Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   U2H13_RS06030 Genome accession   NZ_CP141181
Coordinates   1169861..1170517 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus sp. A1     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1164861..1175517
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U2H13_RS06005 (U2H13_05990) oppF 1165391..1166308 (+) 918 WP_017417453.1 oligopeptide ABC transporter ATP-binding protein OppF -
  U2H13_RS06010 (U2H13_05995) - 1166415..1167602 (+) 1188 WP_376700733.1 putative glycoside hydrolase -
  U2H13_RS06015 (U2H13_06000) - 1167720..1168298 (+) 579 WP_007409110.1 GNAT family N-acetyltransferase -
  U2H13_RS06020 (U2H13_06005) spx 1168477..1168872 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  U2H13_RS06025 (U2H13_06010) - 1168929..1169585 (-) 657 WP_014417421.1 TerC family protein -
  U2H13_RS06030 (U2H13_06015) mecA 1169861..1170517 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  U2H13_RS06035 (U2H13_06020) - 1170669..1171829 (+) 1161 WP_376700734.1 competence protein CoiA family protein -
  U2H13_RS06040 (U2H13_06025) pepF 1172057..1173886 (+) 1830 WP_094296111.1 oligoendopeptidase F Regulator
  U2H13_RS06045 (U2H13_06030) - 1173924..1174091 (-) 168 WP_003155026.1 hypothetical protein -
  U2H13_RS06050 (U2H13_06035) spxH 1174377..1175279 (-) 903 WP_003155024.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=916235 U2H13_RS06030 WP_003155032.1 1169861..1170517(+) (mecA) [Bacillus sp. A1]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=916235 U2H13_RS06030 WP_003155032.1 1169861..1170517(+) (mecA) [Bacillus sp. A1]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAAGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895