Detailed information NTG0091232

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: L6411_RS02320
• Genome accession: NZ_AP025333
• Coordinates: 452142..454364 (-)
• Length: 740 a.a.
• NCBI ID: WP_155964100.1
• Uniprot ID: -
• Organism: Streptococcus ruminantium strain GUT-189
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 447142..459364

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
L6411_RS02305 (GUT189_04050)	-	449006..450901 (-)	1896	WP_237374331.1	GAG-binding domain-containing protein	-
L6411_RS02310 (GUT189_04060)	-	451088..451396 (-)	309	WP_024532451.1	DUF1827 family protein	-
L6411_RS02315 (GUT189_04070)	-	451487..451948 (-)	462	WP_024532452.1	NUDIX hydrolase	-
L6411_RS02320 (GUT189_04080)	clpE	452142..454364 (-)	2223	WP_155964100.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
L6411_RS02325 (GUT189_04090)	-	454593..454823 (+)	231	WP_024532454.1	DUF1797 family protein	-
L6411_RS02330 (GUT189_04100)	-	454949..455638 (+)	690	WP_237373497.1	amino acid ABC transporter permease	-
L6411_RS02335 (GUT189_04110)	-	455631..456365 (+)	735	WP_155997405.1	amino acid ABC transporter ATP-binding protein	-
L6411_RS02340 (GUT189_04120)	-	456553..457401 (+)	849	WP_155997406.1	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase	-
L6411_RS02345 (GUT189_04130)	-	457899..458807 (-)	909	WP_155964098.1	neutral zinc metallopeptidase	-

Sequence

Protein

• Length: 740 a.a.
• Molecular weight: 82392.71 Da
• Isoelectric Point: 5.3516

>NTDB_id=91232 L6411_RS02320 WP_155964100.1 452142..454364(-) (clpE) [Streptococcus ruminantium strain GUT-189]
MLCKNCNINDATIHLYTNLNGKQQQVDLCHNCYQIMKTDPNNAILRGLGDMVNPNNMDPFSEFFNHLGGYPGNTPAGKKR
EQTPPTQSGGSHNGRGGQTPPPQQPNGLLEEFGINVTDIARRGDIDPVIGRDQEITRVIEILNRRTKNNPVLIGEPGVGK
TAVVEGLAQKIVDGDVPQKLRGKEVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRNRREIILFIDEIHEIVGAGSAGDGN
MDAGNILKPALARGEMQLVGATTLNEYRIIEKDAALERRMQPVKVEEPSVEETITILKGIQSKYQDYHHVKYSDTAIEAA
AVLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPREIDQRLLDAENRKAQATRDEDYEKAAYFRDQIAKYKEMQKAT
ISEEDTPLITEKEIEAIVEQKTNIPVGDLKEKEQSQLINLASDLKAHVIGQDEAVDKIAKAIRRNRVGLGAPNRPIGSFL
FVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHAIAKLVGAPPGYVGYEEAGQLTEKVRRNPYSLILLDEIEKA
HPDVLHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKIEASVGFGASIEGRTQSVLGQLSNFFTPEFMNRFDGII
EFQPLSKENLLEIVSLMLEDVNQRLSHNGINLHVTDKVKEKLVDLGYDPKMGARPLRRTIQDQIEDAITDFYLENPSEKN
LRAVMTSKGTIQIKAQTKTK

