Detailed information NTG0918508

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: VNN27_RS05535
• Genome accession: NZ_CP141700
• Coordinates: 1115876..1118122 (+)
• Length: 748 a.a.
• NCBI ID: WP_061414798.1
• Uniprot ID: -
• Organism: Lactococcus petauri strain R22-25 IC35
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1110876..1123122

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VNN27_RS05520 (VNN27_05520)	dnaG	1112354..1114240 (+)	1887	WP_252169886.1	DNA primase	-
VNN27_RS05525 (VNN27_05525)	-	1114276..1114419 (+)	144	Protein_1033	translation initiation factor IF-2 N-terminal domain-containing protein	-
VNN27_RS05530 (VNN27_05530)	rpoD	1114534..1115658 (+)	1125	WP_306723678.1	RNA polymerase sigma factor RpoD	-
VNN27_RS05535 (VNN27_05535)	clpC	1115876..1118122 (+)	2247	WP_061414798.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
VNN27_RS05540 (VNN27_05540)	-	1118177..1118712 (+)	536	Protein_1036	HD domain-containing protein	-
VNN27_RS05545 (VNN27_05545)	def	1119085..1119711 (-)	627	WP_017370260.1	peptide deformylase	-
VNN27_RS05550 (VNN27_05550)	-	1119816..1120271 (+)	456	WP_017370530.1	RNA pyrophosphohydrolase	-
VNN27_RS05555 (VNN27_05555)	uvrB	1120268..1122256 (+)	1989	WP_019292957.1	excinuclease ABC subunit UvrB	-
VNN27_RS05560 (VNN27_05560)	fabZ	1122283..1122741 (-)	459	WP_003134189.1	3-hydroxyacyl-ACP dehydratase FabZ	-

Sequence

Protein

• Length: 748 a.a.
• Molecular weight: 83401.36 Da
• Isoelectric Point: 4.7218

>NTDB_id=918508 VNN27_RS05535 WP_061414798.1 1115876..1118122(+) (clpC) [Lactococcus petauri strain R22-25 IC35]
MLCQNCKINEATIHLYTNVNGQRKQVDLCQNCYQIMKSGGQESLFAGATNISNNDDPFNPFPDIFQALHGNDQGRTMTPP
TQAGGRGPGGPQNPRGSQAPKGLLEEFGVNITDAARRGEIDPVIGRDSEITRVIEILNRRTKNNPVLIGEPGVGKTAVVE
GLAQKIVDGDVPQKLQNKEVIRLDVVSLVQGTGVRGQFEERMQKLMEEIRKRDDVILFIDEIHEIVGAGSAGEGNMDAGN
ILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVDETITILRGIQKRYEDYHHVKYSDEAILAAANLSN
RYIQDRFLPDKAIDLLDEAGSKKNLTLKFVDPEDIKKRIEQAEAQKNEAMQREDFEKAAHFRDQIAKLRELQSHEISDTD
MPNITEKDIEAIVEEKTHIPVGDLKEKEQTQLINLAEDLKEHVIGQDEAIDKISKAVRRSRVGLGKPNRPIGSFLFVGPT
GVGKTELAKQLAYELFGSRDSMIRFDMSEYMEKHSVAKLIGAPPGYVGYEEAGQLTERVRRNPYSLILLDEIEKAHPDVM
HMFLQILDDGRLTDAQGRTVSFKDAIIIMTSNAGTGKVEASVGFGAAREGRTNSVLGELGNFFSPEFMNRFDAIIEFSAL
SKENLLKIVDLMLDEVNAQIAQNDIHLDVTQAVKEKLVDLGYDPKMGARPLRRTIQDNIEDAIADFYIEHPEYKELLADL
VDDKIVIVNKPEEVKDTADTSDTEDEEK

