Detailed information NTG0909546

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: SM123_RS07820
• Genome accession: NZ_CP139419
• Coordinates: 1631014..1633269 (+)
• Length: 751 a.a.
• NCBI ID: WP_320909384.1
• Uniprot ID: -
• Organism: Streptococcus lingualis strain S5
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1626014..1638269

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SM123_RS07795 (SM123_07795)	-	1626775..1627770 (-)	996	WP_070845308.1	LacI family DNA-binding transcriptional regulator	-
SM123_RS07800 (SM123_07800)	-	1627797..1628675 (-)	879	WP_070845306.1	NAD(P)H-hydrate dehydratase	-
SM123_RS07805 (SM123_07805)	-	1628728..1629501 (-)	774	WP_004219876.1	HAD-IIB family hydrolase	-
SM123_RS07810 (SM123_07810)	-	1629515..1630369 (-)	855	WP_003002422.1	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase	-
SM123_RS07815 (SM123_07815)	-	1630535..1630765 (-)	231	WP_003005989.1	DUF1797 family protein	-
SM123_RS07820 (SM123_07820)	clpE	1631014..1633269 (+)	2256	WP_320909384.1	AAA family ATPase	Regulator
SM123_RS07825 (SM123_07825)	-	1633380..1633829 (+)	450	WP_155168827.1	NUDIX hydrolase	-
SM123_RS07830 (SM123_07830)	-	1633897..1634199 (+)	303	WP_155168825.1	DUF1827 family protein	-
SM123_RS07835 (SM123_07835)	ileS	1634587..1637379 (-)	2793	WP_320909385.1	isoleucine--tRNA ligase	-

Sequence

Protein

• Length: 751 a.a.
• Molecular weight: 83710.88 Da
• Isoelectric Point: 5.2208

>NTDB_id=909546 SM123_RS07820 WP_320909384.1 1631014..1633269(+) (clpE) [Streptococcus lingualis strain S5]
MLCQNCKINESTIHLYTNVNGRQQQVDLCQNCYKIMKTDPNNSFLKGMTQRSQLTGDPFEDFFNNLGNFKSPQEPQTPPT
QSGGSYGGGGYGQNNNRGGQDPRQARPQKPKGLLEEFGINVTEIARKGDIDPVIGRDEEIIRVIEILNRRTKNNPVLIGE
PGVGKTAVVEGLAQKIVDGDVPHKLQGKEVIRLDVVSLVQGTGIRGQFEERMQKLMDEIRQREDVILFIDEIHEIVGAGS
AGEGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPTVEETITILKGIQKKYEDYHHVHYTDG
AIEAAAILSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKAQATREEDFEKAAYFRDQIAKYKE
MQGQHVTDQETPVISEKTIEHIVEQKTNIPVGDLKEKEQSQLINLASDLKAHVIGQDDAVDKIAKAIRRNRVGLGSPNRP
IGSFLFVGPTGVGKTELSKQLAIELFGSADNMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRRNPYSLVLLD
EVEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKAEANVGFGAAREGRTNSVLGELGNFFSPEFMNR
FDGIIEFQPLSKENLLQIVTLMLDEVSQRLAQNEIHLDVTEKVKEKLVDLGYDPKMGARPLRRTIQDHIEDAITDYYLEH
PSEKQLKAVMTSNGKISIKSAHKPVEQTSES

