Detailed information NTG0916692

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: U2H22_RS18170
• Genome accession: NZ_CP141265
• Coordinates: 3588885..3590048 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain L2D39
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3583885..3595048

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
U2H22_RS18140 (U2H22_18140)	-	3584149..3584568 (-)	420	WP_012118571.1	TIGR03826 family flagellar region protein	-
U2H22_RS18145 (U2H22_18145)	comFC	3584642..3585331 (-)	690	WP_199022660.1	phosphoribosyltransferase family protein	Machinery gene
U2H22_RS18150 (U2H22_18150)	-	3585337..3585621 (-)	285	WP_007407481.1	competence protein ComFB	-
U2H22_RS18155 (U2H22_18155)	comFA	3585679..3587064 (-)	1386	WP_124692700.1	DEAD/DEAH box helicase	Machinery gene
U2H22_RS18160 (U2H22_18160)	-	3587173..3588021 (-)	849	WP_003151387.1	DegV family protein	-
U2H22_RS18165 (U2H22_18165)	degU	3588119..3588808 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
U2H22_RS18170 (U2H22_18170)	degS	3588885..3590048 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
U2H22_RS18175 (U2H22_18175)	-	3590271..3590918 (+)	648	WP_007614107.1	YigZ family protein	-
U2H22_RS18180 (U2H22_18180)	-	3590923..3592143 (+)	1221	WP_007407486.1	LCP family protein	-
U2H22_RS18185 (U2H22_18185)	-	3592242..3593318 (-)	1077	WP_003151382.1	MraY family glycosyltransferase	-
U2H22_RS18190 (U2H22_18190)	-	3593451..3594647 (-)	1197	WP_218791395.1	glycosyltransferase	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=916692 U2H22_RS18170 WP_007407484.1 3588885..3590048(-) (degS) [Bacillus velezensis strain L2D39]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=916692 U2H22_RS18170 WP_007407484.1 3588885..3590048(-) (degS) [Bacillus velezensis strain L2D39]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTGCGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGTATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAACGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951