Detailed information NTG0911503

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: U0449_RS06655
• Genome accession: NZ_CP139862
• Coordinates: 1306908..1307945 (+)
• Length: 345 a.a.
• NCBI ID: WP_322397532.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 05H0020-2
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1301908..1312945

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
U0449_RS06620	yidC	1301943..1302869 (-)	927	WP_000835941.1	membrane protein insertase YidC	-
U0449_RS06625	-	1302947..1303225 (-)	279	WP_001174613.1	acylphosphatase	-
U0449_RS06630	-	1303259..1303999 (+)	741	WP_000152679.1	RNA methyltransferase	-
U0449_RS06635	-	1304055..1304738 (+)	684	WP_001016910.1	Bax inhibitor-1/YccA family protein	-
U0449_RS06640	asnA	1304850..1305842 (+)	993	WP_000747993.1	aspartate--ammonia ligase	-
U0449_RS06645	rsmD	1305907..1306446 (+)	540	WP_000706960.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
U0449_RS06650	coaD	1306436..1306924 (+)	489	WP_001280746.1	pantetheine-phosphate adenylyltransferase	-
U0449_RS06655	sepM	1306908..1307945 (+)	1038	WP_322397532.1	SepM family pheromone-processing serine protease	Regulator
U0449_RS06660	-	1308003..1308233 (+)	231	WP_000250384.1	DUF1146 family protein	-
U0449_RS06665	murA	1308257..1309540 (+)	1284	WP_000358028.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
U0449_RS06670	-	1309533..1309721 (+)	189	WP_001813390.1	DNA-directed RNA polymerase subunit beta	-
U0449_RS06675	endA	1309760..1310584 (+)	825	WP_001036786.1	DNA-entry nuclease EndA	Machinery gene
U0449_RS06680	-	1310875..1312206 (+)	1332	WP_000390043.1	hemolysin family protein	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37567.64 Da
• Isoelectric Point: 5.0772

>NTDB_id=911503 U0449_RS06655 WP_322397532.1 1306908..1307945(+) (sepM) [Streptococcus pneumoniae strain 05H0020-2]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
EIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFAPDNPVSEEEQKAHLDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=911503 U0449_RS06655 WP_322397532.1 1306908..1307945(+) (sepM) [Streptococcus pneumoniae strain 05H0020-2]
ATGAAAAAAAAGATTAGATGGCCTTTGTATGTCATTGCGGCCTTGATTGTGACCTTCTTGGCATTTGTGGTGCCTTTGCC
CTACTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCTACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GAGATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGATTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAGATTATCACCTTGGAAAATGGCAAAAATGGAATTGGAATCGGCTTGATTGACCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGTCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTGCTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCTGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.649	99.13	0.591