Detailed information NTG0905370

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: SGQ81_RS13575
• Genome accession: NZ_CP138866
• Coordinates: 2718764..2719651 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain 160
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2713764..2724651

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SGQ81_RS13545 (SGQ81_13545)	-	2713782..2713870 (+)	89	Protein_2626	hypothetical protein	-
SGQ81_RS13550 (SGQ81_13550)	-	2713978..2714475 (-)	498	WP_001065267.1	glutathione peroxidase	-
SGQ81_RS13555 (SGQ81_13555)	-	2714485..2714745 (-)	261	WP_072434822.1	hypothetical protein	-
SGQ81_RS13560 (SGQ81_13560)	-	2715127..2715240 (-)	114	WP_217654589.1	hypothetical protein	-
SGQ81_RS13565 (SGQ81_13565)	-	2715904..2717904 (-)	2001	WP_000776746.1	ABC transporter permease	-
SGQ81_RS13570 (SGQ81_13570)	-	2717901..2718656 (-)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
SGQ81_RS13575 (SGQ81_13575)	braS	2718764..2719651 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
SGQ81_RS13580 (SGQ81_13580)	braR	2719662..2720327 (-)	666	WP_000697883.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
SGQ81_RS13585 (SGQ81_13585)	-	2720353..2720553 (-)	201	WP_000604723.1	hypothetical protein	-
SGQ81_RS13590 (SGQ81_13590)	-	2720751..2722175 (+)	1425	WP_000953731.1	alkaline phosphatase	-
SGQ81_RS13595	-	2722235..2722336 (-)	102	WP_000731972.1	SE2200 family small protein	-
SGQ81_RS13600 (SGQ81_13600)	-	2722458..2722913 (-)	456	WP_000106184.1	MarR family transcriptional regulator	-
SGQ81_RS13605 (SGQ81_13605)	-	2723159..2723920 (-)	762	WP_000323451.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=905370 SGQ81_RS13575 WP_000143420.1 2718764..2719651(-) (braS) [Staphylococcus aureus strain 160]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=905370 SGQ81_RS13575 WP_000143420.1 2718764..2719651(-) (braS) [Staphylococcus aureus strain 160]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATATGTAAAAGATAATGGTATCGGTATTAGTGAGGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993