGGTTGGACAGGAAGAAGCGATTTCTGCTGTTTCTCGTGCCATTA
GACGTGCACGTTCAGGGATTGCCGATACGAGACGTCCTTTGGGCTCATTTATGTTCCTTGGTCCGACAGGAGTTGGGAAG
ACAGAGCTTGCTAAGGCTTTAGCGGAAAGTGTTTTTGGCAGTGAAGAAAATATGATTCGTGTAGACATGAGTGAATTTAT
GGAAAAATTCTCGACATCGCGTCTTATCGGAGCACCTCCTGGATATGTAGGTTACGATGAAGGTGGGCAATTGACAGAGC
AAGTCCGTAATAAGCCTTATTCTGTTATTCTCCTTGATGAAGTCGAAAAGGCCCACCCTGATATTTTCAATATCATGTTA
CAAATTTTGGATGATGGTTTCGTTACAGATACCAAAGGACGTAAAGTTGATTTCAGAAATACGATCATCATTATGACATC
TAACTTGGGTGCAACGGCTATTCGTGATGATAAAACGGTTGGTTTTGGGGCTAAATCAATTTCAACGGATTATCCAGCTA
TGAAAGCAAGAATCATGGAAGAGCTGAAGAAACAGTACCGTCCAGAATTTCTCAATCGTATCGATGAAACTATCGTTTTC
CATTCACTGACAGAAAAAGAGATTGAACAAGTCGTGAAAATCATGAGTAAATCTCTTGTATCGCGTTTGAAAGATCAAAA
TATCAAAGTAAAATTTACACCTGCTGCTTTGAAAGTTATTGCTGATAAAGGATTTGATCCTGAATACGGTGCCCGCCCAT
TGCGTAAAGCTCTGCAACGTGAGGTTGAAGACACGCTCAGTGAACAATTGCTTGCCGGCGAAATTCATCCAGGGGATACG
ATTTCGATTGGTTCTTCTAATAAAAAGATTAGAATAAGTGTTATTGATTGA

Domains

Predicted by InterproScan.

• AAA lid domain (AAA_lid_9) (357-445)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (21-69)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (93-142)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (723-803)

• ATPase family associated with various cellular activities (AAA) (AAA) (218-349)

• AAA domain (Cdc48 subfamily) (AAA_2) (545-716)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	70.92	99.877	0.708
clpC	Streptococcus thermophilus LMG 18311	49.879	100	0.506
clpC	Streptococcus thermophilus LMD-9	49.879	100	0.506
clpC	Streptococcus pneumoniae TIGR4	49.274	100	0.499
clpC	Streptococcus pneumoniae Rx1	49.153	100	0.498
clpC	Streptococcus pneumoniae D39	49.153	100	0.498
clpC	Streptococcus mutans UA159	47.488	100	0.487
clpC	Bacillus subtilis subsp. subtilis str. 168	48.564	98.162	0.477
clpE	Streptococcus mutans UA159	46.719	78.431	0.366