Detailed information NTG0091127

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: SUT_RS02600
• Genome accession: NZ_AP025331
• Coordinates: 501969..504191 (-)
• Length: 740 a.a.
• NCBI ID: WP_155971046.1
• Uniprot ID: -
• Organism: Streptococcus ruminantium strain GUT-183
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 496969..509191

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SUT_RS02585 (GUT183_04730)	-	498830..500728 (-)	1899	WP_237373494.1	GAG-binding domain-containing protein	-
SUT_RS02590 (GUT183_04740)	-	500915..501223 (-)	309	WP_024532451.1	DUF1827 family protein	-
SUT_RS02595 (GUT183_04750)	-	501314..501775 (-)	462	WP_165436953.1	NUDIX hydrolase	-
SUT_RS02600 (GUT183_04760)	clpE	501969..504191 (-)	2223	WP_155971046.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
SUT_RS02605 (GUT183_04770)	-	504420..504650 (+)	231	WP_024532454.1	DUF1797 family protein	-
SUT_RS02610 (GUT183_04780)	-	504776..505465 (+)	690	WP_237373497.1	amino acid ABC transporter permease	-
SUT_RS02615 (GUT183_04790)	-	505458..506192 (+)	735	WP_237373499.1	amino acid ABC transporter ATP-binding protein	-
SUT_RS02620 (GUT183_04800)	-	506381..507229 (+)	849	WP_120171389.1	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase	-
SUT_RS02625 (GUT183_04810)	-	507715..508623 (-)	909	WP_155971040.1	neutral zinc metallopeptidase	-

Sequence

Protein

• Length: 740 a.a.
• Molecular weight: 82396.71 Da
• Isoelectric Point: 5.3516

>NTDB_id=91127 SUT_RS02600 WP_155971046.1 501969..504191(-) (clpE) [Streptococcus ruminantium strain GUT-183]
MLCKNCNINDATIHLYTNLNGKQQQVDLCHNCYQIMKTDPNNAILRGLGDMVNPNNMDPFSEFFNHLGGYPGNTPAGKKR
EQTPPTQSGGSHNGRGGQTPPPQQPNGLLEEFGINVTDIARRGDIDPVIGRDQEITRVIEILNRRTKNNPVLIGEPGVGK
TAVVEGLAQKIVDGDVPQKLRGKEVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRNRREIILFIDEIHEIVGAGSAGDGN
MDAGNILKPALARGEMQLVGATTLNEYRIIEKDAALERRMQPVKVEEPSVEETITILKGIQSKYQDYHHVKYSDTAIEAA
AVLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPREIDQRLLDAENRKAQATRDEDYEKAAYFRDQIAKYKEMQKAT
ISEEDTPLITEKEIEAIVEQKTNIPVGDLKEKEQSQLINLASDLKAHVIGQDEAVDKIAKAIRRNRVGLGAPNRPIGSFL
FVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHAIAKLVGAPPGYVGYEEAGQLTEKVRRNPYSLILLDEIEKA
HPDVLHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKVEASVGFGASMEGRTQSVLGQLSNFFTPEFMNRFDGII
EFQPLSKENLLEIVSLMLEDVNQRLSHNGINLHVTDKVKEKLVDLGYDPKMGARPLRRTIQDQIEDAITDFYLENPSEKN
LRAVMTSKGTIQIKAQTKTK

