Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutS/mutS2   Type   Machinery gene
Locus tag   ABQ274_RS00960 Genome accession   NZ_CP159281
Coordinates   183401..185731 (+) Length   776 a.a.
NCBI ID   WP_003129443.1    Uniprot ID   Q9CF36
Organism   Lactococcus lactis strain FNZ339     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 178401..190731
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABQ274_RS00940 (ABQ274_00940) - 179232..180320 (-) 1089 WP_003129448.1 Xaa-Pro peptidase family protein -
  ABQ274_RS00945 (ABQ274_00945) ccpA 180535..181533 (+) 999 WP_353727366.1 catabolite control protein A Regulator
  ABQ274_RS00950 (ABQ274_00950) - 181671..182636 (+) 966 WP_003129446.1 NAD(P)/FAD-dependent oxidoreductase -
  ABQ274_RS00955 (ABQ274_00955) - 182796..183356 (+) 561 WP_003129445.1 CvpA family protein -
  ABQ274_RS00960 (ABQ274_00960) mutS/mutS2 183401..185731 (+) 2331 WP_003129443.1 endonuclease MutS2 Machinery gene
  ABQ274_RS00965 (ABQ274_00965) trxA 185828..186142 (+) 315 WP_003129442.1 thioredoxin -
  ABQ274_RS00970 (ABQ274_00970) - 186386..186589 (+) 204 WP_010906074.1 DUF2969 domain-containing protein -
  ABQ274_RS00980 (ABQ274_00980) aroD 186852..187532 (+) 681 WP_003129440.1 type I 3-dehydroquinate dehydratase -
  ABQ274_RS00985 (ABQ274_00985) purB 187729..189024 (+) 1296 WP_023164397.1 adenylosuccinate lyase -
  ABQ274_RS00990 (ABQ274_00990) - 189159..190142 (+) 984 WP_003129438.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 776 a.a.        Molecular weight: 87296.22 Da        Isoelectric Point: 6.9607

>NTDB_id=911138 ABQ274_RS00960 WP_003129443.1 183401..185731(+) (mutS/mutS2) [Lactococcus lactis strain FNZ339]
MNKKILQILEYDKVKEQFMNALTTAQGQQELKDLKPLTDKEKIQLLFDEVADFRLLTQENGLLNLGKTNDLTEILRRLEL
EASLSGKEFVEIKKVIQLGINIQRFFDEAENVETPSLAITLEKLVDLSALVKKLEIFDNAGSLYDNASLELMHIRASIKS
HQSEIRKIMQEMLTKNLSSLSENVITIRNDRQVLPVKAENKNKIAGVVHDMSASGQTLYIEPNAVVSLNNKLNQKRIEER
QEITRIYRELASQLKPYSFDIRQNAWLIGHIDFVRAKYLYLAANKATLPELTTDKDITLFAARHPLIEAKIVVTNDIKFD
AGLNTIVITGPNTGGKTITLKTVGLLTILAQSGLPILAADGSRIHLFDDIFADIGDEQSIEQSLSTFSSHMTNIVHILAQ
ADENSLVLFDELGAGTDPKEGAALAIAILENLRERNVKTMASTHYPELKAYGVETQRVINASMEFNIDKMQPTYHLQLGV
PGRSNALEISRRLGLPETIISVASQQISDSEHDVNQMIEKLEEKTREVIESSRNIKKIERENQSLHKDLTKVYNQINRER
EFELEKAQKEAQEVVKKASLEAQEILKNLNDKAALKPHEIIAARKELEGLAPTIDFSKNKVLKKAKAQRGLKQGAEVNVT
SYGQRGKLIRLEKDGRWTVQMGSITTRLNEDEFEVIESPEQIQAKTKNVSKKVTSKVKAQLDLRGMRYEEAELELDNYID
QALLANLIQITIVHGIGTGVIREMVQKKLQKHRHIKSYEYAPINAGGSGATIAILK

