Detailed information NTG0911968

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: ABWX03_RS12305
• Genome accession: NZ_CP159519
• Coordinates: 2603249..2605828 (-)
• Length: 859 a.a.
• NCBI ID: WP_001210050.1
• Uniprot ID: V5VGK1
• Organism: Acinetobacter baumannii strain NAB01B-R1
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 2598249..2610828

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABWX03_RS12285 (ABWX03_12285)	-	2599206..2599550 (-)	345	WP_000654268.1	hypothetical protein	-
ABWX03_RS12290 (ABWX03_12290)	rlmKL	2599789..2601993 (+)	2205	WP_001098013.1	bifunctional 23S rRNA (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA (guanine(2445)-N(2))-methyltransferase RlmL	-
ABWX03_RS12295 (ABWX03_12295)	-	2602019..2602435 (-)	417	WP_001060738.1	hypothetical protein	-
ABWX03_RS12300 (ABWX03_12300)	-	2602704..2603192 (+)	489	WP_000941316.1	CinA family protein	-
ABWX03_RS12305 (ABWX03_12305)	clpC	2603249..2605828 (-)	2580	WP_001210050.1	ATP-dependent chaperone ClpB	Regulator
ABWX03_RS12310 (ABWX03_12310)	-	2606130..2606936 (+)	807	WP_001237344.1	peptidoglycan DD-metalloendopeptidase family protein	-
ABWX03_RS12315 (ABWX03_12315)	-	2606933..2607358 (-)	426	WP_001026230.1	GNAT family N-acetyltransferase	-
ABWX03_RS12320 (ABWX03_12320)	-	2607450..2607872 (-)	423	WP_001195082.1	OsmC family protein	-
ABWX03_RS12325 (ABWX03_12325)	-	2607951..2608070 (-)	120	Protein_2413	hypothetical protein	-
ABWX03_RS12330 (ABWX03_12330)	crp	2608311..2608976 (+)	666	WP_000203219.1	cAMP-activated global transcriptional regulator CRP	Regulator
ABWX03_RS12335 (ABWX03_12335)	-	2609033..2610123 (+)	1091	WP_085940413.1	IS4-like element ISAba1 family transposase	-

Sequence

Protein

• Length: 859 a.a.
• Molecular weight: 95142.36 Da
• Isoelectric Point: 4.9733

>NTDB_id=911968 ABWX03_RS12305 WP_001210050.1 2603249..2605828(-) (clpC) [Acinetobacter baumannii strain NAB01B-R1]
MRFEKFTNRLQQALSDAQSLAMGKDHTAIAGIHILSTLLEEPSNISLLQQAGARLPELKQKLEQALKDAPTIANPTGDVN
LNPEAVKALNLADRYAQKAGDEFLSTDWVLLGLAETGETKNILSAVGVTPDSLRKVIENIRGSDKVMSNNHEDQRDSLNK
YTIDLTERALSGKLDPVIGRDDEIRRTIQVLSRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPEGLKNKRVLSLDLG
SLLAGAKYRGEFEERLKAVLKDLAKHEGEIILFIDELHTLVGAGKGDGAMDAGNMLKPALARGELRCVGATTLDEYRQYI
EKDAALERRFQKVLVDEPSVEDTIAILRGLKEKYATHHGVQILDSAIIAAAKMSHRYITDRQLPDKAIDLIDEAASRIKM
EIDSKPEALDKLDRRLIQLKMQLEAVKKDEDAGSKAEVTHLEKQIAEVEKEYNDLEEVWKAEKTLVEGTKQAQVELDKAR
IAFEKAQREGDLAEAARLQYGVIPELQKQLEQDEVAEENEEPKLIRTKVTENEIAEVVSAATGIPVAKMMQGEREKLLHM
EEFLHDRVVGQDEAVVAVSNAVRRSRAGLSDPNRPSGSFLFLGPTGVGKTELTKALANFLFDSDDAMIRIDMSEFMEKHS
VSRLVGAPPGYVGYEEGGVLTEAVRRKPYSVVLFDEVEKAHPDVFNILLQVLDDGRLTDSQGRVVDFKNTVIVMTSNLGS
QDVRELGEGATDDEVRTIVMNAVSQHFRPEFINRIDELVIFHSLKKAQIRGIADIQLDRLRSRLVDRDMSLTVDDSAFDL
LIDAGFDPVYGARPLKRAIQQQVENTLAQKILSGDFVAGDTILVKGENGHLVFDKLKLS