Nucleotide

• Length: 2223 bp

>NTDB_id=91127 SUT_RS02600 WP_155971046.1 501969..504191(-) (clpE) [Streptococcus ruminantium strain GUT-183]
ATGCTCTGCAAAAATTGTAATATCAACGACGCAACAATCCATCTCTATACCAATCTAAACGGTAAACAGCAACAGGTTGA
CCTCTGTCACAATTGTTATCAAATCATGAAAACAGATCCAAATAATGCTATCCTACGCGGCTTAGGTGACATGGTAAATC
CTAATAATATGGATCCATTTAGCGAGTTCTTCAATCATCTGGGAGGCTATCCAGGTAATACACCTGCTGGCAAAAAACGT
GAACAGACCCCTCCAACTCAGTCTGGCGGAAGTCACAATGGTCGTGGTGGGCAGACGCCTCCTCCACAACAGCCCAATGG
TCTCTTGGAAGAATTTGGAATCAATGTGACCGATATTGCTCGCCGAGGCGACATTGACCCAGTAATTGGTCGCGATCAAG
AAATTACACGGGTCATTGAGATTCTCAACCGCAGGACCAAAAACAATCCCGTCCTCATCGGAGAGCCAGGTGTGGGGAAG
ACTGCGGTTGTTGAAGGTCTAGCTCAAAAAATCGTTGACGGTGATGTTCCACAAAAACTGCGAGGAAAAGAGGTTATCCG
ACTCGATGTGGTAAGTTTGGTCCAAGGGACAGGCATTCGTGGGCAATTTGAAGAGCGGATGCAAAAACTGATGGAAGAAA
TCCGCAACCGCCGGGAAATCATCCTCTTTATTGATGAGATCCATGAAATCGTCGGAGCTGGTTCTGCCGGTGATGGTAAT
ATGGATGCAGGAAACATTCTCAAGCCAGCTTTGGCTCGTGGGGAAATGCAATTAGTGGGGGCAACCACCCTCAACGAATA
TCGCATCATTGAGAAGGATGCTGCTCTTGAACGACGCATGCAACCAGTAAAAGTGGAAGAACCTAGCGTTGAAGAAACAA
TCACCATTCTCAAGGGTATTCAAAGCAAATACCAAGATTATCACCACGTTAAGTATTCAGATACGGCCATTGAAGCTGCA
GCTGTTCTTTCCAATCGCTATATTCAAGACCGCTTTCTACCAGACAAGGCCATTGACCTACTGGACGAAGCCGGCTCCAA
AATGAACCTGACCCTCAACTTTGTTGACCCAAGGGAAATTGATCAGCGCTTGCTTGACGCTGAGAATCGTAAGGCTCAAG
CCACACGTGACGAAGATTATGAAAAAGCAGCTTATTTCCGCGATCAGATTGCAAAGTATAAGGAAATGCAAAAGGCTACC
ATCAGCGAAGAGGATACACCGCTCATTACCGAAAAAGAAATCGAAGCCATTGTCGAGCAAAAGACCAATATCCCCGTTGG
TGATTTGAAAGAAAAAGAACAATCACAGCTCATCAATCTAGCAAGCGATCTAAAAGCGCATGTTATCGGTCAAGATGAGG
CCGTTGATAAGATTGCAAAGGCTATCCGCCGTAATCGTGTCGGTCTGGGAGCACCAAATCGCCCAATCGGCTCCTTCCTC
TTTGTTGGTCCGACTGGCGTTGGAAAAACAGAATTGTCCAAACAACTCGCCATTGAACTCTTTGGATCGGCGGACAGTAT
GATTCGCTTTGATATGTCCGAATACATGGAAAAACACGCTATTGCCAAGTTAGTCGGGGCACCCCCAGGCTATGTCGGTT
ATGAAGAAGCAGGACAACTAACAGAAAAAGTTCGCCGCAATCCTTATTCACTCATCCTCTTAGATGAGATAGAAAAGGCC
CATCCGGATGTCTTACACATGTTCCTCCAAGTCTTGGATGATGGGCGTTTGACAGACGGACAAGGACGGACAGTCAGCTT
TAAAGACACCATCATCATCATGACGTCCAATGCGGGAACAGGTAAGGTTGAAGCCAGCGTTGGTTTTGGTGCCAGCATGG
AAGGACGGACACAATCTGTCCTCGGTCAACTCAGCAACTTCTTTACCCCAGAGTTCATGAATCGTTTTGATGGGATTATC
GAATTCCAACCGCTCAGCAAGGAAAATCTACTAGAAATCGTCAGCCTCATGTTGGAGGATGTCAACCAGCGGCTTTCTCA
CAACGGTATCAACCTACATGTCACAGATAAGGTCAAGGAAAAATTGGTTGACTTGGGCTACGACCCAAAAATGGGAGCTC
GTCCGCTTCGCCGAACTATCCAAGATCAAATTGAGGACGCTATTACTGATTTTTATCTGGAAAATCCAAGTGAAAAGAAC
CTGCGAGCAGTCATGACGAGCAAGGGAACTATCCAAATCAAGGCTCAAACAAAAACCAAATAA

Domains

Predicted by InterproScan.

• ATPase family associated with various cellular activities (AAA) (AAA) (151-270)

• AAA lid domain (AAA_lid_9) (289-387)

• AAA domain (Cdc48 subfamily) (AAA_2) (474-637)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (645-720)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus pneumoniae Rx1	82.29	100	0.835
clpE	Streptococcus pneumoniae D39	82.29	100	0.835
clpE	Streptococcus pneumoniae R6	82.29	100	0.835
clpE	Streptococcus pneumoniae TIGR4	82.29	100	0.835
clpE	Streptococcus mutans UA159	81.684	100	0.826
clpC	Lactococcus lactis subsp. cremoris KW2	77.455	97.703	0.757
clpC	Bacillus subtilis subsp. subtilis str. 168	50.744	90.811	0.461
clpC	Streptococcus thermophilus LMD-9	47.434	86.892	0.412
clpC	Streptococcus thermophilus LMG 18311	47.123	86.892	0.409
clpC	Streptococcus pneumoniae TIGR4	47.68	84.459	0.403
clpC	Streptococcus pneumoniae Rx1	47.68	84.459	0.403
clpC	Streptococcus pneumoniae D39	47.68	84.459	0.403
clpC	Streptococcus mutans UA159	47.673	84.189	0.401
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	46.178	84.865	0.392