Detailed information NTG0905327

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: SGQ70_RS13680
• Genome accession: NZ_CP138864
• Coordinates: 2736741..2737628 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain 136
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2731741..2742628

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SGQ70_RS13650 (SGQ70_13645)	-	2731759..2731847 (+)	89	Protein_2647	hypothetical protein	-
SGQ70_RS13655 (SGQ70_13650)	-	2731955..2732452 (-)	498	WP_001065267.1	glutathione peroxidase	-
SGQ70_RS13660 (SGQ70_13655)	-	2732462..2732722 (-)	261	WP_072434822.1	hypothetical protein	-
SGQ70_RS13665 (SGQ70_13660)	-	2733104..2733217 (-)	114	WP_217654589.1	hypothetical protein	-
SGQ70_RS13670 (SGQ70_13665)	-	2733881..2735881 (-)	2001	WP_000776746.1	ABC transporter permease	-
SGQ70_RS13675 (SGQ70_13670)	-	2735878..2736633 (-)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
SGQ70_RS13680 (SGQ70_13675)	braS	2736741..2737628 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
SGQ70_RS13685 (SGQ70_13680)	braR	2737639..2738304 (-)	666	WP_000697883.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
SGQ70_RS13690 (SGQ70_13685)	-	2738330..2738530 (-)	201	WP_000604723.1	hypothetical protein	-
SGQ70_RS13695 (SGQ70_13690)	-	2738728..2740152 (+)	1425	WP_000953731.1	alkaline phosphatase	-
SGQ70_RS13700	-	2740212..2740313 (-)	102	WP_000731972.1	SE2200 family small protein	-
SGQ70_RS13705 (SGQ70_13700)	-	2740435..2740890 (-)	456	WP_000106184.1	MarR family transcriptional regulator	-
SGQ70_RS13710 (SGQ70_13705)	-	2741136..2741897 (-)	762	WP_000323451.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=905327 SGQ70_RS13680 WP_000143420.1 2736741..2737628(-) (braS) [Staphylococcus aureus strain 136]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=905327 SGQ70_RS13680 WP_000143420.1 2736741..2737628(-) (braS) [Staphylococcus aureus strain 136]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATATGTAAAAGATAATGGTATCGGTATTAGTGAGGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993