Nucleotide


Download         Length: 2331 bp        

>NTDB_id=911138 ABQ274_RS00960 WP_003129443.1 183401..185731(+) (mutS/mutS2) [Lactococcus lactis strain FNZ339]
ATGAATAAAAAAATTCTCCAAATATTGGAATATGATAAAGTCAAAGAACAGTTTATGAATGCTTTGACGACAGCGCAGGG
TCAACAAGAATTAAAAGATTTAAAACCTTTGACAGATAAGGAAAAAATTCAGCTCCTTTTTGATGAAGTTGCTGATTTTC
GCTTATTGACCCAAGAAAATGGCCTATTAAATTTAGGAAAAACAAATGATTTAACAGAAATACTCAGACGTCTAGAGCTT
GAAGCCAGTCTTTCAGGCAAGGAATTCGTTGAAATAAAAAAAGTGATTCAATTAGGGATTAATATTCAACGCTTTTTTGA
TGAAGCTGAAAATGTTGAAACACCTTCACTAGCTATTACTTTGGAAAAATTGGTTGATTTATCAGCATTAGTCAAAAAAT
TAGAAATTTTTGATAATGCGGGAAGTCTTTATGATAATGCCAGTCTCGAATTGATGCATATCCGTGCTTCAATCAAGAGT
CATCAATCAGAAATTCGGAAAATCATGCAGGAAATGCTGACCAAAAATCTCTCATCTTTGAGTGAAAATGTCATCACTAT
CCGAAATGACCGACAAGTGCTTCCTGTAAAAGCAGAAAACAAAAATAAAATTGCTGGTGTAGTTCATGATATGTCTGCTT
CAGGTCAAACGCTTTATATTGAACCAAATGCGGTTGTTTCATTAAATAATAAACTTAATCAAAAGAGAATTGAAGAACGC
CAAGAAATCACAAGAATTTATCGTGAGCTTGCTAGTCAATTAAAACCTTATAGCTTTGATATAAGACAAAATGCTTGGCT
GATTGGTCATATTGATTTTGTTCGTGCCAAGTATCTTTATTTAGCAGCGAATAAAGCGACACTTCCAGAATTAACAACCG
ATAAAGATATTACCCTTTTTGCAGCTCGCCATCCTTTGATTGAAGCAAAAATAGTTGTGACAAATGATATTAAATTTGAT
GCAGGGCTCAATACGATTGTTATTACCGGTCCAAATACGGGTGGGAAGACCATTACTTTGAAAACAGTTGGTTTGTTGAC
AATATTGGCTCAATCAGGTCTGCCAATTTTAGCCGCTGATGGCAGTCGAATTCATCTTTTTGATGATATTTTTGCCGATA
TCGGTGATGAGCAATCCATTGAGCAAAGTTTATCAACTTTCTCAAGTCATATGACTAATATTGTTCATATTTTAGCTCAA
GCAGATGAAAATAGTTTGGTCTTGTTTGATGAACTTGGGGCAGGAACTGATCCAAAAGAAGGAGCGGCTCTTGCTATTGC
CATACTGGAAAATTTACGTGAACGAAATGTGAAAACCATGGCAAGTACTCATTATCCTGAGTTAAAAGCTTATGGGGTCG
AAACGCAACGAGTAATCAATGCAAGTATGGAATTTAACATTGATAAAATGCAACCCACTTATCATTTGCAACTGGGAGTG
CCTGGGCGTTCAAATGCCTTGGAGATTTCTAGAAGATTAGGTTTGCCAGAAACCATTATTTCAGTAGCCAGTCAACAAAT
TTCTGACAGTGAGCATGATGTCAATCAGATGATTGAAAAGTTGGAAGAAAAAACGCGTGAAGTGATTGAAAGTTCAAGAA
ATATTAAAAAAATTGAACGAGAAAATCAAAGTTTACATAAAGATTTGACGAAAGTCTATAATCAAATTAATCGCGAGCGC
GAGTTTGAATTAGAAAAAGCACAAAAAGAAGCTCAAGAAGTAGTTAAAAAAGCGAGTCTTGAAGCGCAAGAAATTTTGAA
GAATCTCAATGATAAAGCAGCGTTGAAACCACATGAAATTATTGCTGCTAGAAAAGAACTTGAAGGTTTGGCTCCAACCA
TTGATTTTTCTAAAAATAAGGTTTTGAAAAAAGCGAAAGCACAAAGAGGACTTAAGCAAGGGGCTGAAGTTAATGTCACT
TCTTATGGTCAGCGTGGTAAATTGATTCGTTTAGAAAAAGATGGACGTTGGACGGTTCAGATGGGTTCAATCACGACTCG
TTTAAATGAAGATGAATTTGAAGTGATTGAAAGTCCAGAACAAATTCAAGCCAAAACTAAAAATGTCAGCAAGAAGGTGA
CTTCTAAAGTCAAAGCTCAACTTGATTTACGCGGGATGCGTTATGAAGAAGCAGAACTGGAATTGGATAATTATATTGAC
CAAGCTCTACTTGCAAATTTGATTCAAATTACGATTGTTCATGGGATTGGAACGGGTGTTATTCGAGAAATGGTACAGAA
AAAACTTCAAAAACACCGTCATATTAAATCTTATGAATATGCACCAATTAATGCTGGTGGCTCTGGAGCAACGATTGCTA
TTTTGAAGTAA

Domains

Predicted by InterProScan.

Smr domain (Smr)

(701-776)

MutS2 and Smr-associated SH3 domain (MSSS)

(634-672)

MutS domain V (MutS_V)

(326-508)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9CF36

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutS/mutS2 Bacillus subtilis subsp. subtilis str. 168

42.621

100

0.432