Nucleotide

• Length: 2580 bp

>NTDB_id=911968 ABWX03_RS12305 WP_001210050.1 2603249..2605828(-) (clpC) [Acinetobacter baumannii strain NAB01B-R1]
ATGCGATTTGAAAAATTTACGAACCGCTTGCAGCAAGCCCTCTCAGATGCTCAATCCTTAGCGATGGGTAAAGACCATAC
AGCTATAGCAGGTATTCATATTTTGAGTACTTTATTGGAAGAGCCGTCCAATATTAGTTTGTTGCAACAAGCAGGTGCAC
GGTTACCTGAACTTAAACAAAAGCTAGAGCAGGCTTTAAAAGATGCTCCGACTATTGCTAACCCGACGGGCGATGTCAAT
TTAAACCCAGAAGCAGTTAAAGCACTCAACTTGGCAGATCGATACGCGCAAAAAGCTGGCGATGAATTTTTGTCAACTGA
CTGGGTTTTATTGGGCTTGGCAGAAACTGGTGAAACAAAAAATATTTTAAGTGCCGTAGGTGTAACTCCCGACAGCTTAC
GCAAAGTAATTGAAAATATTCGAGGTAGTGACAAAGTCATGAGTAATAATCACGAAGACCAACGTGACTCACTTAATAAA
TATACGATTGATTTAACCGAGCGGGCTTTATCGGGGAAACTTGATCCGGTGATTGGACGTGATGATGAGATCCGCCGTAC
CATTCAGGTCTTGTCACGCCGTACTAAAAATAACCCAGTACTCATCGGTGAACCTGGGGTAGGTAAAACCGCTATTGTTG
AAGGTTTGGCACAACGTATTGTTAATGGTGAAGTACCAGAAGGCTTAAAGAATAAACGTGTTTTATCGTTAGATTTAGGT
TCATTGCTTGCAGGTGCTAAGTATCGTGGTGAGTTTGAAGAACGTTTAAAAGCTGTTTTAAAAGATTTGGCGAAACACGA
AGGCGAAATCATCTTATTCATTGACGAGCTACATACGCTCGTTGGTGCTGGTAAAGGTGACGGCGCGATGGATGCAGGTA
ATATGTTAAAACCTGCGTTGGCTCGTGGTGAGTTGCGCTGTGTGGGTGCAACTACCTTAGATGAATATCGCCAATACATT
GAAAAAGACGCAGCCTTGGAGCGTCGTTTCCAAAAAGTGCTGGTCGATGAACCAAGTGTAGAAGATACCATTGCGATTTT
ACGTGGTCTGAAAGAAAAGTATGCGACTCACCATGGCGTACAGATTTTAGATTCAGCGATTATTGCTGCGGCGAAAATGT
CTCATCGTTATATTACAGATCGTCAATTACCGGACAAGGCGATTGACTTGATTGATGAGGCAGCTTCTCGTATTAAGATG
GAAATCGATTCTAAGCCAGAAGCACTTGATAAACTTGACCGCCGTTTAATCCAGTTGAAAATGCAATTGGAAGCGGTGAA
AAAAGATGAAGACGCAGGCAGTAAGGCCGAAGTTACTCATCTTGAAAAACAGATTGCTGAAGTCGAGAAAGAATACAACG
ATCTGGAAGAAGTGTGGAAAGCTGAGAAAACATTGGTAGAAGGCACTAAACAAGCTCAGGTTGAACTTGATAAAGCACGT
ATTGCTTTTGAAAAAGCTCAGCGCGAAGGCGATTTGGCAGAAGCAGCACGTTTGCAATATGGTGTAATTCCAGAGTTGCA
AAAACAACTTGAACAAGATGAAGTTGCTGAAGAAAACGAAGAGCCAAAACTCATTCGTACAAAAGTAACTGAAAATGAAA
TTGCCGAAGTCGTTAGTGCTGCAACAGGTATTCCGGTTGCTAAAATGATGCAAGGCGAGCGTGAAAAACTTCTTCATATG
GAAGAGTTTTTACATGACCGTGTTGTTGGGCAAGATGAAGCAGTTGTTGCGGTATCGAATGCAGTTCGTCGTTCACGTGC
CGGTTTGTCTGACCCGAATCGTCCTAGCGGATCATTCTTGTTCTTAGGACCAACAGGTGTAGGTAAAACTGAGTTAACTA
AAGCTTTAGCTAACTTCTTGTTTGACAGTGATGATGCCATGATTCGTATCGATATGAGTGAATTCATGGAGAAACATTCT
GTCAGCCGTTTAGTTGGTGCGCCTCCGGGTTACGTAGGTTACGAAGAGGGCGGTGTTTTAACCGAAGCTGTTCGCCGTAA
ACCATATAGCGTAGTGTTGTTTGATGAGGTTGAAAAAGCGCATCCAGATGTCTTCAATATCTTGCTACAAGTGTTAGACG
ATGGACGCTTAACCGACTCACAAGGTCGTGTAGTGGACTTTAAAAACACGGTTATTGTGATGACATCGAACTTGGGTTCA
CAAGATGTACGTGAACTTGGTGAAGGTGCAACTGATGATGAAGTGCGTACTATTGTAATGAATGCGGTAAGTCAGCATTT
CCGTCCGGAGTTTATTAACCGGATTGATGAGTTGGTGATTTTCCATTCACTCAAAAAAGCACAGATTCGTGGCATTGCCG
ATATTCAGTTGGACCGCTTACGCTCACGACTTGTTGATCGTGATATGAGTTTAACTGTAGATGACAGTGCATTTGACTTA
TTGATTGACGCTGGTTTTGATCCTGTATACGGAGCGCGTCCATTGAAACGTGCAATTCAACAACAGGTTGAAAATACACT
AGCTCAAAAAATCTTGTCAGGTGACTTTGTTGCGGGTGATACCATTTTAGTTAAAGGCGAAAATGGTCACTTAGTGTTTG
ATAAGCTGAAACTCAGCTAA

Domains

Predicted by InterProScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (594-757)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (764-844)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (92-142)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-66)

• ATPase family associated with various cellular activities (AAA) (AAA) (200-331)

• AAA lid domain (AAA_lid_9) (339-439)

3D structure

• AlphaFold DB: V5VGK1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	46.774	100	0.473
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	43.052	100	0.44
clpC	Streptococcus pneumoniae TIGR4	46.601	82.189	0.383
clpC	Lactococcus lactis subsp. cremoris KW2	48.886	78.347	0.383
clpE	Streptococcus mutans UA159	46.866	81.723	0.383
clpC	Streptococcus pneumoniae D39	46.459	82.189	0.382
clpC	Streptococcus pneumoniae Rx1	46.459	82.189	0.382
clpE	Streptococcus pneumoniae TIGR4	48.012	79.045	0.38
clpE	Streptococcus pneumoniae Rx1	48.012	79.045	0.38
clpE	Streptococcus pneumoniae D39	48.012	79.045	0.38
clpE	Streptococcus pneumoniae R6	48.012	79.045	0.38