Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   U2H22_RS16065 Genome accession   NZ_CP141265
Coordinates   3182709..3183353 (-) Length   214 a.a.
NCBI ID   WP_003152052.1    Uniprot ID   A3KLB8
Organism   Bacillus velezensis strain L2D39     
Function   promoting transcription of comS (predicted from homology)   
Competence regulation

Genomic Context

Location: 3177709..3188353
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U2H22_RS16030 (U2H22_16030) - 3178888..3179319 (+) 432 WP_007408670.1 Na(+)/H(+) antiporter subunit B -
  U2H22_RS16035 (U2H22_16035) - 3179319..3179660 (+) 342 WP_003152063.1 Na(+)/H(+) antiporter subunit C -
  U2H22_RS16040 (U2H22_16040) - 3179653..3181140 (+) 1488 WP_072589517.1 Na+/H+ antiporter subunit D -
  U2H22_RS16045 (U2H22_16045) - 3181146..3181622 (+) 477 WP_218791341.1 Na+/H+ antiporter subunit E -
  U2H22_RS16050 (U2H22_16050) - 3181622..3181906 (+) 285 WP_012118311.1 Na(+)/H(+) antiporter subunit F1 -
  U2H22_RS16055 (U2H22_16055) mnhG 3181890..3182264 (+) 375 WP_003152056.1 monovalent cation/H(+) antiporter subunit G -
  U2H22_RS16060 (U2H22_16060) - 3182304..3182687 (-) 384 WP_012118312.1 hotdog fold thioesterase -
  U2H22_RS16065 (U2H22_16065) comA 3182709..3183353 (-) 645 WP_003152052.1 response regulator transcription factor Regulator
  U2H22_RS16070 (U2H22_16070) comP 3183434..3185740 (-) 2307 WP_015240483.1 sensor histidine kinase Regulator
  U2H22_RS16075 (U2H22_16075) comX 3185759..3185935 (-) 177 WP_015240484.1 competence pheromone ComX -
  U2H22_RS16080 (U2H22_16080) - 3185950..3186825 (-) 876 WP_025285191.1 polyprenyl synthetase family protein -
  U2H22_RS16085 (U2H22_16085) degQ 3186977..3187117 (-) 141 WP_003152043.1 degradation enzyme regulation protein DegQ Regulator
  U2H22_RS16090 (U2H22_16090) - 3187582..3187923 (+) 342 WP_124692757.1 hypothetical protein -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24271.68 Da        Isoelectric Point: 4.9953

>NTDB_id=916684 U2H22_RS16065 WP_003152052.1 3182709..3183353(-) (comA) [Bacillus velezensis strain L2D39]
MKKILVIDDHPAVMEGTKTILETDTNLSVDCLSPDASEQFVLRHDFSAYDLILMDLNLGDDISGIELSKKILKENPLCKI
IVYTGYEVEDYFEESIRAGLHGAISKTESKEKIMQYIYHVLNGQILVDFSYFKQLMTQQKTKTSSSPQSEQDRLTPRERH
ILQEVEKGLTNQEIADALHLSKRSIEYSLTSIFNKLNVGSRTEAVLIAKSDNVL

Nucleotide


Download         Length: 645 bp        

>NTDB_id=916684 U2H22_RS16065 WP_003152052.1 3182709..3183353(-) (comA) [Bacillus velezensis strain L2D39]
ATGAAAAAGATACTAGTGATTGATGATCATCCGGCTGTCATGGAGGGCACCAAGACGATTCTGGAAACGGACACGAATCT
TTCTGTCGATTGCCTCAGTCCTGATGCCAGTGAACAATTCGTTCTCCGGCATGATTTTTCAGCTTACGATCTCATATTAA
TGGATTTAAATCTGGGTGATGACATCAGCGGCATAGAGCTTTCCAAGAAAATCTTAAAAGAGAATCCTCTCTGTAAAATC
ATTGTCTACACAGGCTATGAGGTTGAAGATTATTTTGAAGAATCCATCCGCGCGGGCCTGCATGGCGCCATCAGCAAAAC
CGAATCTAAAGAGAAAATCATGCAATACATATATCACGTGCTCAACGGACAGATTTTAGTTGATTTCTCCTATTTCAAAC
AGCTGATGACCCAGCAAAAAACAAAAACGTCTTCTTCCCCTCAAAGTGAGCAGGATCGGTTAACCCCGAGAGAGCGACAT
ATTCTCCAAGAGGTCGAAAAAGGTTTGACCAATCAGGAAATCGCAGATGCGCTTCACTTAAGCAAGCGGTCAATTGAATA
CAGCCTGACATCCATTTTTAACAAGCTGAATGTCGGCTCCCGAACTGAAGCGGTGCTGATCGCCAAGTCAGATAACGTAC
TATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-117)

Bacterial regulatory proteins, luxR family (GerE)

(153-208)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A3KLB8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Bacillus subtilis subsp. subtilis str. 168

86.449

100

0.864