Detailed information NTG0906452

Bioinformatically predicted

Overview

• Name: irvR
• Type: Regulator
• Locus tag: UXQ74_RS09965
• Genome accession: NZ_CP157771
• Coordinates: 2009715..2010428 (+)
• Length: 237 a.a.
• NCBI ID: WP_001031454.1
• Uniprot ID: A0A0H2XG68
• Organism: Staphylococcus aureus strain BSN117
• Function: regulate expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2004715..2015428

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
UXQ74_RS09915 (UXQ74_09915)	-	2005317..2007260 (-)	1944	WP_000700555.1	AAA family ATPase	-
UXQ74_RS09920 (UXQ74_09920)	-	2007269..2007532 (-)	264	WP_001205732.1	hypothetical protein	-
UXQ74_RS09925 (UXQ74_09925)	-	2007541..2007801 (-)	261	WP_000291510.1	DUF1108 family protein	-
UXQ74_RS09930 (UXQ74_09930)	-	2007806..2008108 (-)	303	WP_000165371.1	DUF2482 family protein	-
UXQ74_RS09935 (UXQ74_09935)	-	2008203..2008364 (-)	162	WP_000048132.1	DUF1270 family protein	-
UXQ74_RS09940 (UXQ74_09940)	-	2008361..2008684 (-)	324	WP_001120201.1	DUF771 domain-containing protein	-
UXQ74_RS09945 (UXQ74_09945)	-	2008739..2009119 (+)	381	WP_000762521.1	DUF2513 domain-containing protein	-
UXQ74_RS09950 (UXQ74_09950)	-	2009106..2009303 (-)	198	WP_001148862.1	hypothetical protein	-
UXQ74_RS09955 (UXQ74_09955)	-	2009319..2009582 (-)	264	WP_000854072.1	helix-turn-helix transcriptional regulator	-
UXQ74_RS09960 (UXQ74_09960)	-	2009579..2009752 (-)	174	WP_001801500.1	hypothetical protein	-
UXQ74_RS09965 (UXQ74_09965)	irvR	2009715..2010428 (+)	714	WP_001031454.1	XRE family transcriptional regulator	Regulator
UXQ74_RS09970 (UXQ74_09970)	-	2010444..2011376 (+)	933	WP_000759682.1	exonuclease domain-containing protein	-
UXQ74_RS09975 (UXQ74_09975)	-	2011382..2011723 (+)	342	WP_000591749.1	hypothetical protein	-
UXQ74_RS09980 (UXQ74_09980)	-	2011927..2012094 (+)	168	WP_031806878.1	hypothetical protein	-
UXQ74_RS09985 (UXQ74_09985)	-	2012234..2012773 (+)	540	WP_000391618.1	type II toxin-antitoxin system PemK/MazF family toxin	-
UXQ74_RS09990 (UXQ74_09990)	-	2012946..2013983 (+)	1038	WP_000857198.1	site-specific integrase	-
UXQ74_RS09995 (UXQ74_09995)	sph	2014034..2014864 (+)	831	Protein_1934	sphingomyelin phosphodiesterase	-

Sequence

Protein

• Length: 237 a.a.
• Molecular weight: 27017.58 Da
• Isoelectric Point: 5.0545

>NTDB_id=906452 UXQ74_RS09965 WP_001031454.1 2009715..2010428(+) (irvR) [Staphylococcus aureus strain BSN117]
MNKERNIIIAKNIRKFLNDSNMSQKKLAELINIKPSTLSDYLNLRSNPSHGVIQRIADVFEVGKSDIDTTYKDDNDITSI
YNKLTPPRQENVLNYANEQLEEQNSKGDNVVDINSYKQEKTPVNVNGCVSAGVGERLHDETLFTEMVKGPIPTHDLALKV
NGDSMEPMFKDGEIIFVEKTHNIKNGQIGIFIIEEEAYVKKVFVEDDRLTLVSLNKDYDDLHFYRNESVRLIGKVIL

Nucleotide

• Length: 714 bp

>NTDB_id=906452 UXQ74_RS09965 WP_001031454.1 2009715..2010428(+) (irvR) [Staphylococcus aureus strain BSN117]
ATGAACAAAGAAAGAAATATTATTATAGCCAAAAACATTAGAAAATTTCTCAACGATTCAAATATGTCTCAAAAGAAACT
TGCTGAACTCATTAACATAAAACCATCTACTTTAAGCGATTATTTAAATTTACGTTCCAACCCCTCTCACGGCGTTATAC
AAAGGATAGCTGATGTTTTCGAGGTTGGTAAAAGCGACATAGATACTACATACAAAGACGATAACGACATCACTTCCATA
TACAACAAACTCACACCTCCCCGCCAAGAAAACGTACTTAACTATGCAAATGAACAATTGGAAGAACAGAATTCTAAAGG
AGATAACGTTGTAGATATTAATTCATATAAACAGGAGAAAACTCCAGTTAACGTCAATGGTTGCGTCTCTGCTGGTGTAG
GAGAACGTTTACACGATGAAACGCTATTTACTGAAATGGTTAAAGGACCTATCCCCACACACGATTTAGCGTTAAAAGTA
AATGGTGATTCTATGGAACCTATGTTTAAAGATGGCGAAATCATATTTGTGGAGAAAACTCACAATATAAAGAATGGACA
AATTGGTATATTCATCATTGAAGAAGAAGCGTACGTTAAGAAAGTCTTTGTTGAAGATGATAGATTGACTCTAGTTTCAC
TAAATAAAGATTACGACGATCTACACTTTTATAGAAATGAAAGTGTGAGGTTAATTGGAAAAGTTATTTTATAA

Domains

Predicted by InterProScan.

• Peptidase S24-like (Peptidase_S24) (127-236)

• Helix-turn-helix (HTH_3) (13-63)

3D structure

• AlphaFold DB: A0A0H2XG68

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
irvR	Streptococcus mutans UA159	33.929	100	0.401