Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicX   Type   Regulator
Locus tag   U0448_RS09960 Genome accession   NZ_CP139860
Coordinates   1954496..1955305 (+) Length   269 a.a.
NCBI ID   WP_001289493.1    Uniprot ID   Q9RCS5
Organism   Streptococcus pneumoniae strain 21011     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1949496..1960305
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0448_RS09940 - 1950996..1951121 (-) 126 WP_001818232.1 hypothetical protein -
  U0448_RS09945 mutY 1951218..1952393 (+) 1176 WP_081570899.1 A/G-specific adenine glycosylase -
  U0448_RS09950 micA 1952448..1953152 (+) 705 WP_000722076.1 response regulator YycF Regulator
  U0448_RS09955 micB 1953145..1954494 (+) 1350 WP_000886210.1 cell wall metabolism sensor histidine kinase VicK Regulator
  U0448_RS09960 vicX 1954496..1955305 (+) 810 WP_001289493.1 MBL fold metallo-hydrolase Regulator
  U0448_RS09965 relB 1955396..1955638 (+) 243 WP_000208080.1 type II toxin-antitoxin system RelB family antitoxin -
  U0448_RS09970 - 1955640..1955894 (+) 255 WP_050221040.1 type II toxin-antitoxin system RelE/ParE family toxin -
  U0448_RS09975 - 1955941..1956714 (+) 774 WP_000731132.1 ion transporter -
  U0448_RS09980 - 1956974..1957960 (-) 987 WP_000204727.1 L-lactate dehydrogenase -

Sequence

Protein


Download         Length: 269 a.a.        Molecular weight: 29916.89 Da        Isoelectric Point: 6.1743

>NTDB_id=911376 U0448_RS09960 WP_001289493.1 1954496..1955305(+) (vicX) [Streptococcus pneumoniae strain 21011]
MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLLAEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMD
LYANEKTWQAMENSKYLGKVDSSQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKKIYLGHLSKENNIKELAHMTMVN
QLAQADLGVGVDFKVYDTSPDTATPLTEI

Nucleotide


Download         Length: 810 bp        

>NTDB_id=911376 U0448_RS09960 WP_001289493.1 1954496..1955305(+) (vicX) [Streptococcus pneumoniae strain 21011]
ATGAGTGAAATAGGCTTTAAATACAGTATTTTAGCATCGGGTTCCAGTGGAAATTCTTTTTATCTGGAAACCTCAAAAAA
GAAGCTTTTAGTGGATGCAGGCTTGTCTGGCAAGAAAATTACCAGTCTGCTAGCTGAAATTAACCGCAAGCCAGAAGACC
TGGATGCCATCTTGATTACCCATGAGCATTCAGATCATATCCATGGAGTAGGCGTTTTGGCTCGCAAGTATGGTATGGAT
CTTTATGCCAATGAAAAGACCTGGCAAGCTATGGAAAATAGTAAATATCTTGGCAAGGTGGATTCTTCGCAAAAGCATAT
TTTTGAAATGGGTAAAACCAAAACCTTTGGAGATATCGACATCGAGAGTTTTGGTGTAAGCCATGATGCAGTCGCACCGC
AGTTCTATCGCTTTATGAAGGATGATAAGAGTTTTGTCCTTTTGACAGATACAGGTTATGTCAGTGACCGTATGGCGGGC
ATTGTCGAAAATGCGGATGGCTATCTTATCGAGGCCAACCATGATGTAGAGATTTTGCGATCAGGTTCTTACGCTTGGCG
ACTCAAACAACGAATCCTATCTGACCTTGGTCACCTTTCTAACGAGGACGGTGCTGAAGCTATGATTCGGACGCTAGGAA
ATCGTACTAAGAAGATTTACCTTGGGCATTTATCTAAGGAAAATAATATCAAGGAACTGGCTCATATGACCATGGTCAAT
CAGCTGGCTCAAGCTGATCTGGGAGTCGGAGTAGACTTTAAGGTTTATGATACCTCACCAGATACCGCAACACCATTGAC
AGAGATATAG

Domains

Predicted by InterproScan.

Metallo-beta-lactamase superfamily (Lactamase_B)

(15-223)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9RCS5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicX Streptococcus mutans UA159

77.323

100

0.773