Detailed information NTG0905609

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: SGQ72_RS09455
• Genome accession: NZ_CP138881
• Coordinates: 1931243..1932286 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain 263
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1926243..1937286

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SGQ72_RS09425 (SGQ72_09420)	-	1926664..1927920 (-)	1257	WP_075583716.1	aminopeptidase	-
SGQ72_RS09430 (SGQ72_09425)	-	1927923..1928123 (-)	201	WP_000180460.1	DUF1128 family protein	-
SGQ72_RS09435 (SGQ72_09430)	-	1928270..1928734 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
SGQ72_RS09440 (SGQ72_09435)	-	1928741..1929016 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
SGQ72_RS09445 (SGQ72_09440)	-	1929294..1930511 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
SGQ72_RS09450 (SGQ72_09445)	vraR	1930624..1931253 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
SGQ72_RS09455 (SGQ72_09450)	vraS	1931243..1932286 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
SGQ72_RS09460 (SGQ72_09455)	liaF	1932283..1932984 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
SGQ72_RS09465 (SGQ72_09460)	-	1932999..1933385 (-)	387	WP_001110179.1	hypothetical protein	-
SGQ72_RS09470 (SGQ72_09465)	map	1933602..1934360 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
SGQ72_RS09475 (SGQ72_09470)	-	1934889..1935875 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
SGQ72_RS09480 (SGQ72_09475)	-	1936306..1936719 (-)	414	WP_001670387.1	hypothetical protein	-
SGQ72_RS09485 (SGQ72_09480)	-	1936748..1936858 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=905609 SGQ72_RS09455 WP_001017131.1 1931243..1932286(-) (vraS) [Staphylococcus aureus strain 263]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=905609 SGQ72_RS09455 WP_001017131.1 1931243..1932286(-) (vraS) [Staphylococcus aureus strain 263]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1