Detailed information NTG0916259

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: U2H13_RS12605
• Genome accession: NZ_CP141181
• Coordinates: 2587945..2590296 (-)
• Length: 783 a.a.
• NCBI ID: WP_376700479.1
• Uniprot ID: -
• Organism: Bacillus sp. A1
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2582945..2595296

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
U2H13_RS12570 (U2H13_12555)	-	2583311..2583649 (-)	339	WP_007408270.1	YqxA family protein	-
U2H13_RS12575 (U2H13_12560)	spoIIP	2583666..2584859 (-)	1194	WP_222884996.1	stage II sporulation protein P	-
U2H13_RS12580 (U2H13_12565)	gpr	2584927..2586033 (-)	1107	WP_014418417.1	GPR endopeptidase	-
U2H13_RS12585 (U2H13_12570)	rpsT	2586236..2586502 (+)	267	WP_003152876.1	30S ribosomal protein S20	-
U2H13_RS12590 (U2H13_12575)	holA	2586465..2587560 (-)	1096	Protein_2433	DNA polymerase III subunit delta	-
U2H13_RS12595 (U2H13_12580)	-	2587600..2587751 (-)	152	Protein_2434	hypothetical protein	-
U2H13_RS12600 (U2H13_12585)	-	2587792..2587926 (+)	135	WP_003152870.1	YqzM family protein	-
U2H13_RS12605 (U2H13_12590)	comEC	2587945..2590296 (-)	2352	WP_376700479.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
U2H13_RS12610 (U2H13_12595)	-	2590297..2590866 (-)	570	WP_003152868.1	ComE operon protein 2	-
U2H13_RS12615 (U2H13_12600)	comEA	2590933..2591547 (-)	615	WP_376700480.1	helix-hairpin-helix domain-containing protein	Machinery gene
U2H13_RS12620 (U2H13_12605)	comER	2591606..2592427 (+)	822	WP_015240246.1	late competence protein ComER	-
U2H13_RS12625 (U2H13_12610)	-	2592496..2593233 (-)	738	WP_167408922.1	class I SAM-dependent methyltransferase	-
U2H13_RS12630 (U2H13_12615)	rsfS	2593230..2593586 (-)	357	WP_003152864.1	ribosome silencing factor	-
U2H13_RS12635 (U2H13_12620)	yqeK	2593583..2594164 (-)	582	WP_376700481.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
U2H13_RS12640 (U2H13_12625)	-	2594154..2594723 (-)	570	WP_007408258.1	nicotinate-nucleotide adenylyltransferase	-
U2H13_RS12645 (U2H13_12630)	yhbY	2594734..2595024 (-)	291	WP_003152858.1	ribosome assembly RNA-binding protein YhbY	-

Sequence

Protein

• Length: 783 a.a.
• Molecular weight: 86681.70 Da
• Isoelectric Point: 9.1015

>NTDB_id=916259 U2H13_RS12605 WP_376700479.1 2587945..2590296(-) (comEC) [Bacillus sp. A1]
MKYKYLLLPLAAVSATAGIAAAHVFWVLLLFLLYLLFIMIKTKQPAPVIICLVSFCVYFFLYTVCDAANVTRYQAGSYTE
QAVITNIPKVDGAKMSAVIRTHDKEKWAASYKIRSLEEKRLIEQLEPGMRCTFTGSLEQPAHATIPGGFDYKEYLYSQQI
HWLFSVTSIQRCEKSKQPLFKLLNIRKNLISIIRNHVPESSAGIVEALTLGERFSIEDDILSAYQNLGVVHLMAISGMHV
GLITAGLFYALIRIGLTREKAGMLLLLFLPVYTLLSGAAPSVLRASLMLGFYIAGTLVKRGIHSSAALSLSYLLLLLFNP
YLLWQAGFQLSFAVSASLILSSSILKKAGKSRLAGLAMASFIAELSSLPFLLYHFQQISLVSFPMNMVMVPFYTLFVIPV
SVIGFLLLLLSRQVGECLFDMFDLVMKPVHDFITYAASVDLFTMIVSKPDFLSLLLLAVSVFTLFAALEKGGFLKLRKSA
LFFCAVLAYLICRPYFSPWGEADMLDIGQGDSLFISAPHRKGTVMVDTGGVIAYPGESWKEKRHPYSIGEKVLIPFLNGK
GVKKLDALILTHADQDHIGEAGVLIKNHRVKRLIVPVGFVKEPKDQNILKMAKENNIPVAEAKRGDTITAGDLQFQVLSP
ESSDGKSKNDSSLVLWTVLGGVSWLLTGDLESDGETEVLKTYPKLKADILKAGHHGSKSSTSEAFLKQLQPEAALISAGK
ENRYHHPHEEVLDRLKAYSVNVLRTDISGTIQYRFEKGAGTFSVFPPYDIEETRAQEVKKTAD