Nucleotide

• Length: 2247 bp

>NTDB_id=918508 VNN27_RS05535 WP_061414798.1 1115876..1118122(+) (clpC) [Lactococcus petauri strain R22-25 IC35]
ATGCTCTGCCAAAATTGTAAAATAAACGAAGCGACAATTCACCTTTATACAAATGTGAATGGCCAGCGTAAGCAAGTGGA
TTTATGCCAAAACTGTTATCAAATTATGAAATCAGGTGGTCAAGAAAGCTTGTTTGCTGGAGCTACAAATATTTCGAATA
ATGATGATCCTTTTAATCCATTTCCAGATATTTTCCAAGCCTTACATGGTAATGATCAAGGTCGGACAATGACACCTCCA
ACACAAGCGGGTGGTCGAGGTCCAGGAGGTCCACAAAACCCTCGGGGAAGTCAAGCACCTAAAGGACTTCTTGAAGAATT
CGGAGTCAACATTACTGATGCTGCACGTCGTGGAGAAATAGATCCTGTTATTGGACGAGATTCTGAAATTACACGTGTTA
TCGAAATTTTGAATCGTCGAACAAAAAATAATCCTGTTCTTATTGGTGAACCTGGTGTTGGTAAAACAGCAGTTGTTGAA
GGCTTAGCCCAAAAAATAGTTGATGGTGATGTACCACAAAAACTACAAAATAAAGAAGTTATTCGTCTTGATGTTGTCAG
TCTCGTCCAAGGTACTGGTGTGCGTGGGCAATTTGAAGAGCGTATGCAAAAACTGATGGAAGAGATTCGTAAACGTGATG
ATGTTATCCTCTTCATTGATGAAATTCATGAGATTGTGGGCGCAGGCTCTGCTGGGGAAGGAAATATGGATGCTGGAAAT
ATCCTTAAACCGGCTTTAGCGCGTGGAGAACTCCAACTTGTTGGAGCAACAACCCTCAATGAATATCGAATTATTGAAAA
AGATGCAGCGCTTGAGCGCCGGATGCAACCTGTTAAAGTTGATGAACCTTCTGTAGATGAGACTATCACAATCTTACGTG
GTATTCAAAAACGTTATGAAGATTATCATCATGTAAAATACTCAGATGAAGCAATCTTAGCTGCTGCAAATCTGTCTAAC
CGTTATATTCAGGACCGTTTCCTTCCCGATAAAGCAATAGACTTGCTGGACGAAGCGGGTTCGAAAAAGAATCTGACCCT
CAAATTTGTTGATCCTGAGGACATAAAGAAACGTATTGAGCAAGCAGAGGCGCAAAAAAACGAAGCCATGCAACGTGAAG
ATTTTGAGAAAGCAGCTCATTTCCGTGATCAAATCGCTAAGCTTCGTGAGCTTCAAAGCCATGAAATCTCAGATACTGAC
ATGCCAAATATCACAGAAAAAGATATTGAAGCAATTGTTGAAGAAAAGACACATATACCTGTAGGTGATTTGAAAGAAAA
AGAACAAACACAGCTCATTAATCTAGCTGAAGACTTGAAAGAACATGTTATCGGGCAAGATGAAGCGATTGATAAAATTT
CTAAAGCTGTGCGTCGTTCGCGTGTCGGACTTGGAAAGCCTAATCGTCCTATCGGTTCATTCCTCTTTGTTGGACCTACT
GGTGTAGGGAAGACCGAACTTGCAAAACAATTGGCTTATGAGCTTTTTGGCTCAAGAGATAGCATGATTCGCTTTGACAT
GTCGGAATACATGGAAAAACATAGTGTGGCTAAGTTGATTGGTGCTCCTCCAGGATATGTGGGTTATGAAGAAGCAGGTC
AGTTGACAGAACGTGTGCGCCGTAACCCATACAGCTTAATTTTATTGGATGAGATTGAGAAAGCTCACCCGGATGTAATG
CATATGTTCTTGCAAATTCTTGATGACGGGCGTTTGACAGATGCGCAAGGTCGTACAGTTTCCTTCAAAGATGCTATCAT
CATTATGACATCGAATGCTGGTACAGGTAAGGTTGAAGCAAGTGTTGGTTTTGGCGCTGCACGTGAAGGACGTACGAATT
CAGTGCTTGGAGAGTTGGGTAATTTCTTCAGTCCAGAATTCATGAACCGTTTTGATGCTATCATTGAATTCTCAGCATTG
AGCAAAGAAAACTTGCTTAAGATTGTAGATTTAATGTTGGATGAAGTAAATGCTCAAATCGCTCAAAATGATATTCATCT
TGACGTCACACAGGCGGTTAAAGAAAAACTCGTTGATCTGGGCTACGATCCGAAAATGGGAGCACGCCCATTACGTCGTA
CCATCCAGGATAATATCGAGGATGCTATTGCTGATTTTTATATCGAGCATCCTGAGTATAAAGAATTACTTGCAGATTTG
GTTGATGATAAGATTGTTATTGTGAATAAGCCTGAAGAAGTAAAAGACACAGCGGATACATCTGATACTGAAGATGAAGA
GAAATAA

Domains

Predicted by InterproScan.

• ATPase family associated with various cellular activities (AAA) (AAA) (146-259)

• AAA lid domain (AAA_lid_9) (284-383)

• AAA domain (Cdc48 subfamily) (AAA_2) (469-634)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (640-710)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. cremoris KW2	86.497	100	0.865
clpE	Streptococcus mutans UA159	77.543	100	0.785
clpE	Streptococcus pneumoniae TIGR4	77.702	97.727	0.759
clpE	Streptococcus pneumoniae Rx1	77.702	97.727	0.759
clpE	Streptococcus pneumoniae D39	77.702	97.727	0.759
clpE	Streptococcus pneumoniae R6	77.702	97.727	0.759
clpC	Bacillus subtilis subsp. subtilis str. 168	50.514	91.043	0.46
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	47.798	81.952	0.392
clpC	Streptococcus pneumoniae Rx1	46.935	82.888	0.389
clpC	Streptococcus pneumoniae D39	46.935	82.888	0.389
clpC	Streptococcus pneumoniae TIGR4	46.774	82.888	0.388
clpC	Streptococcus mutans UA159	46.602	82.62	0.385
clpC	Streptococcus thermophilus LMD-9	45.645	82.888	0.378
clpC	Streptococcus thermophilus LMG 18311	45.484	82.888	0.377