Detailed information NTG0905689

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: SGQ77_RS09545
• Genome accession: NZ_CP138886
• Coordinates: 1946268..1947311 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain 1061
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1941268..1952311

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SGQ77_RS09515 (SGQ77_09515)	-	1941689..1942945 (-)	1257	WP_075583716.1	aminopeptidase	-
SGQ77_RS09520 (SGQ77_09520)	-	1942948..1943148 (-)	201	WP_000180460.1	DUF1128 family protein	-
SGQ77_RS09525 (SGQ77_09525)	-	1943295..1943759 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
SGQ77_RS09530 (SGQ77_09530)	-	1943766..1944041 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
SGQ77_RS09535 (SGQ77_09535)	-	1944319..1945536 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
SGQ77_RS09540 (SGQ77_09540)	vraR	1945649..1946278 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
SGQ77_RS09545 (SGQ77_09545)	vraS	1946268..1947311 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
SGQ77_RS09550 (SGQ77_09550)	liaF	1947308..1948009 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
SGQ77_RS09555 (SGQ77_09555)	-	1948024..1948410 (-)	387	WP_001110179.1	hypothetical protein	-
SGQ77_RS09560 (SGQ77_09560)	map	1948627..1949385 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
SGQ77_RS09565 (SGQ77_09565)	-	1949914..1950900 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
SGQ77_RS09570 (SGQ77_09570)	-	1951331..1951744 (-)	414	WP_001670387.1	hypothetical protein	-
SGQ77_RS09575 (SGQ77_09575)	-	1951773..1951883 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=905689 SGQ77_RS09545 WP_001017131.1 1946268..1947311(-) (vraS) [Staphylococcus aureus strain 1061]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=905689 SGQ77_RS09545 WP_001017131.1 1946268..1947311(-) (vraS) [Staphylococcus aureus strain 1061]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1