Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   U5U21_RS25580 Genome accession   NZ_CP140722
Coordinates   4600019..4600702 (-) Length   227 a.a.
NCBI ID   WP_000350710.1    Uniprot ID   Q81TR3
Organism   Bacillus anthracis strain MH-VW     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 4595019..4605702
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U5U21_RS25565 (U5U21_25635) pepF 4595199..4597025 (-) 1827 WP_000003398.1 oligoendopeptidase F Regulator
  U5U21_RS25570 (U5U21_25640) - 4597076..4598320 (-) 1245 WP_000612267.1 competence protein CoiA -
  U5U21_RS25575 (U5U21_25645) - 4598402..4599946 (-) 1545 WP_000799204.1 cardiolipin synthase -
  U5U21_RS25580 (U5U21_25650) mecA 4600019..4600702 (-) 684 WP_000350710.1 adaptor protein MecA Regulator
  U5U21_RS25585 (U5U21_25655) - 4601029..4601703 (+) 675 WP_000362609.1 TerC family protein -
  U5U21_RS25590 (U5U21_25660) spx 4601753..4602148 (-) 396 WP_000258267.1 transcriptional regulator Spx -
  U5U21_RS25595 (U5U21_25665) - 4602720..4602923 (+) 204 WP_000559980.1 hypothetical protein -
  U5U21_RS25600 (U5U21_25670) - 4602950..4604596 (-) 1647 WP_000727259.1 peptide ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 227 a.a.        Molecular weight: 26966.00 Da        Isoelectric Point: 3.9822

>NTDB_id=915178 U5U21_RS25580 WP_000350710.1 4600019..4600702(-) (mecA) [Bacillus anthracis strain MH-VW]
MDIERINDHTMKFFITYIDIEDRGFNREEIWYDRERSEELFWEMMDEARDHDDFFIDGPLWIQVQAVDKGIEVLVTKAEL
SKDGQKLELPIGVDKIIDIPLDEGIESLFQQELVEEVEEQAGTNFNEDGTFGFLIKFNDFEDVISLSHRLIFEDIKDELY
SFEDRYYVYVEFDEVLHDEEEIDRILSIVLEYGEESTLTIHRVSEYGKQIVKEHALETIRNNFPAKT

Nucleotide


Download         Length: 684 bp        

>NTDB_id=915178 U5U21_RS25580 WP_000350710.1 4600019..4600702(-) (mecA) [Bacillus anthracis strain MH-VW]
TTGGATATTGAAAGAATTAATGATCATACGATGAAGTTTTTTATTACGTACATTGATATAGAGGACAGAGGCTTTAATCG
TGAGGAAATTTGGTATGACCGCGAAAGAAGCGAAGAGCTCTTTTGGGAAATGATGGACGAAGCTCGTGATCATGACGATT
TCTTTATTGATGGGCCGTTATGGATTCAAGTGCAAGCAGTCGATAAAGGGATTGAAGTACTTGTAACGAAAGCAGAACTT
TCAAAGGATGGACAAAAGCTAGAACTACCAATAGGTGTAGATAAAATTATAGACATTCCTCTAGATGAAGGCATTGAATC
ATTATTCCAGCAAGAATTAGTGGAAGAGGTAGAAGAACAAGCAGGAACAAACTTTAACGAAGATGGTACGTTTGGCTTTT
TAATTAAGTTTAATGATTTTGAAGATGTCATTTCATTAAGTCATCGTCTTATCTTTGAAGATATAAAAGATGAGCTGTAT
TCATTTGAGGACCGCTATTATGTATATGTGGAATTCGATGAAGTGCTACATGATGAGGAAGAAATTGATCGCATTTTAAG
TATTGTTTTAGAATACGGAGAAGAATCAACTTTAACAATTCATCGTGTAAGTGAGTATGGGAAACAAATTGTGAAAGAGC
ATGCGCTTGAAACAATTCGCAATAATTTTCCTGCTAAAACGTAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q81TR3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

56.14

100

0.564