Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   U1R71_RS06335 Genome accession   NZ_CP140123
Coordinates   1218964..1219620 (+) Length   218 a.a.
NCBI ID   WP_014479448.1    Uniprot ID   A0A165B643
Organism   Bacillus subtilis strain SJTU2     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1213964..1224620
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U1R71_RS06305 (U1R71_06305) oppF 1214428..1215345 (+) 918 WP_003245567.1 oligopeptide ABC transporter ATP-binding protein OppF -
  U1R71_RS06310 (U1R71_06310) yjbB 1215453..1216670 (+) 1218 WP_072592593.1 MFS transporter -
  U1R71_RS06315 (U1R71_06315) yjbC 1216834..1217412 (+) 579 WP_003224597.1 GNAT family N-acetyltransferase -
  U1R71_RS06320 (U1R71_06320) spx 1217593..1217988 (+) 396 WP_014476435.1 transcriptional regulator Spx -
  U1R71_RS06325 (U1R71_06325) yjbE 1218031..1218687 (-) 657 WP_014479447.1 TerC family protein -
  U1R71_RS06330 (U1R71_06330) - 1218857..1218997 (+) 141 WP_119122854.1 hypothetical protein -
  U1R71_RS06335 (U1R71_06335) mecA 1218964..1219620 (+) 657 WP_014479448.1 adaptor protein MecA Regulator
  U1R71_RS06340 (U1R71_06340) - 1219615..1219737 (-) 123 WP_003245684.1 hypothetical protein -
  U1R71_RS06345 (U1R71_06345) coiA 1219781..1220932 (+) 1152 WP_014479449.1 competence protein CoiA Machinery gene
  U1R71_RS06350 (U1R71_06350) pepF 1221162..1222991 (+) 1830 WP_173401378.1 oligoendopeptidase F -
  U1R71_RS06355 (U1R71_06355) - 1223029..1223196 (-) 168 WP_003244944.1 hypothetical protein -
  U1R71_RS06360 (U1R71_06360) spxH 1223511..1224410 (-) 900 WP_003245184.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25733.66 Da        Isoelectric Point: 4.1174

>NTDB_id=912912 U1R71_RS06335 WP_014479448.1 1218964..1219620(+) (mecA) [Bacillus subtilis strain SJTU2]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHEEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPASEDLDALLDDFQKEEQAVNQEEKEQKLQFVLRFGDFEDVISLSKLNVNGSKTTLYSFENR
YYLYVDFCNMTDEEVENQLSILLEYATESSISIHRLEEYGKLIISEHALEAIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=912912 U1R71_RS06335 WP_014479448.1 1218964..1219620(+) (mecA) [Bacillus subtilis strain SJTU2]
ATGGAAATTGAAAGAATTAACGAGCATACAGTAAAATTTTATATGTCTTACGGAGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATTTGGTATAACCGTGAGCGCAGTGAAGAACTATTCTGGGAAGTCATGGATGAAGTTCATGAAGAAGAGGAAT
TCGCTGTGGAAGGCCCACTTTGGATTCAAGTTCAGGCACTGGACAAAGGATTAGAAATCATCGTCACAAAAGCCCAGCTT
TCCAAAGACGGACAAAAGCTCGAACTGCCGATTCCTGAGGATAAAAAGCAAGAACCAGCATCTGAGGATCTTGACGCCTT
GCTGGATGATTTCCAGAAAGAAGAGCAAGCCGTCAATCAGGAAGAGAAGGAGCAAAAGCTTCAATTTGTCTTGCGATTTG
GCGATTTTGAGGATGTTATTTCTCTATCTAAATTGAACGTTAACGGAAGCAAAACGACTTTATATTCGTTTGAGAACCGA
TATTATTTATATGTAGATTTTTGCAATATGACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGCTGGAGTACGCAAC
TGAATCCTCAATCAGCATACACCGTCTTGAAGAGTACGGCAAGCTGATTATTTCAGAGCATGCTCTAGAAGCGATAAAAA
AACACTTTGCATCATAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-211)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A165B643

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

99.541

100

0.995