Detailed information NTG0905245

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: SGQ78_RS13480
• Genome accession: NZ_CP138859
• Coordinates: 2699231..2700118 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain 15
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2694231..2705118

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SGQ78_RS13450 (SGQ78_13450)	-	2694249..2694337 (+)	89	Protein_2607	hypothetical protein	-
SGQ78_RS13455 (SGQ78_13455)	-	2694445..2694942 (-)	498	WP_001065267.1	glutathione peroxidase	-
SGQ78_RS13460 (SGQ78_13460)	-	2694952..2695212 (-)	261	WP_072434822.1	hypothetical protein	-
SGQ78_RS13465 (SGQ78_13465)	-	2695594..2695707 (-)	114	WP_217654589.1	hypothetical protein	-
SGQ78_RS13470 (SGQ78_13470)	-	2696371..2698371 (-)	2001	WP_000776746.1	ABC transporter permease	-
SGQ78_RS13475 (SGQ78_13475)	-	2698368..2699123 (-)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
SGQ78_RS13480 (SGQ78_13480)	braS	2699231..2700118 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
SGQ78_RS13485 (SGQ78_13485)	braR	2700129..2700794 (-)	666	WP_000697883.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
SGQ78_RS13490 (SGQ78_13490)	-	2700820..2701020 (-)	201	WP_000604723.1	hypothetical protein	-
SGQ78_RS13495 (SGQ78_13495)	-	2701218..2702642 (+)	1425	WP_000953731.1	alkaline phosphatase	-
SGQ78_RS13500	-	2702702..2702803 (-)	102	WP_000731972.1	SE2200 family small protein	-
SGQ78_RS13505 (SGQ78_13505)	-	2702925..2703380 (-)	456	WP_000106184.1	MarR family transcriptional regulator	-
SGQ78_RS13510 (SGQ78_13510)	-	2703626..2704387 (-)	762	WP_000323451.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=905245 SGQ78_RS13480 WP_000143420.1 2699231..2700118(-) (braS) [Staphylococcus aureus strain 15]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=905245 SGQ78_RS13480 WP_000143420.1 2699231..2700118(-) (braS) [Staphylococcus aureus strain 15]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATATGTAAAAGATAATGGTATCGGTATTAGTGAGGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993