Detailed information NTG0918480

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: VNN27_RS01740
• Genome accession: NZ_CP141700
• Coordinates: 363484..365934 (-)
• Length: 816 a.a.
• NCBI ID: WP_346350224.1
• Uniprot ID: -
• Organism: Lactococcus petauri strain R22-25 IC35
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 358484..370934

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VNN27_RS01725 (VNN27_01725)	coaE	359380..359985 (-)	606	WP_346350088.1	dephospho-CoA kinase	-
VNN27_RS01730 (VNN27_01730)	pflB	360223..362556 (-)	2334	WP_019292664.1	formate C-acetyltransferase	-
VNN27_RS01735 (VNN27_01735)	raiA	362804..363361 (-)	558	WP_003134010.1	ribosome-associated translation inhibitor RaiA	-
VNN27_RS01740 (VNN27_01740)	clpC	363484..365934 (-)	2451	WP_346350224.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
VNN27_RS01745 (VNN27_01745)	-	365924..366376 (-)	453	WP_019292666.1	CtsR family transcriptional regulator	-
VNN27_RS01750 (VNN27_01750)	greA	366496..366969 (-)	474	WP_019292667.1	transcription elongation factor GreA	-
VNN27_RS01755 (VNN27_01755)	mltG	366994..368709 (-)	1716	WP_019294152.1	endolytic transglycosylase MltG	-
VNN27_RS01760 (VNN27_01760)	rpoE	368815..369375 (-)	561	WP_003134001.1	DNA-directed RNA polymerase subunit delta	-
VNN27_RS01765 (VNN27_01765)	-	369501..370013 (-)	513	WP_003134000.1	adenine phosphoribosyltransferase	-

Sequence

Protein

• Length: 816 a.a.
• Molecular weight: 91123.35 Da
• Isoelectric Point: 5.9349

>NTDB_id=918480 VNN27_RS01740 WP_346350224.1 363484..365934(-) (clpC) [Lactococcus petauri strain R22-25 IC35]
MKFNEKDFTPQVVKVLEKSVDYAHKFNYAWVESSHLLAALAEVPASLAFTLLNSEKIDLEEMLIDIEDFSSQVKTKKSEI
KLSPRVETIIEQARALAQNNDKNRIGTEHLLYMLLANEASFAGQLLREQDINIVNLRKKLEQKAYLRVPERRKAVTPASK
RNLSGKVSETTTTPTLDTVSTDLTKAAREGKLDPMIGREREVERLIHILSRRTKNNPVLVGEPGVGKSAIIEGFATRVAA
GDVPVGLRGSRIMALNMAMVVAGTKFRGEFEDRLTAIVDEVTHDKDVIVFIDELHTIIGAGGGMDSVNDASNILKPALAR
GEFQLIGATTYQEYQKYIEKDEALERRFARVNVEEPSEDETVAILQGLKEKFEAYHAVKFEEGTLERAVSLSNRYMPSRR
LPDKAIDLLDEAAAKVKITSKTNYTKLDELKAELKAEELRLQKAVVALDIVEAQGIEKDIEKLTHKIDNFTVSENDNPLV
EESDVYAVVSNLTGIPLQQMTKTESERLINLEKELHKRVVGQEEAISAVSRAIRRARSGIADTRRPLGSFMFLGPTGVGK
TELAKALAESVFGSEENMIRVDMSEFMEKFSTSRLIGAPPGYVGYDEGGQLTEQVRNKPYSVILLDEVEKAHPDIFNIML
QILDDGFVTDTKGRKVDFRNTIIIMTSNLGATAIRDDKTVGFGAKSISTDYAAMKARIMEELKKQYRPEFLNRIDETIVF
HSLTEKEIEQVVKIMSKSLVSRLKDQNIKVKFTPAALKVIADKGFDPEYGARPLRKALQREVEDTLSEQLLAGEIHPGDT
ISIGSSNKKIRISVID

