Detailed information    

insolico Bioinformatically predicted

Overview

Name   comH   Type   Machinery gene
Locus tag   SPG78_RS07310 Genome accession   NZ_CP140483
Coordinates   1504912..1506345 (-) Length   477 a.a.
NCBI ID   WP_000751688.1    Uniprot ID   A0AAI7ZX54
Organism   Helicobacter pylori strain 51N     
Function   import of DNA into the periplasm (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1485071..1511349 1504912..1506345 within 0


Gene organization within MGE regions


Location: 1485071..1511349
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPG78_RS07225 - 1485071..1485508 (-) 438 WP_000248397.1 Panacea domain-containing protein -
  SPG78_RS07230 - 1485732..1487360 (-) 1629 Protein_1401 RNA-directed DNA polymerase -
  SPG78_RS07235 - 1487371..1487892 (-) 522 WP_000413030.1 hypothetical protein -
  SPG78_RS07240 - 1487893..1491057 (-) 3165 WP_000965761.1 class I SAM-dependent DNA methyltransferase -
  SPG78_RS07245 - 1491058..1491765 (-) 708 WP_000589116.1 hypothetical protein -
  SPG78_RS07250 - 1491892..1494046 (-) 2155 Protein_1405 hypothetical protein -
  SPG78_RS07255 - 1494109..1494966 (-) 858 Protein_1406 hypothetical protein -
  SPG78_RS07260 - 1495057..1495710 (+) 654 WP_001042543.1 IS607-like element IS607 family transposase -
  SPG78_RS07265 - 1495685..1496942 (+) 1258 Protein_1408 RNA-guided endonuclease InsQ/TnpB family protein -
  SPG78_RS07270 - 1496989..1499046 (-) 2058 Protein_1409 DEAD/DEAH box helicase family protein -
  SPG78_RS07275 - 1499049..1499630 (-) 582 WP_228839929.1 site-specific DNA-methyltransferase -
  SPG78_RS07280 - 1499635..1501008 (-) 1374 WP_014537410.1 site-specific DNA-methyltransferase -
  SPG78_RS07285 recG 1501047..1502912 (-) 1866 WP_001158394.1 ATP-dependent DNA helicase RecG -
  SPG78_RS07290 - 1502994..1503347 (+) 354 WP_000837003.1 hypothetical protein -
  SPG78_RS07295 - 1503351..1503986 (+) 636 WP_000668030.1 outer membrane protein -
  SPG78_RS07300 - 1503983..1504735 (-) 753 WP_000767536.1 exodeoxyribonuclease III -
  SPG78_RS07310 comH 1504912..1506345 (-) 1434 WP_000751688.1 hypothetical protein Machinery gene
  SPG78_RS07315 dnaA 1506567..1507934 (-) 1368 WP_000380587.1 chromosomal replication initiator protein DnaA -
  SPG78_RS07320 - 1508086..1508622 (+) 537 WP_014537411.1 purine-nucleoside phosphorylase -
  SPG78_RS07325 - 1508669..1508908 (+) 240 WP_000461845.1 DUF2443 domain-containing protein -
  SPG78_RS07330 glmS 1508909..1510702 (+) 1794 WP_000334405.1 glutamine--fructose-6-phosphate transaminase (isomerizing) -
  SPG78_RS07335 thyX 1510723..1511349 (+) 627 WP_000451936.1 FAD-dependent thymidylate synthase -

Sequence

Protein


Download         Length: 477 a.a.        Molecular weight: 54740.72 Da        Isoelectric Point: 7.2025

