Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   SGQ80_RS10280 Genome accession   NZ_CP138873
Coordinates   2073335..2074051 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain 174     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2068335..2079051
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SGQ80_RS10250 (SGQ80_10245) - 2068643..2069269 (+) 627 WP_000522384.1 nitroreductase family protein -
  SGQ80_RS10255 (SGQ80_10250) - 2069539..2070324 (+) 786 WP_000867943.1 carbon-nitrogen family hydrolase -
  SGQ80_RS10260 (SGQ80_10255) - 2070923..2071057 (-) 135 WP_001549197.1 delta-lysin family phenol-soluble modulin -
  SGQ80_RS10265 (SGQ80_10260) agrB 2071293..2071862 (+) 570 WP_001105713.1 accessory gene regulator AgrB -
  SGQ80_RS10270 (SGQ80_10265) agrD 2071859..2071999 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  SGQ80_RS10275 (SGQ80_10270) agrC 2072024..2073316 (+) 1293 WP_001670396.1 quorum-sensing sensor histidine kinase AgrC -
  SGQ80_RS10280 (SGQ80_10275) agrA 2073335..2074051 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  SGQ80_RS10285 (SGQ80_10280) - 2074123..2074230 (+) 108 WP_031789494.1 hypothetical protein -
  SGQ80_RS10290 (SGQ80_10285) - 2074419..2075378 (-) 960 WP_001253301.1 carbohydrate kinase -
  SGQ80_RS10295 (SGQ80_10290) - 2075375..2076859 (-) 1485 WP_000141410.1 glycoside hydrolase family 32 protein -
  SGQ80_RS10300 (SGQ80_10295) - 2077008..2077958 (-) 951 WP_000790322.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=905448 SGQ80_RS10280 WP_000688492.1 2073335..2074051(+) (agrA) [Staphylococcus aureus strain 174]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=905448 SGQ80_RS10280 WP_000688492.1 2073335..2074051(+) (agrA) [Staphylococcus aureus strain 174]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATCCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCATAGTGAACTTACGTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACACGTATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATCGAATCTATAG
ATTCGAAAGAGCGCATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1