Nucleotide

• Length: 2451 bp

>NTDB_id=918480 VNN27_RS01740 WP_346350224.1 363484..365934(-) (clpC) [Lactococcus petauri strain R22-25 IC35]
ATGAAATTTAATGAAAAGGACTTTACACCACAAGTCGTAAAAGTGCTTGAGAAGTCTGTCGACTATGCGCACAAGTTTAA
CTACGCGTGGGTTGAAAGCTCGCACCTATTGGCTGCCTTGGCTGAGGTCCCGGCTTCATTGGCATTTACGCTACTTAATT
CAGAAAAGATTGATTTGGAAGAAATGTTAATCGACATCGAAGATTTTTCAAGTCAAGTGAAGACAAAAAAATCAGAAATA
AAGCTTAGTCCAAGAGTCGAAACGATTATTGAGCAAGCACGAGCACTAGCTCAAAATAATGATAAAAACCGCATCGGAAC
CGAGCATCTCTTATATATGCTGTTGGCAAATGAAGCCAGCTTTGCAGGACAACTTTTACGTGAGCAAGACATCAATATCG
TTAACCTCCGCAAAAAGCTAGAGCAAAAAGCATATCTACGTGTACCAGAGCGCCGTAAAGCGGTGACACCAGCTTCGAAA
AGAAACCTGTCGGGGAAAGTGTCCGAAACAACGACAACGCCTACTTTAGACACGGTATCGACAGATTTGACAAAAGCAGC
CCGTGAAGGCAAGCTTGATCCCATGATTGGAAGAGAGCGAGAAGTCGAACGCCTCATCCACATTTTGAGTCGTCGGACAA
AGAATAATCCTGTTCTTGTTGGTGAACCTGGTGTTGGTAAGTCAGCGATTATTGAAGGCTTTGCGACGCGTGTGGCTGCA
GGGGATGTTCCTGTAGGTTTACGTGGCAGTCGTATCATGGCCTTGAATATGGCGATGGTTGTTGCGGGGACAAAATTCCG
TGGTGAATTTGAAGATCGTTTGACAGCTATCGTTGATGAAGTGACACATGATAAAGATGTGATCGTCTTTATCGATGAAC
TTCATACCATTATCGGTGCTGGTGGAGGTATGGATTCTGTTAATGATGCTTCCAATATCTTAAAACCTGCATTGGCACGT
GGTGAGTTTCAACTTATTGGGGCAACAACTTATCAAGAATATCAAAAATATATTGAAAAAGATGAGGCCCTAGAACGTCG
TTTTGCCCGTGTTAATGTTGAAGAACCATCAGAAGATGAAACAGTTGCAATCTTACAAGGGTTAAAAGAAAAATTTGAAG
CTTACCATGCGGTCAAATTTGAAGAGGGAACTTTGGAACGTGCCGTCAGTCTGAGCAATCGTTATATGCCAAGTCGTCGT
CTGCCGGATAAAGCAATTGATCTCCTTGATGAAGCCGCAGCCAAAGTTAAAATTACGAGTAAAACAAATTACACCAAGCT
TGACGAATTAAAAGCAGAGTTAAAAGCAGAAGAGCTGAGATTACAAAAAGCAGTTGTAGCACTTGATATTGTTGAAGCAC
AGGGGATTGAAAAAGATATTGAAAAGTTAACGCATAAAATTGATAACTTTACAGTATCGGAAAATGATAATCCTTTGGTT
GAGGAAAGCGATGTTTATGCTGTCGTTTCCAACCTTACAGGAATCCCGCTCCAACAGATGACGAAAACAGAAAGTGAACG
TCTGATTAATCTAGAAAAAGAGCTACATAAGCGTGTAGTTGGTCAGGAAGAAGCGATATCGGCTGTTTCTCGTGCCATAA
GACGTGCACGATCAGGTATCGCCGATACGAGACGTCCTTTGGGTTCATTTATGTTCCTTGGTCCGACAGGGGTTGGGAAG
ACAGAGCTTGCTAAGGCTTTAGCGGAAAGTGTTTTTGGCAGTGAAGAAAACATGATTCGCGTAGACATGAGTGAATTTAT
GGAAAAATTCTCGACATCTCGCCTGATCGGAGCGCCTCCAGGCTACGTAGGTTATGATGAAGGGGGACAACTAACAGAGC
AAGTCCGTAATAAGCCTTATTCTGTTATCCTTCTTGATGAAGTCGAAAAGGCCCATCCTGATATTTTCAATATTATGTTA
CAAATTCTAGATGATGGTTTCGTTACAGACACGAAGGGTCGTAAAGTTGATTTCAGAAATACGATTATCATTATGACATC
TAACCTTGGTGCAACAGCTATTCGTGATGATAAAACAGTTGGTTTCGGTGCCAAATCAATCTCAACAGACTATGCAGCTA
TGAAAGCGAGAATCATGGAAGAGCTGAAGAAACAGTACCGTCCAGAATTTCTCAATCGTATCGATGAAACTATCGTTTTC
CATTCACTGACAGAAAAAGAGATTGAACAAGTCGTGAAAATTATGAGTAAATCTCTCGTATCACGCTTGAAAGATCAAAA
TATCAAAGTGAAATTTACACCTGCTGCTTTGAAAGTTATTGCTGATAAAGGATTTGATCCTGAATACGGCGCCCGCCCAT
TGCGTAAAGCTCTGCAACGTGAGGTTGAAGACACGCTCAGTGAGCAATTGCTTGCCGGCGAAATTCATCCGGGGGATACG
ATTTCTATTGGTTCTTCTAATAAAAAGATTAGAATAAGTGTTATTGATTGA

Domains

Predicted by InterproScan.

• AAA lid domain (AAA_lid_9) (357-445)

• AAA domain (Cdc48 subfamily) (AAA_2) (545-716)

• ATPase family associated with various cellular activities (AAA) (AAA) (218-349)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (22-69)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (93-142)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (723-803)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	70.92	99.877	0.708
clpC	Streptococcus thermophilus LMG 18311	49.758	100	0.505
clpC	Streptococcus thermophilus LMD-9	49.758	100	0.505
clpC	Streptococcus pneumoniae TIGR4	49.274	100	0.499
clpC	Streptococcus pneumoniae Rx1	49.153	100	0.498
clpC	Streptococcus pneumoniae D39	49.153	100	0.498
clpC	Streptococcus mutans UA159	47.249	100	0.484
clpC	Bacillus subtilis subsp. subtilis str. 168	48.564	98.162	0.477
clpE	Streptococcus mutans UA159	46.719	78.431	0.366