Detailed information    

insolico Bioinformatically predicted

Overview

Name   degS   Type   Regulator
Locus tag   R6I59_RS19170 Genome accession   NZ_CP139744
Coordinates   3644969..3646126 (-) Length   385 a.a.
NCBI ID   WP_003227983.1    Uniprot ID   A0A199WDV9
Organism   Bacillus subtilis isolate FELIX_MS255     
Function   phosphorylation of DegU (predicted from homology)   
Competence regulation

Genomic Context

Location: 3639969..3651126
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R6I59_RS19140 (R6I59_19140) yvyF 3640222..3640641 (-) 420 WP_003227995.1 TIGR03826 family flagellar region protein -
  R6I59_RS19145 (R6I59_19145) comFC 3640715..3641437 (-) 723 WP_003227991.1 comF operon protein ComFC Machinery gene
  R6I59_RS19150 (R6I59_19150) comFB 3641401..3641697 (-) 297 WP_003227989.1 late competence protein ComFB -
  R6I59_RS19155 (R6I59_19155) comFA 3641757..3643148 (-) 1392 WP_003243962.1 ATP-dependent helicase ComFA Machinery gene
  R6I59_RS19160 (R6I59_19160) fakBA 3643254..3644099 (-) 846 WP_003244125.1 DegV family protein -
  R6I59_RS19165 (R6I59_19165) degU 3644197..3644886 (-) 690 WP_003219701.1 two-component system response regulator DegU Regulator
  R6I59_RS19170 (R6I59_19170) degS 3644969..3646126 (-) 1158 WP_003227983.1 two-component sensor histidine kinase DegS Regulator
  R6I59_RS19175 (R6I59_19175) yvyE 3646343..3646996 (+) 654 WP_003227979.1 YigZ family protein -
  R6I59_RS19180 (R6I59_19180) tagV 3646996..3648171 (+) 1176 WP_003244117.1 polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase TagV -
  R6I59_RS19185 (R6I59_19185) tagO 3648244..3649320 (-) 1077 WP_003227975.1 MraY family glycosyltransferase -
  R6I59_RS19190 (R6I59_19190) tuaH 3649465..3650658 (-) 1194 WP_003243252.1 teichuronic acid biosynthesis protein TuaH -

Sequence

Protein


Download         Length: 385 a.a.        Molecular weight: 44957.76 Da        Isoelectric Point: 6.2957

>NTDB_id=910844 R6I59_RS19170 WP_003227983.1 3644969..3646126(-) (degS) [Bacillus subtilis isolate FELIX_MS255]
MNKTKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVQTRHARNRLSEVSR
NFHRFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLREVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGAEDGFQEIKNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGETEDQRLAPQFEVALFRLAQEAVSNALKHSESEEITVKVEI
TKDFVILMIKDNGKGFDLKEAKEKKNKSFGLLGMKERVDLLEGTMTIDSKIGLGTFIMIKVPLSL

Nucleotide


Download         Length: 1158 bp        

>NTDB_id=910844 R6I59_RS19170 WP_003227983.1 3644969..3646126(-) (degS) [Bacillus subtilis isolate FELIX_MS255]
ATGAATAAAACAAAGATGGATTCCAAAGTGCTGGATTCTATTTTGATGAAGATGCTGAAAACCGTTGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGGGAGCAGTCACGCCAGCAGTATGAACAGCTGGTCGAAGAACTGAAACAAATTAAACAGCAGG
TGTATGAAGTGATTGAGCTTGGCGATAAACTTGAAGTGCAAACTCGCCATGCGAGAAACCGTTTATCCGAGGTCAGCCGT
AATTTTCATAGATTCAGTGAAGAGGAAATCCGCAATGCTTATGAAAAAGCCCATAAGCTGCAGGTAGAATTGACGATGAT
CCAGCAGCGTGAGAAGCAATTGCGCGAACGGCGGGACGATTTGGAGCGCAGATTGCTAGGGCTTCAGGAAATCATTGAGC
GGTCAGAATCATTAGTAAGCCAAATTACAGTTGTGCTCAACTACTTGAATCAGGATTTGCGCGAAGTTGGACTGCTTCTT
GCTGATGCTCAGGCAAAACAGGATTTCGGCTTAAGAATTATTGAGGCGCAGGAAGAAGAGCGAAAAAGAGTCTCAAGAGA
AATCCATGACGGACCCGCTCAAATGCTGGCGAATGTTATGATGAGATCGGAATTAATCGAGCGGATTTTCCGTGACCGGG
GCGCAGAGGACGGATTCCAAGAAATTAAAAATCTCCGCCAAAATGTTCGGAATGCCCTTTACGAAGTGAGAAGGATTATA
TATGATTTAAGACCGATGGCCCTTGATGACCTAGGCCTGATTCCAACTTTAAGAAAATATCTATATACAACCGAGGAATA
TAACGGGAAGGTCAAAATACATTTTCAGTGCATTGGAGAAACAGAGGATCAGAGGCTAGCGCCTCAGTTTGAGGTTGCGC
TCTTCAGGCTCGCACAGGAAGCTGTGTCTAATGCGCTAAAGCATTCTGAATCTGAAGAAATTACAGTCAAAGTTGAGATC
ACAAAGGATTTTGTGATTTTAATGATAAAAGATAACGGTAAAGGGTTCGACCTGAAGGAAGCGAAAGAGAAGAAAAACAA
ATCATTCGGCTTGCTGGGCATGAAAGAAAGAGTAGATTTATTGGAAGGAACGATGACAATAGATTCGAAAATAGGTCTTG
GGACATTTATTATGATTAAGGTTCCGTTATCTCTTTGA

Domains

Predicted by InterproScan.

Histidine kinase (HisKA_3)

(180-248)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(291-384)

Sensor protein DegS (DegS)

(12-170)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A199WDV9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  degS Bacillus subtilis subsp. subtilis str. 168

100

100

1