Detailed information NTG0905574

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: SGQ75_RS13500
• Genome accession: NZ_CP138880
• Coordinates: 2705568..2706455 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain 98
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2700568..2711455

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SGQ75_RS13470 (SGQ75_13470)	-	2700586..2700674 (+)	89	Protein_2611	hypothetical protein	-
SGQ75_RS13475 (SGQ75_13475)	-	2700782..2701279 (-)	498	WP_001065267.1	glutathione peroxidase	-
SGQ75_RS13480 (SGQ75_13480)	-	2701289..2701549 (-)	261	WP_072434822.1	hypothetical protein	-
SGQ75_RS13485 (SGQ75_13485)	-	2701931..2702044 (-)	114	WP_217654589.1	hypothetical protein	-
SGQ75_RS13490 (SGQ75_13490)	-	2702708..2704708 (-)	2001	WP_000776746.1	ABC transporter permease	-
SGQ75_RS13495 (SGQ75_13495)	-	2704705..2705460 (-)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
SGQ75_RS13500 (SGQ75_13500)	braS	2705568..2706455 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
SGQ75_RS13505 (SGQ75_13505)	braR	2706466..2707131 (-)	666	WP_000697883.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
SGQ75_RS13510 (SGQ75_13510)	-	2707157..2707357 (-)	201	WP_000604723.1	hypothetical protein	-
SGQ75_RS13515 (SGQ75_13515)	-	2707555..2708979 (+)	1425	WP_000953731.1	alkaline phosphatase	-
SGQ75_RS13520	-	2709039..2709140 (-)	102	WP_000731972.1	SE2200 family small protein	-
SGQ75_RS13525 (SGQ75_13525)	-	2709262..2709717 (-)	456	WP_000106184.1	MarR family transcriptional regulator	-
SGQ75_RS13530 (SGQ75_13530)	-	2709963..2710724 (-)	762	WP_000323451.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=905574 SGQ75_RS13500 WP_000143420.1 2705568..2706455(-) (braS) [Staphylococcus aureus strain 98]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=905574 SGQ75_RS13500 WP_000143420.1 2705568..2706455(-) (braS) [Staphylococcus aureus strain 98]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATATGTAAAAGATAATGGTATCGGTATTAGTGAGGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993