Detailed information NTG0905771

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: SGI39_RS09500
• Genome accession: NZ_CP138892
• Coordinates: 1937947..1938990 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain 1315
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1932947..1943990

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SGI39_RS09470 (SGI39_09470)	-	1933368..1934624 (-)	1257	WP_075583716.1	aminopeptidase	-
SGI39_RS09475 (SGI39_09475)	-	1934627..1934827 (-)	201	WP_000180460.1	DUF1128 family protein	-
SGI39_RS09480 (SGI39_09480)	-	1934974..1935438 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
SGI39_RS09485 (SGI39_09485)	-	1935445..1935720 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
SGI39_RS09490 (SGI39_09490)	-	1935998..1937215 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
SGI39_RS09495 (SGI39_09495)	vraR	1937328..1937957 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
SGI39_RS09500 (SGI39_09500)	vraS	1937947..1938990 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
SGI39_RS09505 (SGI39_09505)	liaF	1938987..1939688 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
SGI39_RS09510 (SGI39_09510)	-	1939703..1940089 (-)	387	WP_001110179.1	hypothetical protein	-
SGI39_RS09515 (SGI39_09515)	map	1940306..1941064 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
SGI39_RS09520 (SGI39_09520)	-	1941593..1942579 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
SGI39_RS09525 (SGI39_09525)	-	1943010..1943423 (-)	414	WP_001670387.1	hypothetical protein	-
SGI39_RS09530 (SGI39_09530)	-	1943452..1943562 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=905771 SGI39_RS09500 WP_001017131.1 1937947..1938990(-) (vraS) [Staphylococcus aureus strain 1315]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=905771 SGI39_RS09500 WP_001017131.1 1937947..1938990(-) (vraS) [Staphylococcus aureus strain 1315]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1