Detailed information NTG0905405

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: SGQ76_RS09510
• Genome accession: NZ_CP138869
• Coordinates: 1942265..1943308 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain 171
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1937265..1948308

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SGQ76_RS09480 (SGQ76_09480)	-	1937686..1938942 (-)	1257	WP_075583716.1	aminopeptidase	-
SGQ76_RS09485 (SGQ76_09485)	-	1938945..1939145 (-)	201	WP_000180460.1	DUF1128 family protein	-
SGQ76_RS09490 (SGQ76_09490)	-	1939292..1939756 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
SGQ76_RS09495 (SGQ76_09495)	-	1939763..1940038 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
SGQ76_RS09500 (SGQ76_09500)	-	1940316..1941533 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
SGQ76_RS09505 (SGQ76_09505)	vraR	1941646..1942275 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
SGQ76_RS09510 (SGQ76_09510)	vraS	1942265..1943308 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
SGQ76_RS09515 (SGQ76_09515)	liaF	1943305..1944006 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
SGQ76_RS09520 (SGQ76_09520)	-	1944021..1944407 (-)	387	WP_001110179.1	hypothetical protein	-
SGQ76_RS09525 (SGQ76_09525)	map	1944624..1945382 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
SGQ76_RS09530 (SGQ76_09530)	-	1945853..1946839 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
SGQ76_RS09535 (SGQ76_09535)	-	1947270..1947683 (-)	414	WP_001670387.1	hypothetical protein	-
SGQ76_RS09540 (SGQ76_09540)	-	1947712..1947822 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=905405 SGQ76_RS09510 WP_001017131.1 1942265..1943308(-) (vraS) [Staphylococcus aureus strain 171]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=905405 SGQ76_RS09510 WP_001017131.1 1942265..1943308(-) (vraS) [Staphylococcus aureus strain 171]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1