Detailed information NTG0916279

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: U2H13_RS17400
• Genome accession: NZ_CP141181
• Coordinates: 3539529..3540692 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus sp. A1
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3534529..3545692

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
U2H13_RS17370 (U2H13_17340)	-	3534794..3535213 (-)	420	WP_014419009.1	TIGR03826 family flagellar region protein	-
U2H13_RS17375 (U2H13_17345)	comFC	3535287..3535976 (-)	690	WP_199449054.1	ComF family protein	Machinery gene
U2H13_RS17380 (U2H13_17350)	-	3535982..3536266 (-)	285	WP_003151389.1	late competence development ComFB family protein	-
U2H13_RS17385 (U2H13_17355)	comFA	3536324..3537709 (-)	1386	WP_029972824.1	DEAD/DEAH box helicase	Machinery gene
U2H13_RS17390 (U2H13_17360)	-	3537817..3538665 (-)	849	WP_003151387.1	DegV family protein	-
U2H13_RS17395 (U2H13_17365)	degU	3538763..3539452 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
U2H13_RS17400 (U2H13_17370)	degS	3539529..3540692 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
U2H13_RS17405 (U2H13_17375)	-	3540915..3541562 (+)	648	WP_007614107.1	YigZ family protein	-
U2H13_RS17410 (U2H13_17380)	-	3541567..3542781 (+)	1215	WP_103526592.1	LCP family protein	-
U2H13_RS17415 (U2H13_17385)	-	3542880..3543956 (-)	1077	WP_003151382.1	glycosyltransferase family 4 protein	-
U2H13_RS17420 (U2H13_17390)	-	3544089..3545285 (-)	1197	WP_060673980.1	glycosyltransferase	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=916279 U2H13_RS17400 WP_007407484.1 3539529..3540692(-) (degS) [Bacillus sp. A1]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=916279 U2H13_RS17400 WP_007407484.1 3539529..3540692(-) (degS) [Bacillus sp. A1]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGTAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTCGAAGAACTCAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTAGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCGTTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTGGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTGCGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTTATCATTAAGGACAACGGAAAAGGTTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951