Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   L6450_RS02285 Genome accession   NZ_AP025340
Coordinates   446161..446799 (+) Length   212 a.a.
NCBI ID   WP_003180627.1    Uniprot ID   A0A6I7TLB4
Organism   Bacillus paralicheniformis strain J36TS2     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 441161..451799
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L6450_RS02255 - 441808..442875 (+) 1068 WP_020450934.1 ABC transporter ATP-binding protein -
  L6450_RS02260 - 442877..443800 (+) 924 WP_020450935.1 ABC transporter ATP-binding protein -
  L6450_RS02265 - 444031..444609 (+) 579 WP_003180619.1 GNAT family N-acetyltransferase -
  L6450_RS02270 spxA 444787..445182 (+) 396 WP_003180621.1 transcriptional regulator SpxA -
  L6450_RS02275 - 445213..445875 (-) 663 WP_020450936.1 TerC family protein -
  L6450_RS02280 - 446054..446179 (+) 126 Protein_437 hypothetical protein -
  L6450_RS02285 mecA 446161..446799 (+) 639 WP_003180627.1 adaptor protein MecA Regulator
  L6450_RS02290 - 447037..448341 (+) 1305 WP_020450937.1 glycosyl hydrolase family 8 -
  L6450_RS02295 - 448564..449580 (+) 1017 WP_041817434.1 tripartite tricarboxylate transporter substrate binding protein -
  L6450_RS02300 - 449683..450138 (+) 456 WP_020450939.1 tripartite tricarboxylate transporter TctB family protein -
  L6450_RS02305 - 450161..451666 (+) 1506 WP_020450940.1 tripartite tricarboxylate transporter permease -

Sequence

Protein


Download         Length: 212 a.a.        Molecular weight: 25044.99 Da        Isoelectric Point: 4.1840

>NTDB_id=91371 L6450_RS02285 WP_003180627.1 446161..446799(+) (mecA) [Bacillus paralicheniformis strain J36TS2]
MEIERINEHTVKFYISYGDIEDRGFDREEIWYNRERSEELFWEMMDEVHEEEEFAVEGPLWIQVQALDKGLEIIVTRAQL
SKDGQKLELPIPEDKKQHVAEESLDALLDDFQKEEQAEEQKLQFVLKFDDFEDLISLSKMSISGCQTTLYSHENRYYLFV
DFSELPDEEVENQLSILLEYASESKTTIHMLKEYGTLIAADHALHTIKKHFA

Nucleotide


Download         Length: 639 bp        

>NTDB_id=91371 L6450_RS02285 WP_003180627.1 446161..446799(+) (mecA) [Bacillus paralicheniformis strain J36TS2]
ATGGAAATCGAAAGAATAAACGAACATACGGTTAAGTTTTATATTTCCTACGGTGATATCGAAGACCGCGGGTTTGACAG
AGAAGAAATTTGGTACAATCGAGAACGCAGTGAAGAGCTTTTTTGGGAAATGATGGACGAAGTGCACGAAGAAGAAGAGT
TTGCCGTTGAAGGCCCCCTTTGGATTCAAGTGCAGGCCCTTGATAAGGGATTGGAAATCATTGTGACAAGAGCTCAGCTG
TCCAAAGACGGACAAAAGCTGGAACTGCCGATTCCTGAAGATAAAAAACAGCATGTAGCAGAAGAAAGCCTTGATGCTTT
GCTTGACGACTTTCAAAAAGAAGAGCAGGCAGAAGAGCAGAAACTGCAGTTTGTTTTAAAGTTTGACGATTTTGAGGATT
TAATCTCACTGTCAAAAATGTCTATCAGCGGCTGCCAAACGACATTGTACTCTCACGAGAACCGCTATTATTTATTCGTG
GATTTCAGTGAACTGCCCGATGAAGAGGTGGAAAACCAGCTGAGCATTCTGCTGGAGTATGCCTCAGAATCAAAGACGAC
GATTCATATGCTGAAAGAGTATGGAACACTGATTGCAGCGGATCATGCTCTTCATACAATAAAAAAGCACTTCGCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-207)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6I7TLB4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

82.028

100

0.84

Multiple sequence alignment