Detailed information NTG0905736

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: SGQ79_RS14020
• Genome accession: NZ_CP138889
• Coordinates: 2773739..2774626 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain 1221
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2768739..2779626

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SGQ79_RS13990 (SGQ79_13985)	-	2768757..2768845 (+)	89	Protein_2716	hypothetical protein	-
SGQ79_RS13995 (SGQ79_13990)	-	2768953..2769450 (-)	498	WP_001065267.1	glutathione peroxidase	-
SGQ79_RS14000 (SGQ79_13995)	-	2769460..2769720 (-)	261	WP_072434822.1	hypothetical protein	-
SGQ79_RS14005 (SGQ79_14000)	-	2770102..2770215 (-)	114	WP_217654589.1	hypothetical protein	-
SGQ79_RS14010 (SGQ79_14005)	-	2770879..2772879 (-)	2001	WP_000776746.1	ABC transporter permease	-
SGQ79_RS14015 (SGQ79_14010)	-	2772876..2773631 (-)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
SGQ79_RS14020 (SGQ79_14015)	braS	2773739..2774626 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
SGQ79_RS14025 (SGQ79_14020)	braR	2774637..2775302 (-)	666	WP_000697883.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
SGQ79_RS14030 (SGQ79_14025)	-	2775328..2775528 (-)	201	WP_000604723.1	hypothetical protein	-
SGQ79_RS14035 (SGQ79_14030)	-	2775726..2777150 (+)	1425	WP_000953731.1	alkaline phosphatase	-
SGQ79_RS14040	-	2777210..2777311 (-)	102	WP_000731972.1	SE2200 family small protein	-
SGQ79_RS14045 (SGQ79_14040)	-	2777433..2777888 (-)	456	WP_000106184.1	MarR family transcriptional regulator	-
SGQ79_RS14050 (SGQ79_14045)	-	2778134..2778895 (-)	762	WP_000323451.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=905736 SGQ79_RS14020 WP_000143420.1 2773739..2774626(-) (braS) [Staphylococcus aureus strain 1221]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=905736 SGQ79_RS14020 WP_000143420.1 2773739..2774626(-) (braS) [Staphylococcus aureus strain 1221]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATATGTAAAAGATAATGGTATCGGTATTAGTGAGGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993