>NTDB_id=914453 SPG78_RS07310 WP_000751688.1 1504912..1506345(-) (comH) [Helicobacter pylori strain 51N]
MKKTLCLSFFLTFSNPLQALVIELLEEVKTSPHKGTFKAKVLDSKEPRQVLGVYNISPHKKLTLTITHISTAIVYQPLDE
KLSLEMILNPNRPTIPRNTQIVFSSKELKEPHQMPSLNAPIQKPQNKPTSSQQSLQNFPYTESKLGSKNPKNSLLQPLAT
PNKISSANEVKTPTNDTKPPLKHSSEDQENNLFVAPPTEKTLPNNTPNANINEHNESNENRDSVEKQAIRDPNVKEFACG
KWVYDDENLQAYRPSILKRVDEDKQTATDITPCDYSNAENKSGKITTPYTKISVHKTEPLEEPQTFEAKNNFTILQARSS
TEKCKRARARKDGTTRQCYLIEEPLKQAWESEYEITTQLVKATYERPKQDDQTEPTFYETSELAYSSTRKSEITHNELNL
NEKFMEFVEVYERHYLNDIVKESSEYKEWVKNHVRFKEGVCMVLEIEEQPRAKSTPLSIENSRVVCVKKGNYLFNEV

Nucleotide


Download         Length: 1434 bp        

>NTDB_id=914453 SPG78_RS07310 WP_000751688.1 1504912..1506345(-) (comH) [Helicobacter pylori strain 51N]
ATGAAAAAAACCCTTTGTCTGTCTTTCTTTCTGACTTTCTCTAACCCTCTTCAAGCCCTTGTGATCGAGCTTTTAGAAGA
AGTCAAAACTTCGCCGCATAAAGGCACTTTTAAGGCTAAAGTCCTTGATTCTAAAGAACCAAGACAAGTTTTAGGCGTTT
ATAATATCTCCCCACACAAAAAACTCACGCTCACTATCACCCACATATCCACTGCAATTGTCTATCAACCCCTTGATGAA
AAACTTTCTTTAGAAATGATCTTAAACCCTAACCGCCCTACTATTCCTAGAAACACCCAAATTGTTTTTTCTTCAAAAGA
ATTGAAAGAGCCACACCAAATGCCTTCTTTAAACGCGCCCATACAAAAACCACAAAACAAACCCACTTCATCGCAACAAT
CTCTTCAAAACTTTCCTTACACAGAGTCCAAACTAGGCTCTAAAAACCCTAAAAACAGCCTTTTACAGCCTTTAGCCACT
CCTAATAAAATAAGCTCCGCTAATGAAGTTAAAACACCAACAAACGACACTAAACCCCCTTTAAAGCATTCTTCAGAAGA
TCAAGAAAACAACCTCTTTGTAGCACCACCCACTGAAAAAACGCTCCCTAACAACACCCCTAACGCTAATATTAATGAAC
ACAATGAAAGCAATGAAAATAGGGATAGTGTGGAAAAACAAGCGATTAGAGATCCTAATGTTAAAGAATTTGCGTGCGGG
AAGTGGGTCTATGATGATGAAAATCTACAAGCCTATCGCCCAAGCATTTTAAAACGCGTTGATGAAGACAAACAGACTGC
GACAGACATTACCCCTTGCGACTACAGCAACGCTGAAAATAAAAGCGGTAAAATCACTACCCCCTATACTAAAATCTCTG
TTCATAAAACAGAGCCTTTAGAAGAGCCGCAAACTTTTGAAGCTAAAAACAATTTTACCATCCTCCAAGCCAGAAGCTCT
ACAGAAAAATGCAAAAGAGCCAGAGCGCGAAAAGACGGCACGACTAGGCAATGCTATCTCATAGAAGAGCCTTTAAAACA
AGCGTGGGAGAGTGAGTATGAAATCACCACGCAATTAGTGAAAGCCACTTATGAGCGCCCCAAACAAGACGATCAAACAG
AGCCGACTTTCTATGAAACTAGCGAATTGGCTTATTCTTCCACACGAAAAAGCGAAATAACGCATAATGAATTGAATTTG
AATGAAAAGTTCATGGAATTTGTGGAAGTGTATGAGAGGCATTATTTAAACGATATAGTCAAAGAAAGCAGTGAATACAA
AGAATGGGTTAAAAACCATGTGCGCTTTAAAGAAGGGGTGTGCATGGTTTTAGAAATAGAAGAGCAACCACGAGCCAAAA
GCACGCCTTTGAGTATTGAAAACTCTCGTGTTGTTTGTGTCAAAAAGGGGAATTATTTATTCAACGAAGTTTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comH Helicobacter pylori 26695

91.649

100

0.92