Nucleotide

• Length: 2223 bp

>NTDB_id=91232 L6411_RS02320 WP_155964100.1 452142..454364(-) (clpE) [Streptococcus ruminantium strain GUT-189]
ATGCTCTGCAAAAATTGTAATATCAACGACGCAACAATCCATCTCTATACCAATCTAAACGGTAAACAGCAACAGGTTGA
CCTCTGTCACAATTGTTATCAAATCATGAAAACAGATCCAAATAATGCTATCCTACGCGGCTTAGGTGACATGGTAAATC
CTAATAATATGGATCCATTTAGCGAGTTCTTCAATCATCTGGGAGGCTATCCAGGTAATACACCTGCTGGCAAAAAACGT
GAACAGACCCCTCCAACTCAGTCTGGCGGAAGTCACAATGGTCGTGGTGGGCAGACGCCTCCTCCACAACAGCCCAATGG
TCTCTTGGAAGAATTTGGAATCAATGTGACCGATATTGCTCGCCGAGGCGACATTGACCCAGTAATTGGTCGCGATCAAG
AAATTACACGGGTCATTGAGATTCTCAACCGCAGGACCAAAAACAATCCCGTCCTCATCGGAGAGCCAGGTGTGGGTAAG
ACTGCGGTTGTTGAAGGTCTAGCTCAAAAAATCGTTGACGGTGATGTTCCACAAAAACTGCGAGGAAAAGAGGTTATCCG
ACTCGATGTGGTAAGTTTGGTCCAAGGGACAGGCATTCGTGGGCAATTTGAAGAGCGGATGCAAAAACTGATGGAAGAAA
TCCGCAACCGCCGGGAAATCATCCTCTTTATTGATGAGATCCATGAAATCGTCGGAGCTGGTTCTGCCGGTGATGGTAAT
ATGGATGCAGGAAACATTCTCAAGCCAGCTTTGGCTCGTGGGGAAATGCAATTAGTGGGGGCAACCACCCTCAACGAATA
TCGCATCATTGAGAAGGATGCTGCTCTTGAACGACGCATGCAACCAGTAAAAGTGGAAGAACCTAGCGTTGAAGAAACAA
TCACCATTCTCAAGGGTATTCAAAGCAAATACCAAGATTATCACCACGTTAAGTATTCAGATACGGCCATTGAAGCTGCA
GCTGTTCTTTCCAACCGCTATATTCAAGACCGCTTTCTACCAGACAAGGCCATTGACCTACTGGACGAAGCCGGCTCCAA
AATGAACCTGACCCTCAACTTTGTTGACCCAAGGGAAATTGATCAGCGCTTGCTTGACGCTGAGAATCGTAAGGCTCAAG
CCACACGTGACGAAGATTATGAAAAAGCAGCTTATTTCCGCGATCAGATTGCAAAGTATAAGGAAATGCAAAAGGCTACC
ATCAGCGAAGAGGATACACCGCTCATTACCGAAAAAGAAATCGAAGCCATTGTCGAGCAAAAGACCAATATCCCTGTTGG
TGATTTGAAAGAAAAAGAACAATCACAGCTCATCAATCTAGCAAGCGATCTAAAAGCGCATGTTATCGGTCAAGATGAGG
CCGTTGATAAGATTGCAAAGGCTATCCGCCGTAATCGTGTCGGTCTGGGAGCACCAAATCGCCCAATCGGCTCCTTCCTC
TTTGTTGGTCCGACTGGCGTCGGAAAAACAGAATTGTCCAAACAACTCGCCATTGAACTCTTTGGATCGGCAGACAGCAT
GATTCGCTTTGATATGTCCGAATACATGGAAAAACACGCTATTGCCAAGTTAGTCGGGGCACCCCCAGGCTATGTCGGTT
ATGAAGAAGCAGGACAACTAACAGAAAAAGTCCGTCGCAATCCTTATTCGCTCATCCTCTTAGATGAGATAGAAAAGGCT
CATCCGGATGTCTTACACATGTTCCTCCAAGTCTTGGATGATGGGCGTCTGACAGACGGACAAGGGCGGACAGTCAGCTT
TAAAGACACCATCATCATCATGACGTCCAATGCGGGAACAGGTAAGATTGAAGCCAGCGTTGGTTTTGGTGCCAGCATAG
AAGGACGGACACAATCTGTCCTCGGTCAACTCAGCAACTTCTTTACCCCAGAGTTCATGAATCGTTTTGATGGGATTATC
GAATTCCAACCGCTCAGCAAGGAAAATCTACTAGAAATCGTCAGCCTCATGTTGGAGGATGTCAACCAGCGGCTTTCTCA
CAACGGTATCAACCTACATGTCACAGATAAGGTCAAGGAAAAATTGGTTGACTTGGGCTACGACCCAAAAATGGGAGCTC
GTCCGCTTCGCCGAACTATCCAAGATCAAATTGAGGACGCTATTACTGATTTTTATCTGGAAAATCCAAGTGAAAAGAAC
CTGCGAGCAGTCATGACGAGCAAGGGAACTATCCAAATCAAAGCTCAAACAAAAACCAAATAA

Domains

Predicted by InterproScan.

• ATPase family associated with various cellular activities (AAA) (AAA) (151-270)

• AAA lid domain (AAA_lid_9) (289-387)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (645-720)

• AAA domain (Cdc48 subfamily) (AAA_2) (474-637)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus pneumoniae Rx1	82.29	100	0.835
clpE	Streptococcus pneumoniae D39	82.29	100	0.835
clpE	Streptococcus pneumoniae R6	82.29	100	0.835
clpE	Streptococcus pneumoniae TIGR4	82.29	100	0.835
clpE	Streptococcus mutans UA159	81.684	100	0.826
clpC	Lactococcus lactis subsp. cremoris KW2	77.317	97.703	0.755
clpC	Bacillus subtilis subsp. subtilis str. 168	50.744	90.811	0.461
clpC	Streptococcus thermophilus LMD-9	47.656	86.486	0.412
clpC	Streptococcus thermophilus LMG 18311	47.344	86.486	0.409
clpC	Streptococcus pneumoniae TIGR4	47.68	84.459	0.403
clpC	Streptococcus pneumoniae Rx1	47.68	84.459	0.403
clpC	Streptococcus pneumoniae D39	47.68	84.459	0.403
clpC	Streptococcus mutans UA159	47.512	84.189	0.4
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	46.08	84.459	0.389