Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   VNN52_RS01350 Genome accession   NZ_CP141701
Coordinates   269692..271182 (-) Length   496 a.a.
NCBI ID   WP_019293246.1    Uniprot ID   A0AAJ2ML94
Organism   Lactococcus petauri strain M18012501 FF2g6     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 264692..276182
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VNN52_RS01335 (VNN52_01335) murD 265486..266847 (-) 1362 WP_019292073.1 UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase -
  VNN52_RS01340 (VNN52_01340) - 266987..267724 (-) 738 WP_019292074.1 amino acid ABC transporter ATP-binding protein -
  VNN52_RS01345 (VNN52_01345) - 267725..269296 (-) 1572 WP_019292075.1 ABC transporter permease subunit -
  VNN52_RS01350 (VNN52_01350) covS 269692..271182 (-) 1491 WP_019293246.1 HAMP domain-containing histidine kinase Regulator
  VNN52_RS01355 (VNN52_01355) covR 271270..271965 (-) 696 WP_019292077.1 response regulator transcription factor Regulator
  VNN52_RS01360 (VNN52_01360) - 272067..272618 (-) 552 WP_153924561.1 DUF177 domain-containing protein -
  VNN52_RS01365 (VNN52_01365) - 272835..273077 (-) 243 WP_003135050.1 type B 50S ribosomal protein L31 -
  VNN52_RS01370 (VNN52_01370) - 273189..275093 (-) 1905 WP_019292079.1 fructose-specific PTS transporter subunit EIIC -
  VNN52_RS01375 (VNN52_01375) pfkB 275108..276034 (-) 927 WP_153924558.1 1-phosphofructokinase -

Sequence

Protein


Download         Length: 496 a.a.        Molecular weight: 56888.98 Da        Isoelectric Point: 5.2995

>NTDB_id=918520 VNN52_RS01350 WP_019293246.1 269692..271182(-) (covS) [Lactococcus petauri strain M18012501 FF2g6]
MVKFFDSKKKKAENLPERKRSIMLRWAFANTIFCFITFTIFTVLVYQLTITTFINSEKEDMMKALDNVEQSLSQSESKLS
EDNLANYLAYAKDYTASSQGKENELETLGSMIGSRKSFYVFDVGENLIYSTNSYGFPLRKDVGDSTHAVRTFGEYSGYLV
ERPVHSKKTGKLIGYVQAFYDMSYYYSVRTKLLIALIILEIIALFIAQFVGYFMASRYIKPLERLHDAITTRANNLKADF
KPVVIQTGDEIEELATVYNDMMIKLNDYVDQQKRFVSDVSHELRTPLAVLDGHLNLLNRWGKNDPEVLEESLQASIEEVS
TMRTMLEEMLALARLESIDFQDEDLICDPTEVSNFLKKNFLLIHPDLNLTVENYLTPGSLAHIYPNHYEQGLKILIDNAI
KYSPKDRQEVKIHLEEDDKYIITTVEDRGYGISQEDLKHVFERFFRADKARNRDIGGTGLGLSIIQRIVENYDGDVSVTS
IVGEGSKFTLKIPKIK

Nucleotide


Download         Length: 1491 bp        

>NTDB_id=918520 VNN52_RS01350 WP_019293246.1 269692..271182(-) (covS) [Lactococcus petauri strain M18012501 FF2g6]
ATGGTAAAATTTTTTGATTCGAAGAAGAAAAAAGCAGAAAATCTGCCCGAGCGTAAGCGAAGCATCATGCTACGTTGGGC
CTTTGCAAATACGATTTTTTGTTTTATAACCTTCACTATTTTTACAGTATTAGTTTATCAACTGACCATAACAACCTTCA
TCAATTCTGAAAAAGAGGACATGATGAAAGCTCTGGACAATGTTGAGCAAAGTTTGTCCCAATCGGAAAGCAAACTGTCG
GAGGACAATCTTGCGAATTATTTGGCTTATGCCAAAGACTACACAGCATCCAGTCAGGGAAAAGAAAATGAGCTAGAAAC
ACTTGGAAGTATGATTGGTTCTAGGAAGTCTTTTTATGTCTTTGATGTCGGTGAAAATTTGATTTATTCGACCAATTCGT
ATGGTTTCCCGCTAAGGAAAGATGTGGGGGATTCTACTCATGCTGTACGTACATTTGGTGAATATTCTGGTTATTTGGTT
GAACGACCCGTTCATTCTAAGAAAACAGGGAAACTGATTGGCTATGTGCAGGCTTTCTATGATATGAGTTATTATTACAG
CGTGCGAACAAAGCTGCTGATTGCCTTGATTATCTTAGAAATTATTGCTCTCTTTATTGCTCAGTTTGTCGGTTATTTTA
TGGCAAGTCGCTATATCAAGCCTCTAGAGCGTTTGCACGATGCGATTACTACACGTGCCAATAATTTGAAGGCGGATTTC
AAACCTGTAGTGATTCAAACAGGCGATGAAATTGAAGAACTGGCGACTGTTTATAACGATATGATGATTAAGCTTAACGA
TTACGTTGATCAGCAGAAACGTTTTGTTTCTGATGTCAGTCACGAGCTACGTACGCCACTTGCAGTTTTAGATGGTCATT
TGAATCTCTTGAATCGATGGGGGAAAAATGATCCTGAAGTGCTTGAGGAGTCTTTACAGGCCAGTATAGAAGAAGTTAGC
ACGATGAGAACGATGTTAGAGGAGATGCTTGCATTGGCCCGTCTTGAAAGCATTGATTTTCAAGATGAAGATCTGATCTG
TGATCCAACAGAAGTTTCTAATTTTCTTAAGAAAAACTTTCTCCTTATTCATCCTGATTTAAATTTAACTGTTGAGAATT
ACTTGACGCCGGGTAGTTTGGCTCATATTTATCCCAACCATTATGAACAAGGCTTAAAAATTTTGATTGATAATGCGATA
AAATACTCGCCTAAAGATCGCCAAGAAGTGAAAATCCATCTAGAAGAAGATGACAAATACATTATTACGACAGTTGAGGA
TCGTGGCTATGGCATTAGTCAAGAAGATTTAAAACATGTCTTTGAGCGCTTTTTCCGTGCCGATAAAGCACGAAATCGAG
ATATAGGTGGAACAGGTCTTGGTCTGTCTATTATCCAACGCATAGTGGAAAACTATGACGGGGATGTCAGTGTGACTTCC
ATTGTAGGCGAAGGATCGAAATTTACTTTAAAAATTCCTAAGATTAAATAA

Domains

Predicted by InterproScan.

HAMP domain (HAMP)

(214-266)

His Kinase A (phospho-acceptor) domain (HisKA)

(272-337)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(389-494)

ArlS sensor domain (ArlS_N)

(52-190)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Lactococcus lactis subsp. lactis strain DGCC12653

55.823

100

0.56