Nucleotide

• Length: 2352 bp

>NTDB_id=916259 U2H13_RS12605 WP_376700479.1 2587945..2590296(-) (comEC) [Bacillus sp. A1]
ATGAAATATAAATACCTTCTTCTGCCTCTGGCGGCGGTTTCTGCAACTGCGGGGATTGCCGCCGCTCATGTCTTCTGGGT
TCTGCTCCTTTTTCTTCTGTATCTTCTCTTTATTATGATAAAAACAAAGCAGCCTGCCCCGGTTATCATCTGCCTCGTTT
CTTTTTGTGTTTATTTCTTTCTTTATACGGTTTGTGACGCTGCGAATGTAACGCGATATCAGGCCGGCAGTTATACTGAA
CAGGCCGTCATCACTAATATTCCGAAGGTTGACGGAGCGAAAATGTCAGCCGTTATCCGTACACATGACAAGGAAAAATG
GGCGGCTTCGTATAAAATCCGGTCTCTTGAGGAAAAGAGACTCATTGAACAGCTTGAACCGGGGATGCGCTGCACGTTTA
CAGGATCTCTGGAACAGCCTGCACATGCGACGATTCCCGGAGGTTTTGATTATAAGGAATATCTTTACTCTCAGCAGATT
CACTGGTTATTTTCCGTGACTTCCATTCAGCGGTGTGAAAAATCCAAACAGCCGCTGTTTAAACTGCTGAACATCAGAAA
AAATTTGATTTCAATCATTCGGAATCACGTGCCTGAATCTTCCGCCGGAATTGTTGAAGCGCTGACCTTAGGTGAAAGAT
TTTCTATAGAGGACGATATACTGAGTGCATATCAAAATTTGGGAGTCGTTCATTTAATGGCGATTTCCGGAATGCATGTC
GGTCTTATTACGGCGGGACTATTTTATGCTTTGATCAGAATCGGGCTGACAAGAGAAAAGGCGGGGATGTTGCTGCTGCT
GTTTTTGCCGGTATATACGCTGCTGAGCGGTGCCGCCCCATCCGTATTGCGCGCATCCCTCATGCTGGGATTTTATATCG
CCGGAACTCTTGTTAAACGCGGCATTCATTCCTCTGCTGCATTGTCTCTGTCTTATCTGCTGCTCCTGCTGTTTAATCCT
TACCTCCTTTGGCAGGCGGGCTTCCAGCTTTCCTTTGCGGTAAGCGCCTCTTTAATTCTGTCATCCTCCATTTTAAAGAA
AGCAGGGAAAAGCAGACTTGCCGGGCTTGCGATGGCCTCATTCATTGCAGAGCTCAGCTCACTTCCGTTTCTTCTCTATC
ATTTTCAGCAAATTTCACTTGTCAGTTTTCCGATGAACATGGTGATGGTGCCATTTTATACGTTATTTGTCATTCCGGTT
TCTGTCATCGGTTTCCTTCTTCTTTTGCTTTCAAGGCAGGTGGGAGAATGTTTGTTTGATATGTTTGACCTTGTGATGAA
GCCTGTGCATGATTTCATTACATATGCGGCATCCGTTGATTTATTTACTATGATTGTGTCAAAGCCTGACTTTCTTTCCC
TTCTTCTGCTTGCGGTTTCCGTTTTTACGCTTTTTGCGGCTTTGGAAAAGGGAGGTTTTTTAAAACTCAGGAAATCGGCT
CTTTTTTTCTGCGCGGTTTTGGCTTATTTAATATGCCGTCCGTATTTCAGTCCATGGGGAGAAGCGGATATGCTTGATAT
CGGGCAGGGAGACTCGCTGTTTATAAGCGCGCCGCACCGCAAAGGGACCGTAATGGTTGATACAGGGGGAGTGATTGCTT
ATCCCGGAGAATCATGGAAAGAAAAACGCCACCCGTATTCTATCGGCGAGAAGGTTTTGATTCCGTTTTTAAACGGAAAA
GGGGTGAAAAAGCTGGATGCGCTGATTTTAACCCATGCGGATCAGGATCACATCGGAGAAGCCGGAGTGTTAATCAAAAA
TCATAGAGTCAAACGGTTAATTGTCCCCGTGGGATTCGTAAAAGAACCGAAGGATCAGAACATATTAAAAATGGCGAAAG
AAAACAACATTCCCGTTGCCGAAGCAAAACGGGGCGACACCATTACAGCGGGTGATCTTCAGTTTCAGGTGCTGTCTCCG
GAGTCATCTGACGGAAAGAGTAAAAATGATTCGTCACTGGTGCTTTGGACGGTTTTAGGCGGAGTGAGCTGGCTTTTGAC
GGGAGATTTAGAATCGGACGGCGAAACAGAAGTGCTGAAAACGTATCCGAAACTGAAGGCTGATATATTGAAGGCGGGTC
ATCACGGCAGCAAAAGCTCAACGAGTGAAGCCTTTTTGAAACAGCTTCAGCCGGAAGCAGCGCTGATTTCAGCAGGAAAA
GAGAATCGATACCATCATCCGCATGAAGAAGTGCTGGATCGTTTGAAGGCGTACTCTGTCAATGTGCTTCGCACCGATAT
CAGCGGAACGATTCAATACAGATTTGAAAAAGGCGCCGGAACGTTTTCCGTCTTCCCTCCATATGATATAGAAGAAACCA
GGGCGCAAGAAGTAAAAAAGACTGCCGATTGA

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (508-719)

• Domain of unknown function (DUF4131) (DUF4131) (25-170)

• Competence protein (Competence) (208-469)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Bacillus subtilis subsp. subtilis str. 168	56.477	98.595	0.557