Detailed information NTG0905452

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: SGQ80_RS13470
• Genome accession: NZ_CP138873
• Coordinates: 2699767..2700654 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain 174
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2694767..2705654

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SGQ80_RS13440 (SGQ80_13435)	-	2694785..2694873 (+)	89	Protein_2605	hypothetical protein	-
SGQ80_RS13445 (SGQ80_13440)	-	2694981..2695478 (-)	498	WP_001065267.1	glutathione peroxidase	-
SGQ80_RS13450 (SGQ80_13445)	-	2695488..2695748 (-)	261	WP_072434822.1	hypothetical protein	-
SGQ80_RS13455 (SGQ80_13450)	-	2696130..2696243 (-)	114	WP_217654589.1	hypothetical protein	-
SGQ80_RS13460 (SGQ80_13455)	-	2696907..2698907 (-)	2001	WP_000776746.1	ABC transporter permease	-
SGQ80_RS13465 (SGQ80_13460)	-	2698904..2699659 (-)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
SGQ80_RS13470 (SGQ80_13465)	braS	2699767..2700654 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
SGQ80_RS13475 (SGQ80_13470)	braR	2700665..2701330 (-)	666	WP_000697883.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
SGQ80_RS13480 (SGQ80_13475)	-	2701356..2701556 (-)	201	WP_000604723.1	hypothetical protein	-
SGQ80_RS13485 (SGQ80_13480)	-	2701754..2703178 (+)	1425	WP_000953731.1	alkaline phosphatase	-
SGQ80_RS13490	-	2703238..2703339 (-)	102	WP_000731972.1	SE2200 family small protein	-
SGQ80_RS13495 (SGQ80_13490)	-	2703461..2703916 (-)	456	WP_000106184.1	MarR family transcriptional regulator	-
SGQ80_RS13500 (SGQ80_13495)	-	2704162..2704923 (-)	762	WP_000323451.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=905452 SGQ80_RS13470 WP_000143420.1 2699767..2700654(-) (braS) [Staphylococcus aureus strain 174]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=905452 SGQ80_RS13470 WP_000143420.1 2699767..2700654(-) (braS) [Staphylococcus aureus strain 174]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATATGTAAAAGATAATGGTATCGGTATTAGTGAGGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993