Detailed information NTG0905286

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: SGQ74_RS13660
• Genome accession: NZ_CP138862
• Coordinates: 2735599..2736486 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain 102
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2730599..2741486

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SGQ74_RS13630 (SGQ74_13620)	-	2730617..2730705 (+)	89	Protein_2643	hypothetical protein	-
SGQ74_RS13635 (SGQ74_13625)	-	2730813..2731310 (-)	498	WP_001065267.1	glutathione peroxidase	-
SGQ74_RS13640 (SGQ74_13630)	-	2731320..2731580 (-)	261	WP_072434822.1	hypothetical protein	-
SGQ74_RS13645 (SGQ74_13635)	-	2731962..2732075 (-)	114	WP_217654589.1	hypothetical protein	-
SGQ74_RS13650 (SGQ74_13640)	-	2732739..2734739 (-)	2001	WP_000776746.1	ABC transporter permease	-
SGQ74_RS13655 (SGQ74_13645)	-	2734736..2735491 (-)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
SGQ74_RS13660 (SGQ74_13650)	braS	2735599..2736486 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
SGQ74_RS13665 (SGQ74_13655)	braR	2736497..2737162 (-)	666	WP_000697883.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
SGQ74_RS13670 (SGQ74_13660)	-	2737188..2737388 (-)	201	WP_000604723.1	hypothetical protein	-
SGQ74_RS13675 (SGQ74_13665)	-	2737586..2739010 (+)	1425	WP_000953731.1	alkaline phosphatase	-
SGQ74_RS13680	-	2739070..2739171 (-)	102	WP_000731972.1	SE2200 family small protein	-
SGQ74_RS13685 (SGQ74_13675)	-	2739293..2739748 (-)	456	WP_000106184.1	MarR family transcriptional regulator	-
SGQ74_RS13690 (SGQ74_13680)	-	2739994..2740755 (-)	762	WP_000323451.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=905286 SGQ74_RS13660 WP_000143420.1 2735599..2736486(-) (braS) [Staphylococcus aureus strain 102]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=905286 SGQ74_RS13660 WP_000143420.1 2735599..2736486(-) (braS) [Staphylococcus aureus strain 102]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATATGTAAAAGATAATGGTATCGGTATTAGTGAGGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993