Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   U0320_RS08180 Genome accession   NZ_CP139868
Coordinates   1585108..1585824 (+) Length   238 a.a.
NCBI ID   WP_000688498.1    Uniprot ID   Q2VG52
Organism   Staphylococcus aureus strain GP11     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1580108..1590824
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0320_RS08150 (U0320_08140) - 1580327..1580953 (+) 627 WP_000522384.1 nitroreductase family protein -
  U0320_RS08155 (U0320_08145) - 1581313..1582098 (+) 786 WP_000867940.1 carbon-nitrogen family hydrolase -
  U0320_RS14160 hld 1582695..1582775 (-) 81 WP_000046022.1 delta-hemolysin -
  U0320_RS08165 (U0320_08155) agrB 1583065..1583634 (+) 570 WP_001105707.1 accessory gene regulator AgrB -
  U0320_RS08170 (U0320_08160) agrD 1583631..1583771 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  U0320_RS08175 (U0320_08165) agrC 1583796..1585089 (+) 1294 Protein_1557 quorum-sensing sensor histidine kinase AgrC -
  U0320_RS08180 (U0320_08170) agrA 1585108..1585824 (+) 717 WP_000688498.1 quorum-sensing response regulator AgrA Regulator
  U0320_RS08185 (U0320_08175) - 1585896..1586005 (+) 110 Protein_1559 hypothetical protein -
  U0320_RS08190 (U0320_08180) - 1586193..1587152 (-) 960 WP_001253310.1 carbohydrate kinase family protein -
  U0320_RS08195 (U0320_08185) - 1587149..1588633 (-) 1485 WP_000141416.1 sucrose-6-phosphate hydrolase -
  U0320_RS08200 (U0320_08190) - 1588782..1589732 (-) 951 WP_000790325.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27933.91 Da        Isoelectric Point: 6.0927

>NTDB_id=911639 U0320_RS08180 WP_000688498.1 1585108..1585824(+) (agrA) [Staphylococcus aureus strain GP11]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSRDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=911639 U0320_RS08180 WP_000688498.1 1585108..1585824(+) (agrA) [Staphylococcus aureus strain GP11]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGTTTACAATTAT
TATCAAGAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q2VG52

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996