Nucleotide

• Length: 2256 bp

>NTDB_id=909546 SM123_RS07820 WP_320909384.1 1631014..1633269(+) (clpE) [Streptococcus lingualis strain S5]
ATGCTTTGTCAAAATTGTAAAATAAATGAATCAACCATCCATTTATATACAAATGTAAATGGACGTCAGCAGCAAGTAGA
CCTCTGTCAAAATTGCTATAAAATTATGAAAACAGACCCTAATAACAGCTTCTTGAAAGGCATGACCCAACGTAGCCAAC
TCACTGGAGATCCTTTTGAAGATTTCTTCAATAACCTTGGAAACTTCAAAAGTCCGCAAGAACCTCAAACCCCTCCAACT
CAATCCGGAGGCAGTTATGGAGGTGGCGGCTACGGCCAAAACAATAACCGTGGTGGTCAAGACCCTCGTCAAGCCCGTCC
TCAAAAGCCAAAAGGTCTTTTAGAAGAGTTCGGCATCAATGTCACAGAAATTGCCCGCAAAGGGGATATTGACCCTGTCA
TTGGCCGTGATGAGGAGATTATCCGTGTCATCGAAATTCTCAACCGTCGAACCAAGAACAACCCGGTTCTGATTGGAGAA
CCTGGGGTCGGAAAAACTGCCGTTGTGGAAGGCCTGGCTCAAAAAATCGTCGATGGCGACGTTCCACATAAATTGCAAGG
AAAAGAAGTCATCCGCCTAGACGTCGTGAGCCTCGTTCAGGGCACAGGCATCCGTGGTCAATTCGAAGAACGCATGCAAA
AATTAATGGATGAAATTCGTCAACGCGAAGATGTTATTCTGTTCATCGACGAAATCCATGAAATTGTTGGCGCAGGATCA
GCCGGCGAAGGCAATATGGACGCTGGAAATATCCTCAAACCAGCCTTGGCGCGTGGAGAACTCCAATTAGTTGGGGCTAC
TACCCTCAATGAATACCGTATCATTGAAAAAGATGCGGCCTTGGAACGTCGGATGCAGCCCGTTAAGGTCGATGAACCAA
CGGTTGAAGAAACCATCACCATCCTCAAGGGCATCCAGAAAAAATACGAAGACTACCACCACGTCCACTATACAGACGGT
GCCATCGAAGCGGCAGCTATTCTTTCAAACCGTTACATCCAAGATCGCTTCCTGCCAGACAAGGCCATTGATCTGTTGGA
TGAAGCGGGATCTAAGATGAACCTGACCCTAAACTTTGTGGATCCAAAAGTGATCGATCAGCGCTTGATTGAAGCGGAAA
ACCTCAAAGCTCAAGCGACGCGCGAAGAAGACTTTGAAAAAGCAGCCTACTTCCGCGATCAAATCGCGAAATACAAGGAA
ATGCAAGGTCAACATGTCACTGATCAGGAGACCCCTGTCATCAGTGAAAAAACGATTGAACACATCGTTGAACAAAAGAC
CAATATTCCTGTTGGTGATTTGAAAGAAAAAGAACAGTCTCAATTGATCAATCTGGCTTCTGATTTGAAAGCTCATGTGA
TTGGTCAAGACGATGCAGTAGATAAAATCGCGAAAGCCATTCGACGCAATCGTGTCGGCTTAGGATCGCCTAACCGTCCA
ATCGGAAGCTTCCTCTTTGTCGGACCAACTGGTGTCGGAAAGACCGAACTGTCTAAACAATTAGCGATCGAGCTCTTTGG
CTCTGCAGACAATATGATCCGCTTTGACATGAGCGAATACATGGAAAAACATAGCGTAGCGAAACTAGTCGGAGCTCCTC
CGGGCTATGTTGGCTACGATGAAGCTGGACAACTAACGGAAAAGGTTCGTCGCAATCCTTACTCCCTCGTGTTGTTGGAT
GAAGTGGAAAAAGCCCATCCAGATGTCATGCACATGTTCTTGCAAGTTTTAGATGATGGCCGTTTGACAGATGGTCAAGG
CCGTACCGTCAGCTTTAAAGATACCATTATCATCATGACCTCTAATGCTGGAACCGGCAAGGCTGAGGCCAATGTTGGTT
TTGGAGCTGCTCGCGAAGGTCGAACCAACTCTGTACTTGGAGAACTCGGGAACTTCTTTAGCCCTGAATTCATGAACCGT
TTTGATGGCATCATTGAATTCCAACCTCTATCAAAAGAAAACCTTCTCCAAATCGTTACCCTCATGCTCGATGAAGTCAG
TCAACGTCTCGCACAAAATGAGATTCATCTGGATGTGACAGAGAAGGTCAAAGAAAAATTGGTCGATCTGGGATACGATC
CAAAAATGGGGGCCCGCCCACTCCGTCGTACCATCCAAGACCATATCGAAGATGCCATTACCGATTATTACCTGGAACAT
CCAAGTGAGAAACAACTCAAAGCCGTCATGACCAGCAATGGGAAAATCTCTATCAAGTCTGCTCACAAACCAGTTGAACA
GACTTCAGAATCATAA

Domains

Predicted by InterproScan.

• ATPase family associated with various cellular activities (AAA) (AAA) (156-269)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (650-725)

• AAA domain (Cdc48 subfamily) (AAA_2) (479-642)

• AAA lid domain (AAA_lid_9) (294-391)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus pneumoniae Rx1	86.968	100	0.871
clpE	Streptococcus pneumoniae D39	86.968	100	0.871
clpE	Streptococcus pneumoniae R6	86.968	100	0.871
clpE	Streptococcus pneumoniae TIGR4	86.968	100	0.871
clpE	Streptococcus mutans UA159	84.203	99.467	0.838
clpC	Lactococcus lactis subsp. cremoris KW2	75.529	100	0.76
clpC	Bacillus subtilis subsp. subtilis str. 168	50.426	93.742	0.473
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	47.328	87.217	0.413
clpC	Streptococcus pneumoniae Rx1	47.84	83.222	0.398
clpC	Streptococcus pneumoniae D39	47.84	83.222	0.398
clpC	Streptococcus pneumoniae TIGR4	47.68	83.222	0.397
clpC	Streptococcus mutans UA159	46.88	83.222	0.39
clpC	Streptococcus thermophilus LMD-9	47.03	82.956	0.39
clpC	Streptococcus thermophilus LMG 18311	46.785	82.823	0.387